Efficacy and Safety of Plecanatide in Children 6 to < 18 Years of Age With Irritable Bowel Syndrome With Constipation (IBS-C)
Condition:   Irritable Bowel Syndrome With Constipation Interventions:   Drug: Plecanatide;   Drug: Matching placebo Sponsor:   Synergy Pharmaceuticals Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 24, 2018 Category: Research Source Type: clinical trials

Efficacy and indication optimization of Chinese medicine ( Tiao-Chang Ke-Min granules) for diarrhea-predominant irritable bowel syndrome: study protocol for a randomized controlled trial
DiscussionThis trial may provide high-quality evidence on the efficacy and safety of TCKM granules for IBS and a more accurate indication. Importantly, this trial will provide a new research method for improving the therapeutic effects of CM for clinicians and researchers. To address IBS relapse assessment, a series of special definitions of relapse incidents has been made for this trial.Trial registrationChinese Clinical Trial Registry, ID:ChiCTR-IOR-17010600. Registered on 9 February 2017. (Source: Trials)
Source: Trials - July 11, 2018 Category: Research Source Type: clinical trials

A Trial of Linaclotide 290 μg in Patients With Irritable Bowel Syndrome With Constipation
Condition:   Irritable Bowel Syndrome Characterized by Constipation Interventions:   Drug: Linaclotide;   Drug: Placebo Sponsors:   Ironwood Pharmaceuticals, Inc.;   Allergan Sales, LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 29, 2018 Category: Research Source Type: clinical trials

A Trial of Linaclotide 290 μg in Patients With Irritable Bowel Syndrome With Constipation
Condition:   Irritable Bowel Syndrome Characterized by Constipation Interventions:   Drug: Linaclotide;   Drug: Placebo Sponsors:   Ironwood Pharmaceuticals, Inc.;   Allergan Sales, LLC Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 29, 2018 Category: Research Source Type: clinical trials

A Trial of Linaclotide 290 μg in Patients With Irritable Bowel Syndrome With Constipation
Condition:   Irritable Bowel Syndrome Characterized by Constipation Interventions:   Drug: Linaclotide;   Drug: Placebo Sponsors:   Ironwood Pharmaceuticals, Inc.;   Allergan Sales, LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 29, 2018 Category: Research Source Type: clinical trials

Changes in Microbiota and Metabolomic Profile Between Rifaximin Responders and Non-responders In Diarrhoea-Predominant Irritable Bowel Syndrome
Condition:   Irritable Bowel Syndrome With Diarrhea Intervention:   Drug: Rifaximin Oral Tablet Sponsors:   National University Hospital, Singapore;   National University, Singapore Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 15, 2018 Category: Research Source Type: clinical trials

TReatment of Irritable Bowel Syndrome With Diarrhoea Using Titrated ONdansetron Trial
Condition:   IBS - Irritable Bowel Syndrome Intervention:   Drug: Ondansetron Sponsors:   University of Leeds;   Barnsley Hospital NHS Foundation Trust;   Barts & The London NHS Trust;   County Durham and Darlington NHS Foundation Trust;   Flinders University;   The Leeds Teaching Hospitals NHS Trust;   London North West Healthcare NHS Trust;   Lothian Health Board;   Queen Mary Univ...
Source: ClinicalTrials.gov - June 13, 2018 Category: Research Source Type: clinical trials