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Association between third molar and mandibular angle fracture: a systematic review and Meta-analysis
The aim of this study was to investigate the risk of mandibular angle fracture associated with the presence of a mandibular third molar and its position when the mandibular fracture occurs. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - January 17, 2018 Category: ENT & OMF Authors: Francesco Giovacchini, Daniele Paradiso, Caterina Bensi, Stefano Belli, Giuseppe Lomurno, Antonio Tullio Tags: Review Source Type: research

Investigation of cancer associated fibroblasts and p62 expression in oral cancer before and after chemotherapy
The aim of this study is to investigate the expression of the autophagy protein p62 in oral squamous cell carcinoma (OSCC) cells before and after chemotherapy. We also detected cancer-associated fibroblasts (CAFs) in these OSCC samples to explore the roles of p62 and CAFs in chemotherapy. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - January 12, 2018 Category: ENT & OMF Authors: Lizhong Liang, Haiji Luo, Qifen He, Yingying You, Yunping Fan, Jun Liang Source Type: research

Cytotoxic and inflammatory effects of alendronate and zolendronate on human osteoblasts, gingival fibroblasts and osteosarcoma cells
The aim of this paper was to assess the effects of zoledronate (ZOL) andalendronate (FOS) on apoptotic behaviour and gene expression of pro- and inflammatory cytokines of three cell types (human osteoblasts, human gingival fibroblasts and human osteogenic sarcoma cell lines) during a period of 4 weeks. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - January 10, 2018 Category: ENT & OMF Authors: Yahya A çil, Mia Leena Arndt, Aydin Gülses, Henning Wieker, Hendrik Naujokat, Mustafa Ayna, Jörg Wiltfang Source Type: research

Alveolar corticotomies for accelerated orthodontics: A systematic review
It has been suggested that alveolar corticotomies may accelerate tooth movement, broaden the scope of malocclusion types that can be treated orthodontically, decrease the need for extractions, and support long-term stability. Several techniques have been proposed, although the indications, ideal design and technical characteristics, potential complications, and objective clinician and patient satisfaction remain unclear. This systematic review aimed to provide scientific support to validate alveolar corticotomies as a reliable approach to accelerated orthodontics. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - January 8, 2018 Category: ENT & OMF Authors: Ariane Paredes de Sousa Gil, Orion Luiz Haas, I. M éndez-Majón, J. Masiá-Gridilla, A. Valls-Ontañón, F. Hernández-Alfaro, R. Guijarro-Martínez Tags: Review Source Type: research

A worldwide comparison of the management of surgical treatment of advanced oral cancer
Microvascular surgery following tumor resection has become an important field of oral and maxillofacial surgery (OMFS). Following the results from management of T1/T2 floor-of-mouth and tongue squamous cell carcinoma (SCC) in German-speaking countries, Europe, and worldwide, this paper presents specific concepts for the management of resection and reconstruction of T3/T4 SCC of the maxillary and mandibular alveolar process and tongue. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - January 8, 2018 Category: ENT & OMF Authors: Katinka Kansy, Andreas Albert Mueller, Thomas M ücke, Friederike Koersgen, Klaus Dietrich Wolff, Hans-Florian Zeilhofer, Frank Hölzle, Winnie Pradel, Matthias Schneider, Andreas Kolk, Ralf Smeets, Julio Acero, Piet Haers, G.E. Ghali, Jürgen Hoffmann Source Type: research

“National Trends in Tongue Reduction Surgery for Macroglossia in Children”
1. To examine the frequency of partial glossectomy performed for the indication of macroglossia in children within the United States, assessing for differences in rates of intervention across various demographics. 2. To identify potential morbidities associated with partial glossectomy in this population and determine how such factors may influence length of stay and cost of admission following tongue reduction surgery. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - January 4, 2018 Category: ENT & OMF Authors: Jonathan C. Simmonds, Anju K. Patel, Nicholas S. Mader, Andrew R. Scott Source Type: research

