Randomised, double-blind, placebo controlled multi-centre study to assess the efficacy, tolerability and safety of Enterosgel ® in the treatment of irritable bowel syndrome with diarrhoea (IBS-D) in adults
DiscussionThis is the first large scale randomised controlled trial investigating Enterosgel ® in IBS-D. A study design with blinded phase followed by an open-label phase was chosen to encourage participation and study completion. Demonstrating that Enterosgel® is effective and safe in IBS-D could encourage adoption by patients and healthcare professionals and foster future clinical trial s assessing its use in related conditions.Trial registrationISRCTN17149988. Prospectively registered on 14 November 2017. (Source: Trials)
Source: Trials - January 29, 2020 Category: Research Source Type: clinical trials

Ethosuximide and Pentoxifylline in the Treatment of Abdominal Pain Related to Irritable Bowel Syndrome
Condition:   IBS - Irritable Bowel Syndrome Interventions:   Drug: pentoxyifylline;   Drug: Mebeverine;   Drug: ethosuximide Sponsor:   Tanta University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 3, 2020 Category: Research Source Type: clinical trials

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in IBS
Conditions:   Irritable Bowel;   Irritable Bowel Syndrome;   Irritable Bowel Syndrome With Diarrhea;   Irritable Bowel Syndrome Mixed;   Irritable Bowel Syndrome With Constipation;   Irritable Bowel Syndrome Without Diarrhea;   Irritable Bowel Syndrome Aggravated;   Irritable Bowel Syndrome Characterized by Constipation;   Irritable Bowel Syndrome Characterised by Alternating Bowel Habit Intervention:   Other: No intervention Sponsor:   ProgenaBiome Not ye...
Source: ClinicalTrials.gov - January 2, 2020 Category: Research Source Type: clinical trials

Effectiveness of Probiotics Stabilized With Cryoprotection Technology in Patients With Irritable Bowel Syndrome
Condition:   Irritable Bowel Syndrome Intervention:   Dietary Supplement: Probiotic Sponsors:   Children's Memorial Health Institute, Poland;   Medical University of Lublin Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 20, 2019 Category: Research Source Type: clinical trials

Frequency of Sleep Abnormalities in Patients With Irritable Bowel Syndrome and Effect of Pharmacological Intervention
Condition:   Irritable Bowel Syndrome Interventions:   Drug: Melatonin and standard therapy for IBS;   Other: Standard medical therapy and placebo Sponsor:   Sanjay Gandhi Postgraduate Institute of Medical Sciences Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 10, 2019 Category: Research Source Type: clinical trials