Disopyramide in HCM – Cardiology MCQ
Disopyramide is a class Ia antiarrhythmic agent which can be used in hypertrophic obstructive cardiomyopathy when beta blockers alone are ineffective. Pick out the WRONG statement regarding disopyramide in this context:
a) Regular monitoring of QTc is recommended during dose up titration
b) Has a risk of fast ventricular rate in those prone for atrial fibrillation
c) Should not be used in combination with verapamil
d) Should not be combined with other drugs which prolong the QT interval like amiodarone and sotalol
Post your answer as a comment below. Correct answer will be published on: Apr 24, 2018 @ 16:55
The post Disop...
Source: Cardiophile MD - April 22, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: ECG / Electrophysiology ECG Library Source Type: blogs
HCM exercise BP – Cardiology MCQ
Abnormal exercise blood pressure response in hypertrophic obstructive cardiomyopathy has been defined as:
a) Progressive increase in blood pressure upto peak exercise
b) Failure to rise at least 20 mm Hg or fall of at least 20 mm Hg from peak level
c) Fall in blood pressure of 30 mm Hg at the onset of exercise
d) Failure to achieve a peak systolic blood pressure of at least 160 mm Hg
Post your answer as a comment below. Correct answer will be published on: Apr 23, 2018 @ 20:25
The post HCM exercise BP – Cardiology MCQ appeared first on Cardiophile MD. (Source: Cardiophile MD)
Source: Cardiophile MD - April 21, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: General Cardiology Source Type: blogs
Level at which left ventricular outflow gradient becomes hemodynamically significant – Cardiology MCQ – Answer
Level at which left ventricular outflow gradient becomes hemodynamically significant:
Cardiology MCQs from Cardiophile MD
Click here for Volume 2!
Volume 3 to be published soon!
Correct answer: b) 50 mm Hg.
But for defining left ventricular outflow tract obstruction (LVOTO), a peak left ventricular outflow tract (LVOT) pressure gradient of 30 mm Hg or more at rest or during physiological provocative measures like Valsalva manoeuvre, standing or exercise is enough.
Symptomatic patients with LVOTO gradient 50 mm Hg or above in spite of maximally tolerated medications will be considered for septal reduction therapies like s...
Source: Cardiophile MD - April 21, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
Besides the Nonspecific T-wave Inversion in aVL, What Else is Abnormal on this ECG?
This case was sent by Laszlo Farkas, a paramedic from Hungary. He discussed it with Janos Borbas MD and Robert Sepp MD from University of Szeged 2nd Department of Internal Medicine and Cardiology Clinic. The case inspired me to resurrect a case that I published 10 years ago with the same ECG finding (2nd case below).What is the finding?What does it signify?CaseAn elderly male presented with chest pain. Here is the first ED ECG:Hint: the finding is NOT the T-wave inversion in aVLThis ECG that I published 10 years ago in Critical Decisions in Emergency and Acute Care Electrocardiography has th...
Source: Dr. Smith's ECG Blog - April 14, 2018 Category: Cardiology Authors: Steve Smith Source Type: blogs
MyoKardia Develops Machine Learning Algorithm For Prediction of Hypertrophic Cardiomyopathy Using Wearable Biosensor: Interview
In this study, we collected PPG pulse wave traces from patients with oHCM and healthy volunteers. Using automated analyses, we extracted details about the shape and pattern of the tracings and applied machine learning to identify differences in these features between oHCM patients and healthy volunteers. We found that a sensitive and specific signature of arterial blood flow in oHCM could be identified with the combination of a wrist-worn PPG biosensor and machine learning algorithms.
Medgadget: Have you compared the results of the biosensor created by Wavelet Health with results collected from another similar PPG d...
Source: Medgadget - February 8, 2018 Category: Medical Devices Authors: Alice Ferng Tags: Cardiology Exclusive Source Type: blogs
Hypertrophic cardiomyopathy (HCM) FAQs
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - January 23, 2018 Category: Internal Medicine Tags: cardiovascular Source Type: blogs
Hypertrophic cardiomyopathy
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - January 13, 2018 Category: Internal Medicine Tags: cardiovascular Source Type: blogs
Differentiation of supravalvar aortic stenosis from valvar and subvalvular variety
Differentiation of supravalvar aortic stenosis from valvular and subvalvular variety
Murmur
Murmur of subvalvular aortic stenosis is unlikely to radiate to the carotids. Murmur of supravalvar aortic stenosis may radiate more to the right carotid. Murmur of valvular aortic stenosis radiates to both carotids.
Ejection click
Ejection click is in favour valvular aortic stenosis.
Associated aortic regurgitation
Supravalvar aortic stenosis is unlikely to be associated with aortic regurgitation, while it can occur in valvular and subvalvular variety. In fact aortic regurgitation may be seen in almost half of those with subvalvula...
Source: Cardiophile MD - January 10, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: General Cardiology Anisosphygmia Aortic regurgitation Aortic stenosis subvalvar aortic stenosis supravalvar aortic stenosis Source Type: blogs
VCP Discovered to be Important in Cardiac Hypertrophy
Here, researchers investigate the role of the VCP gene in producing cardiac hypertrophy as a response to hypertension, or high blood pressure. Blood vessels become stiff with age, the result of cross-linking, calcification, and dysfunction in the smooth muscle that controls contraction and dilation. This causes hypertension by breaking the finely balanced feedback systems that regulate blood pressure in response to environmental circumstances. Hypertension in turn causes cardiac hypertrophy: heart tissue expands inappropriately to become both larger and weaker. At the end of this road lies death due to heart failure or str...
Source: Fight Aging! - December 29, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Uses of isoprenaline in Cardiology
Isoprenaline is predominantly beta stimulant, a synthetic sympathomimetic amine. Is the isopropyl derivative of norepinephrine. Main use in Cardiology is to enhance the heart rate. It is useful in severe bradycardia where its effect can be titrated by setting up an infusion. Sometimes it can produce hypotension due to systemic vasodilation. It has pulmonary vasodilatory effects as well. Isoprenaline infusion can be used in congenital and acquired complete heart blocks to increase the ventricular rate when pacing is not immediately feasible.
Isoprenaline challenge has been used during hemodynamic studies in cathlab to induc...
Source: Cardiophile MD - December 14, 2017 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology Source Type: blogs
Ethics, Morality and Genomic Science: Can We Play God the Way God Plays God?
Richard Payne, MDThe wisdom of humans tinkering with nature has been challenged throughout the ages based on a common storyline: humans unwisely tamper with nature with disastrous consequences for the creator when we cross a line previously reserved for the deity. Three decades ago, in the early days of gene engineering, scientists raised ethical and moral concerns about “playing God.” They weren’t opposed to interrupting the natural order to cross breed animals and plants or to cure or treat disease. Rather, they warned against exercising the power of science and technology without sufficient regard for ...
Source: blog.bioethics.net - December 11, 2017 Category: Medical Ethics Authors: Practical Bioethics Tags: Health Care CRISPR-Cas9 Genomic Science germline gene editing syndicated Source Type: blogs
Cardiology MCQ Test 4
Time limit: 0
Quiz-summary
0 of 20 questions completed
Questions:
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
...
Source: Cardiophile MD - October 21, 2017 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Cardiology MCQ Test 3
Time limit: 0
Quiz-summary
0 of 20 questions completed
Questions:
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
...
Source: Cardiophile MD - October 20, 2017 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Hypertrophic cardiomyopathy mutation corrected in embryo
In a pathbreaking proof of concept experimental study, MYBPC3 gene mutation causing hypertrophic cardiomyopathy has been corrected in human embryos using CRISPR-Cas9 gene editing technique. Study published in Nature [1] from Oregon Health & Science University, Portland, USA showed successful repair of the defective gene by cutting off the mutant sequence using CRISPR–Cas9. Embryos which were heterozygous for the mutation repaired the DNA break using the normal copy from the other parent. There were no off target mutations induced in the process. As always, ethical issues have to be addressed on whether herita...
Source: Cardiophile MD - October 11, 2017 Category: Cardiology Authors: Johnson Francis Tags: Cardiology cardiovascular magenetic resonance imaging CRISPR-Cas9 gene editing technique Hypertrophic cardiomyopathy MYBPC3 Source Type: blogs
MKSAP: 28-year-old pregnant woman with a cardiac murmur
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 28-year-old pregnant woman is evaluated for a cardiac murmur identified on examination by her obstetrician. She is asymptomatic. She is in her 24th week of pregnancy. Medical history is unremarkable, and there is no family history of heart disease. She takes prenatal vitamins and no other medications.
On physical examination, she is afebrile, blood pressure is 120/70 mm Hg, pulse rate is 86/min, and respiration rate is 18/min. Cardiac examination reveals a midsystolic ejection click followed by a grade 3/6 ear...
Source: Kevin, M.D. - Medical Weblog - June 24, 2017 Category: General Medicine Authors: < a href="http://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Heart Source Type: blogs