Histo-morphologic characteristics of intra-osseous implants of WE43 Mg alloys with and without heat treatment in an in vivo cranial bone sheep model
WE43 Mg alloy, composed of Mg, Yttrium, Rare Earth elements, and Zirconium, has proved to be a suitable candidate for production of resorbable osteosynthesis implants in both clinical and experimental settings. In a previous study we tested biocompatibility and degradation properties of untreated (as-cast) and artificially aged (T-5) WE43 Mg-alloys as subperiosteal implants on a maxillofacial sheep model. Both the alloy compositions showed excellent biocompatibility, however, with respect to degradation rate, the as-cast form showed increased degradability compared with the T-5. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - January 4, 2018 Category: ENT & OMF Authors: Andrea Torroni, Chongchen Xiang, Lukasz Witek, Eduardo D. Rodriguez, Roberto L. Flores, Nikhil Gupta, Paulo G. Coelho Source Type: research

Correlation between pain and MRI findings in TMD patients
Magnetic resonance imaging has been established as the gold standard for assessment of the temporomandibular joint. Apart from an excellent assessment of the soft tissues it has the advantage not to expose the patient to ionizing radiation. There is a lack of literature concerning the correlation between pain intensity and radiological findings of the temporomandibular joint. Moreover there is the question of whether a progressive degeneration of the cartilaginous components is accompanied by an increasing degeneration of the osseous parts of the mandibular joint and vice versa. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - January 4, 2018 Category: ENT & OMF Authors: Matthias C. Wurm, Tessa K. Behrends, W üst Wolfgang, Marco Wiesmüller, Andre Wilkerling, Friedrich W. Neukam, Tilo Schlittenbauer Source Type: research

Effect of different doses and durations of teriparatide therapy on resolution of medication-related osteonecrosis of the jaw: A randomized, controlled preclinical study in rats
To evaluate the effects of different doses and durations of teriparatide therapy on MRONJ resolution in rats. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 30, 2017 Category: ENT & OMF Authors: Mohammad Zandi, Arash Dehghan, Najmeh Zandipoor, Payam Amini, Shideh Doulati Source Type: research

Location of the euryon in scaphocephalic vs. non-scaphocephalic controls: A novel assessment of cranial vault remodeling outcomes
We describe a novel measurement of cranial morphology in pre- and post-operative scaphocephalic patients to complement the cephalic index. This will better describe restoration of normal skull and head shape, further defining the nuances of the corrected skull. In this retrospective comparative study the location of the euryon on the skull was statistically significantly different in preoperative scaphocephalic patients versus non-scaphocephalic controls. This difference was resolved with surgical cranial vault remodeling, indicating restoration of a normal skull profile. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 29, 2017 Category: ENT & OMF Authors: Ryan Winters, Sherard A. Tatum Source Type: research

Bioabsorbable plates versus metal miniplate systems for use in endoscope-assisted open reduction and internal fixation of mandibular subcondylar fractures
To compare bioabsorbable plates with metal miniplate systems for use in endoscope-assisted open reduction and internal fixation (EAORIF) of mandibular subcondylar fractures. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 29, 2017 Category: ENT & OMF Authors: Dong-Yul Kim, Iel-Yong Sung, Yeong-Cheol Cho, Eun-ji Park, Jang-Ho Son Source Type: research

Volumetric mandibular change after angle ostectomy and outer cortex grinding
Mandibular angle ostectomy is one of the most common surgical procedures for facial contouring in Asian women. However, some patients complain about mandibular angle hypertrophy recurrence after surgery. The present study evaluated volumetric change of the mandible after angle ostectomy and outer cortex grinding. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 28, 2017 Category: ENT & OMF Authors: Jingyi Zhao, Guodong Song, Xianlei Zong, Xiaonan Yang, Le Du, Xiaoshuang Guo, Chenzhi Lai, Zuoliang Qi, Xiaolei Jin Source Type: research

The ideal ear position in Caucasian females
This study aimed to further evaluate whether there exists a universally applicable ideal ear axis, and how sociodemographic factors impact such preferences. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 26, 2017 Category: ENT & OMF Authors: P. Niclas Broer, Aung Thiha, Denis Ehrl, Sammy Sinno, Sabrina Juran, Caroline Szpalski, Reuben Ng, Milomir Ninkovic, Lukas Prantl, Paul I. Heidekrueger Source Type: research

