Protein Aggregation in the Aging Heart
As noted in this open access paper, protein misfolding and aggregation is a body-wide feature of aging, not only associated with the brain and neurodegenerative conditions. In the case of the heart, it is becoming apparent that misfolding of transthyretin to form amyloid can play a role in heart disease, and this form of amyloidosis may grow to be the majority cause of death for supercentenarians. The paper here is a more general tour of relevant mechanisms rather than a focus on any one specific protein, but is nonetheless interesting.
Protein homeostasis, the balance between protein synthesis and degradation, re...
Source: Fight Aging! - May 5, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Advantages of Left ventricular hypertrophy (LVH)
This is a 15-year-old post about LVH, written in 2008. Few of my colleagues, now agree with this, but still hesitate to oblige in the open, suggesting it is too good to be true! Re-posting it for your own assessment. Surprised, why cardiology community didn’t consider this observation worthy to pursue.
Advantages of Left ventricular hypertrophy (LVH)
Left ventricular hypertrophy is one of the most common clinical cardiac entity.It is recognised either by ECG or echocardiography.LVH has a unique place in cardiology as it can imply a grossly pathological state or a marker of healthy heart as in physiologica...
Source: Dr.S.Venkatesan MD - May 4, 2023 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Source Type: blogs
High Blood Pressure: An Undetected Danger Among England ’ s Youth
Conclusion: Taking Action for a Healthier Future
The issue of undiagnosed high blood pressure among England’s youth is a pressing concern.
Early detection and intervention are essential to prevent long-term health complications and reduce the risk of heart attacks and strokes.
As Dr. Swift emphasizes:
“Educating young people about the risks associated with high blood pressure and promoting healthy lifestyle choices from an early age is crucial in tackling this growing health issue.”
To safeguard the well-being of future generations, it is vital to raise awareness about the importance of...
Source: The EMT Spot - May 4, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
How To Choose The Best Supplement For Your Blood Pressure Condition?
Conclusion
To sum up, natural supplements have become popular for controlling high blood pressure due to their perceived safety compared to prescription medications, which often cause unpleasant side effects.
Prioritizing your health is essential, and seeking medical advice before taking any supplements is especially crucial, particularly if you struggle with comorbidity, pregnancy, or breastfeeding.
When choosing a blood pressure supplement, consider the ingredients, dosage, brand reputation, and cost.
Remember that supplements are not a substitute for a healthy lifestyle that includes a balanced diet, regular...
Source: The EMT Spot - May 3, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Supplements Source Type: blogs
Do Blood Pressure Supplements Interact With Any Foods Or Drinks?
Conclusion
To sum things up, blood pressure supplements are a safe and effective option for managing hypertension, and they typically do not interact with most foods and drinks.
However, some fruits and beverages may reduce the effectiveness of natural supplements. To ensure that you receive the maximum benefit from your blood pressure supplements, avoiding certain foods and drinks is essential.
Licorice, grapefruit, and alcohol are among the top culprits that can interfere with the efficacy of supplements and cause negative side effects.
High-fat meals and salt substitutes containing potassium can also hinder ...
Source: The EMT Spot - May 3, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Supplements Source Type: blogs
Science Snippet: The Power of Proteins
Some might think that protein is only important for weightlifters. In truth, all life relies on the activity of protein molecules. A single human cell contains thousands of different proteins with diverse roles, including:
Actin proteins in a cell’s cytoskeleton. Credit: Xiaowei Zhuang, HHMI, Harvard University, and Nature Publishing Group.
Providing structure. Proteins such as actin make up the three-dimensional cytoskeleton that gives cells structure and determines their shapes.
Aiding chemical reactions. Many proteins are biological catalysts called enzymes that speed up the rate of chemical reactions by redu...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - May 3, 2023 Category: Research Authors: Chrissa Chverchko Tags: Cells Molecular Structures Cellular Processes Medicines Proteins Science Snippet Source Type: blogs
Cuffless Blood Pressure Monitoring – Not for the Faint-of-Heart (Pun Intended)
This article will summarize these challenges and also provide optimism for the refreshingly near future. Namely, while the progress towards FDA-cleared cuffless BP monitoring may feel protracted, significant technological advances, regulatory modernization, and clinical use case validation are rapidly advancing and aligning.
Key Challenges Confronting OTC Cuffless Blood Pressure Monitoring
Scientific Risks
At the most fundamental level, the jury’s still out on whether sufficiently accurate noninvasive, cuffless, calibration-free blood pressure monitoring is physically realizable at all. Namely, “Do the laws of nature...
Source: EMR and HIPAA - May 3, 2023 Category: Information Technology Authors: Guest Author Tags: Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Telemedicine and Remote Monitoring AliveCor Blood Pressure Blood Pressure Cuffs Blood Pressure Monitoring BP Calibration-Free Bloo Source Type: blogs
Workplace Discrimination: The Surprising Cause Of High Blood Pressure
Conclusion: The Urgent Need To Combat Workplace Discrimination And Its Health Consequences
In conclusion, the study’s findings emphasize the alarming link between workplace discrimination and high bp, shedding light on the detrimental effects discrimination can have on employees’ physical health.
The research underscores the urgent need for employers to create and enforce anti-discriminatory policies and cultivate inclusive work environments.
Healthcare professionals should also play an active role in addressing this issue by asking patients about their work experiences and potential discrimination t...
Source: The EMT Spot - May 2, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
Finally A Good Wearable Blood Pressure Monitor: Aktiia Bracelet Review
The digital health revolution has been lagging behind in at least one major field: blood pressure monitoring. For a very long time, there were no better solutions in the market than traditional cuffs. Even the first smartwatches (like the one I tested from Omron), were big and uncomfortable to wear. So it was time for companies to realise the future of BP monitoring lies in Photoplethysmography (PPG).
PPG is a non-invasive optical technique used to measure blood volume changes in the microvascular bed of tissue. It works by shining a light onto the skin and then measuring the variations in light intensity that result fr...
Source: The Medical Futurist - May 2, 2023 Category: Information Technology Authors: Andrea Koncz Tags: Health Sensors & Trackers Aktiia review blood pressure wearable blood pressure monitor non-invasive blood pressure monitor blood pressure bracelet digital health sensors Source Type: blogs
What Are The Benefits Of Blood Pressure Lowering Pills?
Conclusion
In conclusion, natural blood pressure lowering supplements are a safe and effective way to manage hypertension without the unpleasant side effects of prescription drugs.
They are made from natural ingredients and are believed to improve blood flow and lower blood pressure.
However, natural supplements cannot replace prescription drugs for dangerously high blood pressure, and consultation with a doctor is crucial before making any changes to your blood pressure management plan.
Combining natural supplements with a healthy lifestyle can provide a holistic approach to managing blood pressure.
It̵...
Source: The EMT Spot - May 1, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Supplements Source Type: blogs
A woman in her 60s with large T-waves. Are they hyperacute, hyperkalemic, or something else?
Case written by Brandon Friedman M.D., edits by MeyersA woman in her 60s with a history of chronic atrial fibrillation on Eliquis, ESRD on hemodialysis, type-II diabetes mellitus, prior CVA, hypertension, and hyperlipidemia presented to the emergency department with multiple complaints after missing dialysis. She described a feeling of general unwellness, diarrhea, right-sided abdominal pain, bilateral leg pain, bilateral leg swelling, and diffuse itching. She missed her last two dialysis appointments, with her last session occurring one week prior to presentation. On initial assessment, she was found to be tachycard...
Source: Dr. Smith's ECG Blog - May 1, 2023 Category: Cardiology Authors: Pendell Source Type: blogs
How To Monitor Your Blood Pressure While Using A Blood Pressure Supplement?
Conclusion
In conclusion, if you are managing your high blood pressure with natural supplements, routine monitoring of your blood pressure is crucial.
Natural supplements can interact with other medications or health conditions, and their effectiveness can vary from person to person.
Regular monitoring of your blood pressure can help detect adverse effects early on, track the effectiveness of the supplement, and determine if any dosage adjustments are necessary.
Purchasing a reliable home blood pressure monitor, following the instructions carefully, taking readings at the same time each day, and keeping track o...
Source: The EMT Spot - April 30, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Supplements Source Type: blogs
Aiming for Health Equity
The following is a guest article by Hakim Yadi, PhD OBE, Co-Founder and CEO at Closed Loop Medicine
Healthcare has historically taken a ‘one size fits all’ approach, which misses the ability to treat all patients as effectively and equitably as possible. Consequently, personalized medicine where treatments are better tailored to a patient has become an aspiration of the modern healthcare system. However, when we look at existing medicines used today, drug therapy is rarely dose optimized for the individual, with most therapies and medical devices approved based on overall safety and efficacy investigated in large-scale...
Source: EMR and HIPAA - April 24, 2023 Category: Information Technology Authors: Guest Author Tags: Analytics/Big Data C-Suite Leadership Health IT Company Healthcare IT Closed Loop Medicine Digital Healthcare Hakim Yadi PhD OBE Health Equity Hypertension Patient Health Outcomes Personalized Care Personalized Medicine Racial Disp Source Type: blogs
Scene Health Secures $17.7 Million Series B Financing Led by ABS Capital Partners
Funding Will Grow Medication Adherence Services for Medicaid and Other Under-Resourced Populations
Scene Health, the leading medication engagement company, has closed an oversubscribed $17.7 million Series B growth financing led by ABS Capital Partners with participation from existing investors Claritas Health Ventures, as well as Healthworx, the innovation and investment arm of CareFirst BlueCross BlueShield, PTX Capital, and Kapor Capital.
The investment is the latest validation of Scene Health’s unique video-based platform, which empowers people to take medication properly through person-to-person connections, ...
Source: EMR and HIPAA - April 21, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT ABS Capital Partners Cal Wheaton CareFirst BlueCross BlueShield Chronic Conditions Claritas Health Ventures Health IT Funding Health IT Fundings Health IT Investment Healthworx Kapor Capital Medicai Source Type: blogs
Compare these two ECGs. Do either, neither, or both show anything important?
One case sent by Dr. Sean Rees MD, written by Pendell Meyers, other case by Sam Ghali and Steve SmithTake a look at these two ECGs below from two patients in the ED, first without any clinical context. Full case details and outcomes are below.Case 1:Case 2: Case 1:What do you think?This was sent to Dr. Smith by SamGhali (@EM_RESUS) with zero other info. Smith ' s response was: " OMI Mimic. "Later, this info was supplied by Sam:This
ECG was recorded in a 23-year-old African American man with a history
of psychiatric illness, acute alcohol/drug intoxication, brought in by
police officers status post being ...
Source: Dr. Smith's ECG Blog - April 17, 2023 Category: Cardiology Authors: Pendell Source Type: blogs
