Repetitive Sulfur Dioxide Exposure in Mice Models Post-Deployment Respiratory Syndrome
Am J Physiol Lung Cell Mol Physiol. 2024 Feb 27. doi: 10.1152/ajplung.00239.2023. Online ahead of print.ABSTRACTSoldiers deployed to Iraq and Afghanistan have a higher prevalence of respiratory symptoms than non-deployed military personnel and some have been shown to have a constellation of findings on lung biopsy termed post-deployment respiratory syndrome (PDRS). Since many of the subjects in this cohort reported exposure to sulfur dioxide (SO2), we developed a model of repetitive exposure to SO2 in mice that phenocopies many aspects of PDRS, including adaptive immune activation, airway wall remodeling, and pulmonary vas...
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - February 27, 2024 Category: Cytology Authors: Sergey S Gutor Rodrigo I Salinas David S Nichols Julia M R Bazzano Wei Han Jason J Gokey Georgii Vasiukov James D West Dawn C Newcomb Anna E Dikalova Bradley W Richmond Sergey I Dikalov Timothy S Blackwell Vasiliy V Polosukhin Source Type: research
Repetitive Sulfur Dioxide Exposure in Mice Models Post-Deployment Respiratory Syndrome
Am J Physiol Lung Cell Mol Physiol. 2024 Feb 27. doi: 10.1152/ajplung.00239.2023. Online ahead of print.ABSTRACTSoldiers deployed to Iraq and Afghanistan have a higher prevalence of respiratory symptoms than non-deployed military personnel and some have been shown to have a constellation of findings on lung biopsy termed post-deployment respiratory syndrome (PDRS). Since many of the subjects in this cohort reported exposure to sulfur dioxide (SO2), we developed a model of repetitive exposure to SO2 in mice that phenocopies many aspects of PDRS, including adaptive immune activation, airway wall remodeling, and pulmonary vas...
Source: Am J Physiol Lung Ce... - February 27, 2024 Category: Respiratory Medicine Authors: Sergey S Gutor Rodrigo I Salinas David S Nichols Julia M R Bazzano Wei Han Jason J Gokey Georgii Vasiukov James D West Dawn C Newcomb Anna E Dikalova Bradley W Richmond Sergey I Dikalov Timothy S Blackwell Vasiliy V Polosukhin Source Type: research
Repetitive Sulfur Dioxide Exposure in Mice Models Post-Deployment Respiratory Syndrome
Am J Physiol Lung Cell Mol Physiol. 2024 Feb 27. doi: 10.1152/ajplung.00239.2023. Online ahead of print.ABSTRACTSoldiers deployed to Iraq and Afghanistan have a higher prevalence of respiratory symptoms than non-deployed military personnel and some have been shown to have a constellation of findings on lung biopsy termed post-deployment respiratory syndrome (PDRS). Since many of the subjects in this cohort reported exposure to sulfur dioxide (SO2), we developed a model of repetitive exposure to SO2 in mice that phenocopies many aspects of PDRS, including adaptive immune activation, airway wall remodeling, and pulmonary vas...
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - February 27, 2024 Category: Cytology Authors: Sergey S Gutor Rodrigo I Salinas David S Nichols Julia M R Bazzano Wei Han Jason J Gokey Georgii Vasiukov James D West Dawn C Newcomb Anna E Dikalova Bradley W Richmond Sergey I Dikalov Timothy S Blackwell Vasiliy V Polosukhin Source Type: research
Repetitive Sulfur Dioxide Exposure in Mice Models Post-Deployment Respiratory Syndrome
Am J Physiol Lung Cell Mol Physiol. 2024 Feb 27. doi: 10.1152/ajplung.00239.2023. Online ahead of print.ABSTRACTSoldiers deployed to Iraq and Afghanistan have a higher prevalence of respiratory symptoms than non-deployed military personnel and some have been shown to have a constellation of findings on lung biopsy termed post-deployment respiratory syndrome (PDRS). Since many of the subjects in this cohort reported exposure to sulfur dioxide (SO2), we developed a model of repetitive exposure to SO2 in mice that phenocopies many aspects of PDRS, including adaptive immune activation, airway wall remodeling, and pulmonary vas...
Source: Am J Physiol Lung Ce... - February 27, 2024 Category: Respiratory Medicine Authors: Sergey S Gutor Rodrigo I Salinas David S Nichols Julia M R Bazzano Wei Han Jason J Gokey Georgii Vasiukov James D West Dawn C Newcomb Anna E Dikalova Bradley W Richmond Sergey I Dikalov Timothy S Blackwell Vasiliy V Polosukhin Source Type: research
Repetitive Sulfur Dioxide Exposure in Mice Models Post-Deployment Respiratory Syndrome
Am J Physiol Lung Cell Mol Physiol. 2024 Feb 27. doi: 10.1152/ajplung.00239.2023. Online ahead of print.ABSTRACTSoldiers deployed to Iraq and Afghanistan have a higher prevalence of respiratory symptoms than non-deployed military personnel and some have been shown to have a constellation of findings on lung biopsy termed post-deployment respiratory syndrome (PDRS). Since many of the subjects in this cohort reported exposure to sulfur dioxide (SO2), we developed a model of repetitive exposure to SO2 in mice that phenocopies many aspects of PDRS, including adaptive immune activation, airway wall remodeling, and pulmonary vas...
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - February 27, 2024 Category: Cytology Authors: Sergey S Gutor Rodrigo I Salinas David S Nichols Julia M R Bazzano Wei Han Jason J Gokey Georgii Vasiukov James D West Dawn C Newcomb Anna E Dikalova Bradley W Richmond Sergey I Dikalov Timothy S Blackwell Vasiliy V Polosukhin Source Type: research
Repetitive Sulfur Dioxide Exposure in Mice Models Post-Deployment Respiratory Syndrome
Am J Physiol Lung Cell Mol Physiol. 2024 Feb 27. doi: 10.1152/ajplung.00239.2023. Online ahead of print.ABSTRACTSoldiers deployed to Iraq and Afghanistan have a higher prevalence of respiratory symptoms than non-deployed military personnel and some have been shown to have a constellation of findings on lung biopsy termed post-deployment respiratory syndrome (PDRS). Since many of the subjects in this cohort reported exposure to sulfur dioxide (SO2), we developed a model of repetitive exposure to SO2 in mice that phenocopies many aspects of PDRS, including adaptive immune activation, airway wall remodeling, and pulmonary vas...
Source: Am J Physiol Lung Ce... - February 27, 2024 Category: Respiratory Medicine Authors: Sergey S Gutor Rodrigo I Salinas David S Nichols Julia M R Bazzano Wei Han Jason J Gokey Georgii Vasiukov James D West Dawn C Newcomb Anna E Dikalova Bradley W Richmond Sergey I Dikalov Timothy S Blackwell Vasiliy V Polosukhin Source Type: research
Repetitive Sulfur Dioxide Exposure in Mice Models Post-Deployment Respiratory Syndrome
Am J Physiol Lung Cell Mol Physiol. 2024 Feb 27. doi: 10.1152/ajplung.00239.2023. Online ahead of print.ABSTRACTSoldiers deployed to Iraq and Afghanistan have a higher prevalence of respiratory symptoms than non-deployed military personnel and some have been shown to have a constellation of findings on lung biopsy termed post-deployment respiratory syndrome (PDRS). Since many of the subjects in this cohort reported exposure to sulfur dioxide (SO2), we developed a model of repetitive exposure to SO2 in mice that phenocopies many aspects of PDRS, including adaptive immune activation, airway wall remodeling, and pulmonary vas...
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - February 27, 2024 Category: Cytology Authors: Sergey S Gutor Rodrigo I Salinas David S Nichols Julia M R Bazzano Wei Han Jason J Gokey Georgii Vasiukov James D West Dawn C Newcomb Anna E Dikalova Bradley W Richmond Sergey I Dikalov Timothy S Blackwell Vasiliy V Polosukhin Source Type: research
Repetitive Sulfur Dioxide Exposure in Mice Models Post-Deployment Respiratory Syndrome
Am J Physiol Lung Cell Mol Physiol. 2024 Feb 27. doi: 10.1152/ajplung.00239.2023. Online ahead of print.ABSTRACTSoldiers deployed to Iraq and Afghanistan have a higher prevalence of respiratory symptoms than non-deployed military personnel and some have been shown to have a constellation of findings on lung biopsy termed post-deployment respiratory syndrome (PDRS). Since many of the subjects in this cohort reported exposure to sulfur dioxide (SO2), we developed a model of repetitive exposure to SO2 in mice that phenocopies many aspects of PDRS, including adaptive immune activation, airway wall remodeling, and pulmonary vas...
Source: Am J Physiol Lung Ce... - February 27, 2024 Category: Respiratory Medicine Authors: Sergey S Gutor Rodrigo I Salinas David S Nichols Julia M R Bazzano Wei Han Jason J Gokey Georgii Vasiukov James D West Dawn C Newcomb Anna E Dikalova Bradley W Richmond Sergey I Dikalov Timothy S Blackwell Vasiliy V Polosukhin Source Type: research
Repetitive Sulfur Dioxide Exposure in Mice Models Post-Deployment Respiratory Syndrome
Am J Physiol Lung Cell Mol Physiol. 2024 Feb 27. doi: 10.1152/ajplung.00239.2023. Online ahead of print.ABSTRACTSoldiers deployed to Iraq and Afghanistan have a higher prevalence of respiratory symptoms than non-deployed military personnel and some have been shown to have a constellation of findings on lung biopsy termed post-deployment respiratory syndrome (PDRS). Since many of the subjects in this cohort reported exposure to sulfur dioxide (SO2), we developed a model of repetitive exposure to SO2 in mice that phenocopies many aspects of PDRS, including adaptive immune activation, airway wall remodeling, and pulmonary vas...
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - February 27, 2024 Category: Cytology Authors: Sergey S Gutor Rodrigo I Salinas David S Nichols Julia M R Bazzano Wei Han Jason J Gokey Georgii Vasiukov James D West Dawn C Newcomb Anna E Dikalova Bradley W Richmond Sergey I Dikalov Timothy S Blackwell Vasiliy V Polosukhin Source Type: research
The violent death toll from the Iraq War: 2003 –2023
by Michael Spagat
From the beginning of the Iraq war, in March of 2003, to the present day, controversy has swirled around the death toll of the war. This paper narrows down the range of uncertainty for the numbers and trends in violent deaths in the war. I assemble and appraise all primary sources that cover the p eriod from March of 2003 onwards—six sample surveys plus a casualty recording project (Iraq Body Count [IBC]). Data permitting, I present cumulative monthly figures with, for the surveys, 95% bootstrapped uncertainty intervals. The analysis uncovers a core of high-quality mainstream sources that a re highly c...
Source: PLoS One - February 27, 2024 Category: Biomedical Science Authors: Michael Spagat Source Type: research
Effects of combined metformin and cabergoline versus metformin alone on ovarian and hormonal activities in Iraqi patients with PCOS and hyperprolactinemia: a randomized clinical trial
J Med Life. 2023 Nov;16(11):1615-1621. doi: 10.25122/jml-2023-0317.ABSTRACTPolycystic ovary syndrome (PCOS) is one of the most prevalent metabolic diseases during female reproductive life, often associated with insulin resistance and hyperprolactinemia. The efficacy of metformin and cabergoline for managing PCOS remains debated in the literature. This three-arm interventional study in Iraq assessed the effects of these drugs on body mass index (BMI), hormonal balance, and uterine artery blood flow in 75 women with PCOS and hyperprolactinemia. Participants were randomized into three groups: metformin (500 mg twice daily), c...
Source: Journal of Medicine and Life - February 26, 2024 Category: General Medicine Authors: Inas Naser Hamad Sinaa Abdul Amir Kadhim Hayder Adnan Fawzi Shoroq Mohammed Al-Temimi Bassim Mohammad Asma Swadi Source Type: research
Association between < em > CNR1 < /em > gene polymorphisms and susceptibility to diabetic nephropathy in Iraqi patients with T2DM
J Med Life. 2023 Nov;16(11):1663-1669. doi: 10.25122/jml-2023-0181.ABSTRACTIn individuals with type 2 diabetes mellitus (T2DM), the cannabinoid receptor 1 (CNR1) gene polymorphism has been linked to diabetic nephropathy (DN). Different renal disorders, including DN, have been found to alter cannabinoid (CB) receptor expression and activation. This cross-sectional study aimed to investigate the relationship between CNR1 rs1776966256 and rs1243008337 genetic variants and the risk of developing DN in Iraqi patients with T2DM. The study included 100 patients with T2DM, divided into two groups: 50 with DN and 50 without DN. Gen...
Source: Journal of Medicine and Life - February 26, 2024 Category: General Medicine Authors: Raghda Hisham Aljorani Eman Saadi Saleh Khalaf Gata Al Mohammadawi Source Type: research
Epidemiological profile of hemophilia A in Karbala-Iraq
In this study, one-third of patients' presentations started in the first year of life. The most common type was severe hemophilia A (factor VIII activity < 1%). Consequently, more than half of the patients were treated with factor VIII concentrate. Four patients had hepatitis C, while HIV was confirmed in one patient. The epidemiological or clinical parameters of hemophilia A patients in Karbala seem similar to those in other cities in Iraq. By considering this preliminary data, further comprehensive studies for patients with hemophilia and associated complications in other provinces or cities in Iraq are highly suggest...
Source: Journal of Medicine and Life - February 26, 2024 Category: General Medicine Authors: Inas Muayad Mohammed Ali Ashwaq Ali Hussein Israa Mustafa Salih Al-Musawi Sabeeha Sahib Hadi Hillawi Naus Salih Kadhim Abdulkareem Alaiwi Jasim Source Type: research
Effects of combined metformin and cabergoline versus metformin alone on ovarian and hormonal activities in Iraqi patients with PCOS and hyperprolactinemia: a randomized clinical trial
J Med Life. 2023 Nov;16(11):1615-1621. doi: 10.25122/jml-2023-0317.ABSTRACTPolycystic ovary syndrome (PCOS) is one of the most prevalent metabolic diseases during female reproductive life, often associated with insulin resistance and hyperprolactinemia. The efficacy of metformin and cabergoline for managing PCOS remains debated in the literature. This three-arm interventional study in Iraq assessed the effects of these drugs on body mass index (BMI), hormonal balance, and uterine artery blood flow in 75 women with PCOS and hyperprolactinemia. Participants were randomized into three groups: metformin (500 mg twice daily), c...
Source: Journal of Medicine and Life - February 26, 2024 Category: General Medicine Authors: Inas Naser Hamad Sinaa Abdul Amir Kadhim Hayder Adnan Fawzi Shoroq Mohammed Al-Temimi Bassim Mohammad Asma Swadi Source Type: research
Epidemiological profile of hemophilia A in Karbala-Iraq
In this study, one-third of patients' presentations started in the first year of life. The most common type was severe hemophilia A (factor VIII activity < 1%). Consequently, more than half of the patients were treated with factor VIII concentrate. Four patients had hepatitis C, while HIV was confirmed in one patient. The epidemiological or clinical parameters of hemophilia A patients in Karbala seem similar to those in other cities in Iraq. By considering this preliminary data, further comprehensive studies for patients with hemophilia and associated complications in other provinces or cities in Iraq are highly suggest...
Source: Journal of Medicine and Life - February 26, 2024 Category: General Medicine Authors: Inas Muayad Mohammed Ali Ashwaq Ali Hussein Israa Mustafa Salih Al-Musawi Sabeeha Sahib Hadi Hillawi Naus Salih Kadhim Abdulkareem Alaiwi Jasim Source Type: research