Three-dimensional titanium miniplates for fixation of subcondylar mandibular fractures: Comparison of five designs using patient-specific finite element analysis
The purpose of the current study is to compare the performance of five designs of three-dimensional titanium miniplates (lambda, strut, delta, rhombic and trapezoid) for fixation of subcondylar mandibular fracture. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 26, 2017 Category: ENT & OMF Authors: Mhd Hassan Albogha, Yoshihide Mori, Ichiro Takahashi Source Type: research

Early cell response of osteogenic cells on differently modified implant surfaces: sequences of cell proliferation, adherence and differentiation
Osseointegration of dental implants is a crucial prerequisite for long-term survival. Therefore, surface modifications are needed to interact with the extracellular environment and to trigger osteogenic cell responses such as cell proliferation, adherence, and differentiation. The purpose of this study was to investigate different surface modifications in vitro over 2 weeks. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 26, 2017 Category: ENT & OMF Authors: Sebastian Blatt, Andreas Max Pabst, Eik Schiegnitz, Marco Hosang, Thomas Ziebart, Chirstian Walter, Bilal Al-Nawas, Marcus Oliver Klein Source Type: research

Reanimation of the paralyzed lids by cross-face nerve graft and platysma transfer
Alterations of facial muscles may critically humper patients ’ quality of life. One of the worst conditions is the reduction or abolition of eye blinking. To prevent these adverse effects, surgical rehabilitation of eyelid function is the current treatment choice. In the present paper, we present a modification of the technique devised by Nassif to recover lids from long-standing paralysis. In our modification, the upper lid is rehabilitated by a platisma graft innervated by the contralateral facial nerve branches using a cross-face sural nerve graft. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 26, 2017 Category: ENT & OMF Authors: Federico Biglioli, Matteo Zago, Fabiana Allevi, Daniela Ciprandi, Giovanni Dell ’Aversana Orabona, Valentina Pucciarelli, Dimitri Rabbiosi, Ilaria Pacifici, Filippo Tarabbia, Chiarella Sforza Source Type: research

Squamous odontogenic tumor and squamous odontogenic tumor-like proliferations in odontogenic cysts: an updated analysis of 170 cases reported in the literature
To integrate the available data published on squamous odontogenic tumors (SOT) and squamous odontogenic tumor-like proliferations in odontogenic cysts (SOT-LPOC) into a comprehensive analysis of their clinical/radiologic features. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 26, 2017 Category: ENT & OMF Authors: Bruno Ramos Chrcanovic, Ricardo Santiago Gomez Tags: Review Source Type: research

Computed exophthalmometry is an accurate and reproducible method for the measuring of eyeballs' protrusion
The aim of this study was to assess reproducibility of the repeated measurements from proposed computed exophthalmometry and to make a comparison with the Hertel exophthalmometer. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 26, 2017 Category: ENT & OMF Authors: Daria S. Afanasyeva, Marina B. Gushchina, Maxim Y. Gerasimov, Sergey A. Borzenok Source Type: research

Comparison of preseptal and retroseptal transconjunctival approaches in patients with isolated fractures of the orbital floor
Tranconjunctival approaches have become standard and are the first choices of most surgeons, associated with good esthetic results, surgically ideal overviews, and avoidance of functional disturbances caused by the incision (Schm äl et al., 2006; Ridgway et al. 2009; Novelli et al. 2011; Santosh and Giraddi, 2011). Typical complications after accessing the orbit and the infraorbital rim are eyelid retraction and symblepharon formation (Bruneau and Scolozzi, 2015; Ishida, 2016; Novelli et al., 2011). (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 23, 2017 Category: ENT & OMF Authors: Salem Barcic, Michael Blumer, Harald Essig, Paul Schumann, Daniel B. Wiedemeier, Martin R ücker, Thomas Gander Source Type: research

Melanoma-associated antigen A11 reduces erlotinib and afatinib efficacy in head and neck cancer
Melanoma-associated antigen A (MAGE-A) proteins are members of the cancer/testis antigens (CTA), and the expression of these proteins is almost exclusively limited to malignant cells, making them an attractive treatment target. MAGE-A expression is correlated with poor overall survival in several cancers, including head and neck squamous cell carcinoma (HNSCC). Among others, MAGE-A11 was found to be associated with resistance to different antineoplastic and targeted compounds, such as epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 23, 2017 Category: ENT & OMF Authors: Stefan Hartmann, Leonie Zwick, Katja Maurus, Andreas R. Fuchs, Roman C. Brands, Axel Seher, Alexander C. K übler, Urs D.A. Müller-Richter Source Type: research

Editorial Board
(Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 22, 2017 Category: ENT & OMF Source Type: research

EACMFS Awards
The Council of EACMFS wishes to ensure that all members of the Association are aware of the current awards and prizes that are available. These are designed to provide educational support and also to allow the opportunity for trainees and those who have recently achieved specialist status to visit units outside their own departments. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 22, 2017 Category: ENT & OMF Source Type: research

Announcements
Dear Colleagues, (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 22, 2017 Category: ENT & OMF Source Type: research

Comparison analysis of orbital shape and volume in unilateral fractured orbits
Facial fractures often result in changes of the orbital volume. These changes can be measured in three-dimensional (3D) computed tomography (CT) scans for preoperative planning and postoperative evaluation. The aim of this study was to analyze the orbital volume and shape before and after surgical treatment of unilateral orbital fractures using semi-automatic image segmentation and registration techniques. The orbital volume in 21 patients was assessed by a semi-automatic model-based segmentation method. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 21, 2017 Category: ENT & OMF Authors: Johanna Nilsson, Johan Nysj ö, Anders-Petter Carlsson, Andreas Thor Source Type: research

Is the routine practice of antibiotic prescription and microbial culture and antibiotic sensitivity testing justified in primary maxillofacial space infection patients? A prospective, randomized clinical study
The purpose of this prospective, randomized, comparative clinical study was to compare treatment outcome of removal of foci and incision and drainage, with or without oral antibiotic therapy, in the management of single primary maxillofacial space infection with a known focus. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 20, 2017 Category: ENT & OMF Authors: Saroj Kumari, Sujata Mohanty, Pankaj Sharma, Jitender Dabas, Sanchaita Kohli, Cathrine Diana Source Type: research

Is the routine practice of antibiotic prescription and microbial culture & antibiotic sensitivity testing justified in primary maxillofacial space infection patients? - a prospective, randomized, comparative clinical study
The purpose of this prospective, randomized, comparative clinical study was to compare treatment outcome of removal of foci and incision and drainage, with or without oral antibiotic therapy, in the management of single primary maxillofacial space infection with a known focus. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 20, 2017 Category: ENT & OMF Authors: Saroj Kumari, Sujata Mohanty, Pankaj Sharma, Jitender Dabas, Sanchaita Kohli, Cathrine Diana Source Type: research

Development of a new three-directional distractor system for the correction of maxillary transverse and sagittal deficiency
Class 3 malocclusions with maxillary deficiency, which are treated surgically and/or ordonotically, are common among adult patients. The aim of this study was to develop a three-directional bone-borne distractor that would allow the transverse expansion and sagittal advancement of the maxilla simultaneously. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 18, 2017 Category: ENT & OMF Authors: Canay Y ılmaz Asan, Nükhet Kütük, Gökmen Kurt, Alper Alkan Source Type: research

Three-dimensional analysis of cranial base morphology in patients with hemifacial microsomia
In this study, we aimed to verify whether the cranial base is involved in hemifacial microsomia (HFM). (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 16, 2017 Category: ENT & OMF Authors: Xiaojun Chen, Aung M. Zin, Li Lin, Yu Xin, Wei Chen, Wenqing Han, Yan Zhang, Gang Chai, Xianxian Yang Source Type: research

Ewing's sarcoma of the maxillofacial region in Greek children: Report of 6 cases and literature review
The rarity of Ewing's sarcoma (ES) in the maxillofacial region of children, coupled with the technical challenge of resection and associated functional and cosmetic impairment has resulted in deficient data regarding the optimal local control of the disease. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 16, 2017 Category: ENT & OMF Authors: Ioannis Iatrou, Nadia Theologie-Lygidakis, Ourania Schoinohoriti, Fotios Tzermpos, Anastassios I. Mylonas Source Type: research

“Three-dimensional Analysis of Cranial Base Morphology in Patients with Hemifacial Microsomia.”
In this study, we aimed to verify whether the cranial base is involved in hemifacial microsomia (HFM). (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 16, 2017 Category: ENT & OMF Authors: Xiaojun Chen, Aung M. Zin, Li Lin, Yu Xin, Wei Chen, Wenqing Han, Yan Zhang, Gang Chai, Xianxian Yang Source Type: research

Ewing ’s Sarcoma of the Maxillofacial Region In Greek Children: Report of 6 Cases and Literature Review
Ewing ’s sarcoma (ES) is the second most common primary bone tumor in children and adolescents after osteosarcoma, initially described by Ewing in 1921 as an undifferentiated tumor involving the diaphysis of long bones that, unlike osteosarcoma, was radiation sensitive (Thorn et al. 2016). It accounts f or approximately 3% of pediatric cancers and is most commonly diagnosed during the second decade of life, with a male to female ratio of 1.3:1 (Bernstein et al. 2006; Grevener et al. 2016). It usually affects the pelvis and long bones; extraskeletal tumors are rare in children (Osborn et al. (Source: Journal of Cranio...
Source: Journal of Cranio-Maxillofacial Surgery - December 16, 2017 Category: ENT & OMF Authors: Iatrou Ioannis, Theologie-Lygidakis Nadia, Schoinohoriti Ourania, Tzermpos Fotis, Mylonas Anastasios Source Type: research

Comparison of clinicoradiological findings between patients with recovering diplopia and those with residual diplopia after surgery for pure orbital blowout fracture
Diplopia is a common symptom of blowout fracture (BOF), and can persist after proper surgical management. We compared clinicoradiological findings between patients with recovering diplopia and those with residual diplopia after surgery for orbital BOF. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 15, 2017 Category: ENT & OMF Authors: Hye Na Jung, Sang-il Suh, Hyung-Jin Kim, Inseon Ryoo Source Type: research

Comparison with clinicoradiologic findings between patients with recovering and those with residual diplopia after surgery of pure orbital blowout fracture
Diplopia is a common symptom of blowout fracture (BOF), and can persist after proper surgical management. We compared clinicoradiological findings between patients with recovering diplopia and those with residual diplopia after surgery for orbital BOF. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 15, 2017 Category: ENT & OMF Authors: Hye Na Jung, Sang-il Suh, Hyung-Jin Kim, Inseon Ryoo Source Type: research

Rearthroscopy of The Temporomandibular Joint: a Retrospective study of 600 Arthroscopies
Arthroscopic surgery is an effective treatment for patients with temporomandibular disorders, releasing symptoms and restoring the mandibular function. In patients with poor arthroscopic outcomes, several options of treatment can be considered such as conservative nonsurgical therapy, open surgery, or a second arthroscopy. The purpose of this study was to evaluate our results after 619 arthroscopies. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 15, 2017 Category: ENT & OMF Authors: R. Martin-Granizo, D.C. Correa, E. Varela Source Type: research

Comparative Study of Biomechanical Stability Of Resorbable And Titanium Fixation Systems After Sagittal Split Ramus Osteotomy With A Novel Designed In-Vitro Testing Unit
Sagittal split ramus osteotomy (SSRO) is one of the most popular surgical procedures for correction of mandibular deformities. Several clinical and biomechanical studies exist in the literature which, comparing the stability of different osteosynthesis materials and techniques, were performed using two or three-point biomechanical test models. The aim of this study was to compare the stability of biodegradable and titanium materials for SSRO on one-piece polyurethane mandible samples which were fixed in a novel designed 6-point testing unit. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 13, 2017 Category: ENT & OMF Authors: Murat Ulu, Emrah Soylu, Seyfi Kelebek, Serkan Dikici, Hakan Oflaz Source Type: research

