TWiV 1001: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses an update on vaccine-derived poliovirus outbreaks, how the dream of wiping out polio might need a rethink, risk of death in patients hospitalized for COVID-19 vs seasonal Influenza in fall-winter, French Mpox cluster includes fully vaccinated patients, two individuals with potential Mpox virus reinfection, epidemiologic and clinical features of Mpox-associated deaths, FDA authorizes changes to simplify use of bivalent mRNA COVID-19 vaccines, SARS-CoV-2 during Omicron variant predominance among infants born to people with SARS-CoV-2, severe maternal morbidity and mortalit...
Source: This Week in Virology - MP3 Edition - April 23, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 996: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses how antibiotics don’t reduce risk of death from viral respiratory infections, norovirus infections continue to rise in the US, ABO blood types and SARS-CoV-2 infection assessed using seroprevalence data in a large population-based sample, maternal third dose of BNT162b2 mRNA vaccine and risk of infant COVID-19 hospitalization, association of treatment with Nirmatrelvir and the risk of Post–COVID-19 condition, mechanically ventilated patients with COVID-19 had a higher chance of in-hospital death if treated with high-flow nasal cannula oxygen before intubation, high-f...
Source: This Week in Virology - MP3 Edition - April 1, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Trends in Pediatric Mental Health Hospitalizations
Mary Arakelyan, MPH, and JoAnna Leyenaar, MD, PhD, MPH, vice chair of Research in Pediatrics at Dartmouth, discuss increases in pediatric mental health hospitalizations and suicide-related diagnoses over the past decade. Hosted by JAMA Associate Editor Tracy Lieu, MD, MPH. Related Content: Pediatric Mental Health Hospitalizations at Acute Care Hospitals in the US, 2009-2019. Related Content: Pediatric Mental Health Hospitalizations at Acute Care Hospitals in the US, 2009-2019 (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - March 28, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 994: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the detection of circulating vaccine-derived poliovirus type 2 in Burundi and the Democratic Republic of the Congo, the novel oral polio vaccine type 2 story, prior COVID-19 infection associated with increased risk of newly diagnosed erectile dysfunction, adverse maternal, fetal, and newborn outcomes among pregnant women with SARS-CoV-2 infection, correlates of protection against COVID-19 infection and intensity of symptomatic disease in vaccinated individuals exposed to SARS-CoV-2 in households in Israel, effectiveness of Nirmatrelvir–Ritonavir in preventing hospital ...
Source: This Week in Virology - MP3 Edition - March 25, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Nappuccinos and circadian rhythms
Fatigue can have as much of an affect in your ability to function as alcohol, and yet while you would be chastised for drinking before appearing on the ward, hospitals have systematically removed the spaces where tired clinicians can rest and recover. The Royal College of Anaesthetists have been campaigning to raise awareness of the dangers of fatigue, and it seems that anaesthetic trainees have benefitted from that, with sleep pods and flexible schedules - but other specialties are lagging behind. In this podcast, Roo McCrossan, a consultant anaesthetist joins our host Clara Munro, a surgical trainee, and Ayesha Ashmore...
Source: The BMJ Podcast - March 24, 2023 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

Nappuccinos and circadian rhythms
Fatigue can have as much of an affect in your ability to function as alcohol, and yet while you would be chastised for drinking before appearing on the ward, hospitals have systematically removed the spaces where tired clinicians can rest and recover. The Royal College of Anaesthetists have been campaigning to raise awareness of the dangers of fatigue, and it seems that anaesthetic trainees have benefitted from that, with sleep pods and flexible schedules - but other specialties are lagging behind. In this podcast, Roo McCrossan, a consultant anaesthetist joins our host Clara Munro, a surgical trainee, and Ayesha Ashmore...
Source: The BMJ Podcast - March 24, 2023 Category: General Medicine Authors: BMJ Group Source Type: podcasts

SCCM Pod-471: Mitigating Diagnostic Delays and Errors With Emphasis on Sepsis
Diagnostic delays and errors are significant contributors to patient illness, injury, and death in the United States. According to the Society to Improve Diagnosis in Medicine, diagnostic errors impact nearly 12 million Americans every year, leading to prolonged hospital stays, increased nonreimbursed healthcare costs, and even more harm when combined with other medical errors. Maureen Madden, DNP, RN, CPNP-AC, CCRN, FCCM, is joined by Mary Jo C. Grant, ACNP, PhD, FAAN, to discuss how to reduce diagnostic delays and errors, with an emphasis on sepsis. This podcast is funded by the Gordon and Betty Moore Foundation through ...
Source: SCCM PodCast - iCritical Care - March 8, 2023 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts

What are the benefits and risks of medication reviews for hospitalised adults?
Several strategies are used to monitor and optimise the use of drugs for hospitalised patients and the Cochrane review of medication review was updated in January 2023. In this podcast, one of the group ’s researchers, Mikkel Christensen, talks with lead author Cille Bülow, both from Copenhagen University Hospital in Denmark, about their latest findings. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - March 6, 2023 Category: General Medicine Authors: Cochrane Source Type: podcasts

Diagnostic Errors in the Emergency Department: A System Solution Is Needed
In this JAMA author interview, Peter J. Pronovost, MD, PhD, Chief Quality & Clinical Transformation Officer, University Hospitals, Cleveland, and an internationally recognized expert in patient safety, discusses his recent article in JAMA on “Misdiagnosis in the Emergency Department.” A new report from AHRQ underscores the seriousness of this problem. Related Content: Misdiagnosis in the Emergency Department (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - February 28, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 986: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the efficacy and safety of two RSV vaccines in older adults, health care vaccine mandate remains as some push for an end, past SARS-CoV-2 infection protection against re-infection, a third vaccine dose equalizes the levels of effectiveness and immunogenicity of heterologous or homologous COVID-19 vaccine regimens, Sotrovimab retains activity against SARS-CoV-2 Omicron variant BQ.1.1 in a non-human primate model, effect of higher-dose Ivermectin for 6 Days vs placebo on time to sustained recovery in outpatients with COVID-19, viral burden rebound in hospitalized patients ...
Source: This Week in Virology - MP3 Edition - February 25, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 984: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the political polarization of COVID-19 treatments among physicians and laypeople in the United States, seven alternatives to evidence-based medicine, Malawi’s cholera death toll crosses 1,300 in its deadliest outbreak on record, impact of coronavirus infections on pediatric patients at a tertiary pediatric hospital, maternal mRNA COVID-19 vaccination during pregnancy and delta or omicron infection or hospital admission in infants, yes masks reduce the risk of spreading infection, despite a review saying they don’t, COVID-19 and airborne transmission: science rejected,...
Source: This Week in Virology - MP3 Edition - February 18, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Are corticosteroids (anti-inflammatory medicines) given orally or by injection an effective treatment for people with COVID-19?
Cochrane has produced a series of reviews relevant to the COVID-19 pandemic and is keeping these up-to-date in light of new evidence. In November 2022, we published the second version of a living systematic review on systemic corticosteroids and, in this podcast, the first authors, Mirko Griesel of the University of Leipzig Medical Center and Carina Wagner of the University Hospital in Cologne in Germany, talk about the evidence they ’ve found and the potential effects of these drugs. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - February 13, 2023 Category: General Medicine Authors: Cochrane Source Type: podcasts

Xpert Ultra for diagnosing tuberculosis and rifampicin resistance in children
Most Cochrane Reviews look at the effects of interventions on health, but a growing number provide evidence on how to diagnose a disease. In September 2022, one of these diagnostic test accuracy reviews was updated for a test used to detect tuberculosis in children. The lead author, Alex Kay (left), and co-author, Tara Ness, from the Texas Children ’s Hospital in Houston in the USA, tell us about the importance of the review and its latest findings in this podcast. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - January 20, 2023 Category: General Medicine Authors: Cochrane Source Type: podcasts

SCCM Pod-469 CCM: Method or Madness? Epidemiology of ICU-Onset Bloodstream Infection
Bloodstream infections (BSIs) acquired in the ICU are potentially preventable. Kyle B. Enfield, MD, FSHEA, FCCM, is joined by Sameer S. Kadri-Rodriguez, MD, MS, to discuss the article, Epidemiology of ICU-Onset Bloodstream Infection: Prevalence, Pathogens, and Risk Factors Among 150,948 ICU Patients at 85 U.S. Hospitals, (Gouel-Cheron A, et al. Crit Care Med. 2022;50:1725-1736). Dr. Kadri-Rodriguez is a critical care and infectious diseases physician at the National Institutes of Health Clinical Center in Bethesda, Maryland. This podcast is sponsored by Sound Physicians. (Source: SCCM PodCast - iCritical Care)
Source: SCCM PodCast - iCritical Care - December 29, 2022 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts

SCCM Pod-467 PCCM: AHA Guidelines Address Calcium During Pediatric Cardiopulmonary Arrest
The American Heart Association's (AHA) cardiopulmonary resuscitation guidelines recommend against the routine administration of IV calcium during pediatric cardiopulmonary arrest because of its association with worse outcomes. However, IV calcium is routinely used in children with heart disease who have cardiopulmonary arrest. Maureen A. Madden, DNP, RN, CPNP-AC, CCRN, FCCM, is joined by Gurpreet S. Dhillon, MD, to discuss the article, Calcium Administration During Cardiopulmonary Resuscitation for In-Hospital Cardiac Arrest in Children With Heart Disease is Associated With Worse Survival - A Report From the American Heart...
Source: SCCM PodCast - iCritical Care - December 21, 2022 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts