The Confounding Role of Graft-Versus-Host Disease in Animal Models of Cancer Immunotherapy: A Systematic Review
CONCLUSION: By systematically identifying and mitigating the confounding effects of GVHD, we can significantly improve the predictive validity of preclinical trials, obtain broadly applicable findings, improve the efficiency of drugs, enhance safety profiling, and develop better therapeutic strategies. This approach is crucial in ensuring that the immunotherapeutic strategies developed in the laboratory are reflective of the human physiological response, thereby bridging a critical translational gap in oncological research.PMID:38685841 | DOI:10.34172/aim.2024.24 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Hami Ashraf Mohammad Heydarnejad Farid Kosari Source Type: research
Synchronous Double Primary Angiosarcoma Originating from the Stomach and Rectum: A Case Report and a Literature Review
Arch Iran Med. 2024 Mar 1;27(3):168-173. doi: 10.34172/aim.2024.25.ABSTRACTAngiosarcomas originating from the gastrointestinal tract are rare but highly aggressive tumors with poor prognosis. These tumors can be misdiagnosed as benign and malignant gastrointestinal tract lesions. The definitive histological diagnosis of angiosarcomasis made by pathologists based on immunohistochemical analysis demonstrating cluster of differentiation 31 (CD31), factor VIII-related antigen (FVIIIRAg), erythroblast transformation specific related gene (ERG), and cluster of differentiation 34 (CD34). Angiosarcomas are treated with a single or...
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Tanju Kapagan Nilufer Bulut Gokmen Umut Erdem Suleyman Y ıldırım Zeynep Betul Erdem Halil Sahin Source Type: research
Comparing the Emergency Care of Iranian and Afghan Patients During the COVID-19 Pandemic
CONCLUSION: Afghan nationals admitted to the hospital due to traumas were more likely to be admitted to ICUs or die compared to Iranian citizens. It seems that Afghan patients who had traumas went to the hospitals with more serious injuries. There was no difference between Afghan and Iranian patients in terms of COVID-19 consequences. Following the findings of this study, it seems that justice in treatment has been fully established for Afghan patients in Iran.PMID:38685839 | DOI:10.34172/aim.2024.22 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Milad Ahmadi Gohari Maryam Chegeni Mohammad Hossein Mehrolhassani Ali Akbar Haghdoost Moghaddameh Mirzaee Source Type: research
Comparison of the Mental Disorders Among Families of ISIS Captives Residing in Sulaymaniyah With the Native Population in 2023: A Cross-sectional Study
CONCLUSION: The findings of this study suggest that ISIS captives suffer from multiple psychological disorders, and the presence of more severe mental disorders among this population necessitates comprehensive psychiatric and psychological services for them.PMID:38685838 | DOI:10.34172/aim.2024.21 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Bakhtyar Zrar Rahman Mansour Bayrami Khalil Esmaielpour Source Type: research
Prognosis of Methanol Poisoning in a Developing Setting
CONCLUSION: Besides LOC, patients with any abnormality in their brain CT scan on admission were found to be at higher risk of death, and patients with supratentorial edema were at risk of longer LOS. Brain CT-scan on admission should be considered as a part of the routine procedure during the management of methanol-poisoning.PMID:38685837 | DOI:10.34172/aim.2024.20 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Mohammad Reza Sasani Hossein Molavi Vardanjani Zahra Mehdipour Namdar Marjan Jeddi Shiva Seif Sogol Sedighi Seyed Amirreza Akhlagh Dena Firouzabadi Amirreza Dehghanian Source Type: research
Managing Hepatotoxicity Caused by Anti-tuberculosis Drugs: A Comparative Study of Approaches
CONCLUSION: Drug-induced hepatotoxicity is a common occurrence that often results in treatment discontinuation. Understanding the prevalence of this complication and identifying appropriate methods of rechallenge treatment is crucial to reducing complications and mortality rates.PMID:38685836 | DOI:10.34172/aim.2024.19 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Faeze Abbaspour Malihe Hasannezhad Hossein Khalili SeyedAhmad SeyedAlinaghi Sirous Jafari Source Type: research
The Global Road Traffic Death Rate and Human Development Index from 2000 to 2019: A Trend Analysis
CONCLUSION: Overall, this study emphasizes the significance of HDI and its components, particularly education and LE, in lowering the number of traffic fatalities. In this sense, improving formal education and LE could be one of the main policies that policymakers could consider to reduce RTDR.PMID:38685835 | DOI:10.34172/aim.2024.18 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Mohammad Sayari Mohammad Reza Rahmanian Haghighi Kamran Bagheri Lankarani Sulmaz Ghahramani Behnam Honarvar Source Type: research
EBV-Associated Gastric Cancer; An In Situ Hybridization Assay on Tissue Microarray: A Multi-Region Study from Four Major Provinces of Iran
