Equilibrative nucleotide transporter ENT3 (SLC29A3): A unique transporter for inherited disorders and cancers
Exp Cell Res. 2023 Dec 15:113892. doi: 10.1016/j.yexcr.2023.113892. Online ahead of print.ABSTRACTAs a crucial gene associated with diseases, the SLC29A3 gene encodes the equilibrative nucleoside transporter 3 (ENT3). ENT3 plays an essential regulatory role in transporting intracellular hydrophilic nucleosides, nucleotides, hydrophilic anticancer and antiviral nucleoside drugs, energy metabolism, subcellular localization, protein stability, and signal transduction. The mutation and inactivation of SLC29A3 are intimately linked to the occurrence, development, and prognosis of various human tumors. Moreover, many hereditary ...
Source: Experimental Cell Research - December 17, 2023 Category: Cytology Authors: Hongyin Ma Jian Qu Yongkang Liao Linxin Liu Min Yan Yiwen Wei Weixin Xu Jian Luo Yuxin Dai Zicheng Pang Qiang Qu Source Type: research

Equilibrative nucleotide transporter ENT3 (SLC29A3): A unique transporter for inherited disorders and cancers
Exp Cell Res. 2023 Dec 15:113892. doi: 10.1016/j.yexcr.2023.113892. Online ahead of print.ABSTRACTAs a crucial gene associated with diseases, the SLC29A3 gene encodes the equilibrative nucleoside transporter 3 (ENT3). ENT3 plays an essential regulatory role in transporting intracellular hydrophilic nucleosides, nucleotides, hydrophilic anticancer and antiviral nucleoside drugs, energy metabolism, subcellular localization, protein stability, and signal transduction. The mutation and inactivation of SLC29A3 are intimately linked to the occurrence, development, and prognosis of various human tumors. Moreover, many hereditary ...
Source: Experimental Cell Research - December 17, 2023 Category: Cytology Authors: Hongyin Ma Jian Qu Yongkang Liao Linxin Liu Min Yan Yiwen Wei Weixin Xu Jian Luo Yuxin Dai Zicheng Pang Qiang Qu Source Type: research

Oral Minoxidil Therapy in Hair Loss: Where Do We Stand?
AbstractPurpose of ReviewThis review is aimed at elucidating the efficacy and safety of oral minoxidil (OM) for the treatment of hair loss (HL), especially androgenic alopecia (AGA), and at highlighting its future applications. A comprehensive review of the published literature concerning the management of various types of non-scarring HL was performed. The review focused on the therapeutic role of minoxidil (MNX) in HL for both sexes and various age groups.Recent FindingsRecent studies suggested the effectiveness of OM in the dose range of 0.625 –2.5 mg daily and in male pattern hair loss (MPHL), with gradual increase ...
Source: Current Dermatology Reports - November 20, 2023 Category: Dermatology Source Type: research

Low dose oral minoxidil and the conundrum of cardiovascular complications
This article highlights potential clinical conundrums posed by these rare but severe cardiovascular complications and the importance of collaboration between cardiologists and dermatologists when employing this agent in patients with cardiorenal or cardiovascular risk factors.PMID:37921812 | DOI:10.5070/D329461861 (Source: Dermatol Online J)
Source: Dermatol Online J - November 3, 2023 Category: Dermatology Authors: Marina Kristy Ibraheim Ashley Elsensohn Christopher Hauschild Anthony Hilliard Harry Dao Source Type: research

Low dose oral minoxidil and the conundrum of cardiovascular complications
This article highlights potential clinical conundrums posed by these rare but severe cardiovascular complications and the importance of collaboration between cardiologists and dermatologists when employing this agent in patients with cardiorenal or cardiovascular risk factors.PMID:37921812 | DOI:10.5070/D329461861 (Source: Dermatol Online J)
Source: Dermatol Online J - November 3, 2023 Category: Dermatology Authors: Marina Kristy Ibraheim Ashley Elsensohn Christopher Hauschild Anthony Hilliard Harry Dao Source Type: research

Low dose oral minoxidil and the conundrum of cardiovascular complications
This article highlights potential clinical conundrums posed by these rare but severe cardiovascular complications and the importance of collaboration between cardiologists and dermatologists when employing this agent in patients with cardiorenal or cardiovascular risk factors.PMID:37921812 | DOI:10.5070/D329461861 (Source: Dermatol Online J)
Source: Dermatol Online J - November 3, 2023 Category: Dermatology Authors: Marina Kristy Ibraheim Ashley Elsensohn Christopher Hauschild Anthony Hilliard Harry Dao Source Type: research

Low dose oral minoxidil and the conundrum of cardiovascular complications
This article highlights potential clinical conundrums posed by these rare but severe cardiovascular complications and the importance of collaboration between cardiologists and dermatologists when employing this agent in patients with cardiorenal or cardiovascular risk factors.PMID:37921812 | DOI:10.5070/D329461861 (Source: Dermatol Online J)
Source: Dermatol Online J - November 3, 2023 Category: Dermatology Authors: Marina Kristy Ibraheim Ashley Elsensohn Christopher Hauschild Anthony Hilliard Harry Dao Source Type: research

Low dose oral minoxidil and the conundrum of cardiovascular complications
This article highlights potential clinical conundrums posed by these rare but severe cardiovascular complications and the importance of collaboration between cardiologists and dermatologists when employing this agent in patients with cardiorenal or cardiovascular risk factors.PMID:37921812 | DOI:10.5070/D329461861 (Source: Dermatol Online J)
Source: Dermatol Online J - November 3, 2023 Category: Dermatology Authors: Marina Kristy Ibraheim Ashley Elsensohn Christopher Hauschild Anthony Hilliard Harry Dao Source Type: research

Low dose oral minoxidil and the conundrum of cardiovascular complications
This article highlights potential clinical conundrums posed by these rare but severe cardiovascular complications and the importance of collaboration between cardiologists and dermatologists when employing this agent in patients with cardiorenal or cardiovascular risk factors.PMID:37921812 | DOI:10.5070/D329461861 (Source: Dermatol Online J)
Source: Dermatol Online J - November 3, 2023 Category: Dermatology Authors: Marina Kristy Ibraheim Ashley Elsensohn Christopher Hauschild Anthony Hilliard Harry Dao Source Type: research

Low dose oral minoxidil and the conundrum of cardiovascular complications
This article highlights potential clinical conundrums posed by these rare but severe cardiovascular complications and the importance of collaboration between cardiologists and dermatologists when employing this agent in patients with cardiorenal or cardiovascular risk factors.PMID:37921812 | DOI:10.5070/D329461861 (Source: Dermatol Online J)
Source: Dermatol Online J - November 3, 2023 Category: Dermatology Authors: Marina Kristy Ibraheim Ashley Elsensohn Christopher Hauschild Anthony Hilliard Harry Dao Source Type: research

Low dose oral minoxidil and the conundrum of cardiovascular complications
This article highlights potential clinical conundrums posed by these rare but severe cardiovascular complications and the importance of collaboration between cardiologists and dermatologists when employing this agent in patients with cardiorenal or cardiovascular risk factors.PMID:37921812 | DOI:10.5070/D329461861 (Source: Dermatol Online J)
Source: Dermatol Online J - November 3, 2023 Category: Dermatology Authors: Marina Kristy Ibraheim Ashley Elsensohn Christopher Hauschild Anthony Hilliard Harry Dao Source Type: research

Low dose oral minoxidil and the conundrum of cardiovascular complications
This article highlights potential clinical conundrums posed by these rare but severe cardiovascular complications and the importance of collaboration between cardiologists and dermatologists when employing this agent in patients with cardiorenal or cardiovascular risk factors.PMID:37921812 | DOI:10.5070/D329461861 (Source: Dermatol Online J)
Source: Dermatol Online J - November 3, 2023 Category: Dermatology Authors: Marina Kristy Ibraheim Ashley Elsensohn Christopher Hauschild Anthony Hilliard Harry Dao Source Type: research

Low dose oral minoxidil and the conundrum of cardiovascular complications
This article highlights potential clinical conundrums posed by these rare but severe cardiovascular complications and the importance of collaboration between cardiologists and dermatologists when employing this agent in patients with cardiorenal or cardiovascular risk factors.PMID:37921812 | DOI:10.5070/D329461861 (Source: Dermatol Online J)
Source: Dermatol Online J - November 3, 2023 Category: Dermatology Authors: Marina Kristy Ibraheim Ashley Elsensohn Christopher Hauschild Anthony Hilliard Harry Dao Source Type: research

Low dose oral minoxidil and the conundrum of cardiovascular complications
This article highlights potential clinical conundrums posed by these rare but severe cardiovascular complications and the importance of collaboration between cardiologists and dermatologists when employing this agent in patients with cardiorenal or cardiovascular risk factors.PMID:37921812 | DOI:10.5070/D329461861 (Source: Dermatol Online J)
Source: Dermatol Online J - November 3, 2023 Category: Dermatology Authors: Marina Kristy Ibraheim Ashley Elsensohn Christopher Hauschild Anthony Hilliard Harry Dao Source Type: research