Data management in diabetes clinical trials: a qualitative study
ConclusionAccording to the results, the common methods of data management in diabetes clinical trials included a set of paper-based processes. It seems that using information technology can help facilitate data management processes in a variety of clinical trials, including diabetes clinical trials. (Source: Trials)
Source: Trials - March 3, 2022 Category: Research Source Type: clinical trials
The effects of l-carnitine supplementation on inflammatory factors, oxidative stress, and clinical outcomes in patients with sepsis admitted to the intensive care unit (ICU): study protocol for a double blind, randomized, placebo-controlled clinical trial
DiscussionBecause of the anti-inflammatory and antioxidant properties ofl-carnitine, it is possible that using a high dose of 3000 mg daily of this nutritional supplement may reduce inflammation and oxidative stress and improve subsequent mortality of critically ill patients with sepsis.Trial registrationIranian Registry of Clinical TrialsIRCT20201129049534N1. Registered on 2 May 2021. (Source: Trials)
Source: Trials - February 22, 2022 Category: Research Source Type: clinical trials
Effect of dynamic neuromuscular stabilization on balance and trunk function in people with multiple sclerosis: protocol for a randomized control trial
DiscussionDynamic neurostabilization exercises utilize the subconscious stimulation of special zones to reflexively mediate the diaphragm and other core stabilization muscles, which is extremely effective for individuals with reduced somatosensory or movement awareness. Findings from the proposed study are expected to benefit the knowledge base of the physiotherapist, and it can be a good alternative for the rehabilitation program and even reduce medication use in patients with multiple sclerosis. These exercises are easy to understand and applicable for these patients and their partners as well.Trial registrationThe trial...
Source: Trials - January 21, 2022 Category: Research Source Type: clinical trials
Study protocol of a randomized controlled clinical trial investigating the effects of omega-3 supplementation on endothelial function, vascular structure, and metabolic parameters in adolescents with type 1 diabetes
DiscussionIt is hypothesized that omega-3 supplementation may be beneficial for the management of type 1 diabetes and its complications by reducing inflammation and oxidative stress and also modulating immune responses and glucose and lipid metabolism through various mechanisms. The present study aims to investigate any effect of omega-3 on patients with type 1 diabetes.Ethical aspectsThis trial received approval from Medical Ethics Committee of Iran University of Medical Sciences, Tehran, Iran (IR.IUMS.REC.1400.070).Trial registrationIranian Registry of Clinical TrialsIRCT20210419051010N1. Registered on 29 April 2021 (Source: Trials)
Source: Trials - December 27, 2021 Category: Research Source Type: clinical trials
Effects of naringenin supplementation in overweight/obese patients with non-alcoholic fatty liver disease: study protocol for a randomized double-blind clinical trial
DiscussionWe hypothesize that naringenin administration may be useful for treating NAFLD by modulating energy balance, glucose and lipid metabolism, oxidative stress, and inflammation through different mechanisms. The current trial will exhibit the effects of naringenin, whether negative or positive, on NAFLD status.Ethical aspectsThe current trial received approval from the Medical Ethics Committee of Tehran University of Medical Sciences, Tehran, Iran (IR.TUMS.MEDICNE.REC.1399.439).Trial registrationIranian Registry of Clinical TrialsIRCT201311250155336N12. Registered on 6 June 2020 (Source: Trials)
Source: Trials - November 13, 2021 Category: Research Source Type: clinical trials
Ocular Manifestation and Related Risk Factors of Covid-19 Associated Mucormycosis: a Multicenter Study in Iran
Conditions: COVID-19; Mucormycosis Intervention: Sponsors: Isfahan University of Medical Sciences; Shiraz University of Medical Sciences; Ahvaz Jundishapur University of Medical Sciences; Iran University of Medical Sciences; Mashhad University of Medical Sciences; Tabriz University of Medical Sciences; Guilan University of Medical Sciences; Kermanshah University of Medical Sciences; Shahid Beheshti University of Medical Sciences; Semnan University of Medical Sciences Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 28, 2021 Category: Research Source Type: clinical trials