CONCLUSION: EBV-associated gastric adenocarcinoma has a low prevalence in Iran. This finding can be due to epidemiologic differences in risk factors and exposures, and the low number of gastric medullary carcinomas in the population. It may also be related to gastric tumor heterogeneity not detected with the TMA technique.PMID:38685845 | DOI:10.34172/aim.2024.28 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Maryam Abolhasani Ata Ollah Mohseni Ramin Shakeri Ali Khavanin Mehrdad Khajehei Abbasali Omidi Bita Geramizadeh Ensieh Shafigh Farshad Naghshvar Payam Fathizadeh Leyla Taghizadehgan Atoosa Gharib Margaret L Gulley Sanford M Dawsey Reza Malekzadeh Charles Source Type: research
Predictors of Recurrent Urolithiasis in Iran: Findings from a Nationwide Study
CONCLUSION: Our results indicate that a positive family history of urolithiasis in mother and father and residence in urban areas are the significant predictors of recurrence risk in urolithiasis patients in Iran.PMID:38685846 | DOI:10.34172/aim.2024.29 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Abbas Basiri Amir Hossein Kashi Mazyar Zahir Nasrin Borumandnia Maryam Taheri Shabnam Golshan Behzad Narouie Hayat Mombeini Source Type: research
Neoadjuvant Chemotherapy in Patients with HER2-Negative Breast Cancer: A Report from Clinical Breast Cancer Registry of Iran
CONCLUSION: This study provides further evidence that NCT is a viable treatment option for patients with HER2-negative BC. The TAC regimen resulted in a significantly higher pCR rate compared to other regimens, but did not result in a significant improvement in recurrence, OS and DFS and rates.PMID:38685847 | DOI:10.34172/aim.2024.30 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Kamran Roudini Mehrzad Mirzania Tahereh Yavari Monireh Sadat Seyyedsalehi Azin Nahvijou Jayran Zebardast Mina Saadat Ahmad Khajeh-Mehrizi Source Type: research
Clinicopathological Pattern of Endometrial Specimens in Women with Abnormal Uterine Bleeding and Ultrasonography Correlation
CONCLUSION: Endometrial sampling is a useful tool for evaluation of women with AUB and referring patients for treatment. Histopathological evaluation of the endometrium is very useful in detecting the etiology of AUB. Transvaginal sonography has high sensitivity in detecting polyps.PMID:38685848 | DOI:10.34172/aim.2024.31 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Mohadeseh Karimi Anahita Alizadeh Masoumeh Mahmoodi Source Type: research
Identification of a Novel Homozygous Mutation in < em > PRDM12 < /em > Gene in a Patient with Hereditary Sensory and Autonomic Neuropathy Type VIII
Arch Iran Med. 2024 Apr 1;27(4):223-226. doi: 10.34172/aim.2024.32.ABSTRACTHereditary sensory autonomic neuropathy type VIII (HSAN-VIII) is a rare genetic disease that occurs due to mutations in the PRDM12 gene. Here, we describe a novel homozygous mutation c.826_840dupTGCAACCGCCGCTTC (p.Cys276_Phe280dup) on exon 5 in the PRDM12 gene identified by WES and confirmed using Sanger sequencing method.PMID:38685849 | DOI:10.34172/aim.2024.32 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Amir Hossein Ebrahimi Manzar Bolhassani Mohammad Reza Zarei Matin Heidari Amin ArdeshirDavani Amir Hosein Mehrtash Zahra Shiri Masoud Heidari Morteza Soleyman-Nejad Mohammad Hossein Taskhiri Arefeh Norouzbeigi Mansour Heidari Source Type: research
In Memory of Dr. Taba, the Legendary WHO Regional Director
Arch Iran Med. 2024 Apr 1;27(4):227-228. doi: 10.34172/aim.2024.33.ABSTRACTThe article is a tribute to Dr. Abdul-Hossein Tabatabai-Naini, the former Regional Director of the Eastern Mediterranean Regional Office (EMRO), on the occasion of WHO's 75th anniversary. It reports on his achievements, personality, and philosophy of medicine.PMID:38685850 | DOI:10.34172/aim.2024.33 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Yasmine Motarjemi Source Type: research
The association between dietary patterns and metabolic syndrome among Iranian adults, a cross-sectional population-based study (findings from Bandare-Kong non-communicable disease cohort study)
Metabolic syndrome is a cluster of metabolic disorders increasing the risk of cardiovascular disease and diabetes. Dietary patterns are supposed to be important and controllable factors in developing metabolic... (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - April 30, 2024 Category: Endocrinology Authors: Masoumeh Kheirandish, Farideh Dastsouz, Abnoos Azarbad, Mohammad Ali Mohsenpour, Gholamali Javdan, Farkhondeh Razmpour, Seyed Hossein Davoodi, Nahid Ramezani-Jolfaie and Mohammad Mohammadi Tags: Research Source Type: research
Probiotics: truths and illusions
Iran J Microbiol. 2024 Feb;16(1):1-3. doi: 10.18502/ijm.v16i1.14865.NO ABSTRACTPMID:38682066 | PMC:PMC11055431 | DOI:10.18502/ijm.v16i1.14865 (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - April 29, 2024 Category: Microbiology Authors: Sogol Tavanaeian Mohammad Mehdi Feizabadi Source Type: research
