Hormone Resistant Prostate Cancer Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Wine Polyphenols Exert Antineoplasic Effect on Androgen Resistant PC-3 Cell Line Through the Inhibition of the Transcriptional Activity of COX-2 Promoter Mediated by NF-kβ
CONCLUSIONS: Polyphenols inhibit transcriptional activity of COX-2 promoter mediated by NF-kβ. This effect could explain, at least in part, the induction of apoptosis in vitro by these substances in castration resistant PCa. PMID: 24836925 [PubMed - as supplied by publisher] (Source: Actas Urologicas Espanolas)
Source: Actas Urologicas Espanolas - May 13, 2014 Category: Urology & Nephrology Authors: Ferruelo A, de Las Heras MM, Redondo C, Ramón de Fata F, Romero I, Angulo JC Tags: Actas Urol Esp Source Type: research

Activity of abiraterone in rechallenging two AR-expressing salivary gland adenocarcinomas, resistant to androgen-deprivation therapy.
In conclusion, second line activity of ADT in AR-expressing, adenocarcinoma, NOS of salivary glands further strengthens the pathogenic and therapeutic role of AR signaling in AR-positive SGCs. PMID: 24618694 [PubMed - as supplied by publisher] (Source: Cancer Biology and Therapy)
Source: Cancer Biology and Therapy - March 11, 2014 Category: Cancer & Oncology Authors: Locati LD, Perrone F, Cortelazzi B, Imbimbo M, Bossi P, Potepan P, Civelli E, Rinaldi G, Quattrone P, Licitra L, Pilotti S Tags: Cancer Biol Ther Source Type: research

The role of IL-6 in the radiation response of prostate cancer
Conclusion: These data demonstrate that IL-6 is important in the biological sequelae following irradiation. Therefore, treatment with concurrent IL-6 inhibition is a potential therapeutic strategy for increasing the radiation response of prostate cancer. (Source: Radiation Oncology)
Source: Radiation Oncology - June 27, 2013 Category: Cancer & Oncology Authors: Chun-Te WuMiao-Fen ChenWen-Cheng ChenChing-Chuan Hsieh Source Type: research

Re: 11C-Choline PET/CT in Patients with Hormone-Resistant Prostate Cancer Showing Biochemical Relapse After Radical Prostatectomy
F. Ceci, P. Castellucci, M. Mamede, R. Schiavina, D. Rubello, C. Fuccio, V. Ambrosini, S. Boschi, G. Martorana and S. Fanti Nuclear Medicine Unit, Department of Haematology, Oncology and Laboratory Medicine, Azienda Ospedaliero-Universitaria di Bologna, Policlinico Sant'Orsola-Malpighi, University of Bologna, Bologna, Italy (Source: The Journal of Urology)
Source: The Journal of Urology - March 7, 2013 Category: Urology & Nephrology Authors: Samir S. Taneja Tags: Urological Oncology: Prostate Cancer Source Type: research

Denosumab osteonecrosis of the mandible: A new entity?A case report
Abstract: In the treatment of osteoporosis, M. Kahler and bone metastases from prostate and breast cancer bisphosphonates play a major role. Not all patients respond well to bisphosphonate treatment. Since a few years adverse effects of these drugs have been reported. A new drug, denosumab, a fully human monoclonal antibody to RANKL, has recently been developed. This case reports a 74-year-old male patient with a medical history of diabetes mellitus, angina pectoris, coronary bypasses, hypertension, and prostate cancer with multiple metastases to lymph nodes, bone and lungs. The prostate cancer was treated according to the...
Source: Journal of Cranio-Maxillofacial Surgery - December 20, 2012 Category: ENT & OMF Authors: Sarina E.C. Pichardo, Sophie C.C. Kuypers, J.P. Richard van Merkesteyn Source Type: research