Stiffness and strength of cranioplastic implant systems in comparison to cranial bone
The aim of this study was to evaluate skull replacement options after decompressive craniectomy by systematically investigating which combination of geometrical properties and material selection would result in a mechanical response comparable in stiffness to that of native skull bone and a strength as high or higher than the same. Materials and methods: The study was conducted using a Finite Element Model of the top part of a human skull. Native skull bone, autografts and commercial implants made of PEEK, solid titanium, two titanium meshes and a titanium-ceramic composite were modeled under a set load to evaluate deforma...
Source: Journal of Cranio-Maxillofacial Surgery - December 13, 2017 Category: ENT & OMF Authors: Johan Persson, Benedikt Helgason, H åkan Engqvist, Stephen J. Ferguson, Cecilia Persson Source Type: research

Hemoglobin, C-reactive protein and ferritin in patients with oral carcinoma and their clinical significance - a prospective clinical study
For oral squamous cell carcinoma (OSCC), biomarkers are much in need to predict prognosis and to overcome possible resistance mechanisms to adjuvant therapies. The aim of this study was to evaluate serum level of hemoglobin, C-reactive protein (CRP) and ferritin as possible liquid biopsy to predict survival, metastasis and tumor relapse of OSCC. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 13, 2017 Category: ENT & OMF Authors: Sebastian Blatt, Holger Sch ön, Keyvan Sagheb, Peer W. Kämmerer, Bilal Al-Nawas, Eik Schiegnitz Source Type: research

Commentary: “Maxillofacial growth and speech outcome after one-stage or two-stage palatoplasty in unilateral cleft lip and palate. A systematic review”
We would like to congratulate Reddy et al with their recent publication “Maxillofacial growth and speech outcome after one-stage or two-stage palatoplasty in unilateral cleft lip and palate. A systematic review” published in J Craniomaxillofac Smarius and Breugem, 2015 45(6):995-1003(1). Although this review is a valuable adjunct to the medical literature, we do hav e some comments about this manuscript. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 13, 2017 Category: ENT & OMF Authors: Bram J.A. Smarius, Corstiaan C. Breugem Tags: Letter to the Editor Source Type: research

Predictors of speech outcomes in children with Pierre Robin sequence
Pierre Robin sequence (PRS) has worse speech outcomes than isolated cleft palate. We aimed to search for possible associations of phonological outcomes with PRS status (isolated vs syndromic), clinical severity, soft palate muscles deficiency, or surgical procedure. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 13, 2017 Category: ENT & OMF Authors: Anne Morice, Francis Renault, V éronique Soupre, Cécile Chapuis, Chantal Trichet Zbinden, Natacha Kadlub, Amerigo Giudice, Marie-Paule Vazquez, Arnaud Picard Source Type: research

A comprehensive management protocol to treat cleft maxillary hypoplasia
Maxillary hypoplasia is the most commonly encountered secondary deformity as a result of cleft lip and palate with a reported incidence of about 15-50%(Liao YF, Mars M 2005).The reasons understood for this hypoplasia are twofold, firstly that the cleft maxilla ’s intrinsic potential of growth is less due to the developmental deficiency. Secondly, the iatrogenic factor created due to the surgical repair of cleft lip and palate causes scarring which inhibits the normal growth of the maxilla (Ross 1987).Due to the class III malocclusion that develops in th ese patients, treatment in some form or other is required to res...
Source: Journal of Cranio-Maxillofacial Surgery - December 13, 2017 Category: ENT & OMF Authors: Sunil Richardson, Shreya Krishna, Rakshit V. Khandeparker Source Type: research

Melanotic neuroectodermal tumor of infancy (MNTI) of the head and neck: A French multicenter study
Melanotic neuroectodermal tumor of infancy (MNTI) of the head and neck is a rare entity with uncertain clinical behavior. Radical surgical resection is the current recommended treatment, however this can cause severe aesthetic and functional sequelae. The aim of this study was to clinically characterize MNTIs and to stratify risk factors that may influence locoregional recurrence. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 12, 2017 Category: ENT & OMF Authors: Audrey Moreau, Louise Galmiche, Veronique Minard-Colin, Martin Rachwalski, Kahina Belhous, Daniel Orbach, Aline Joly, Arnaud Picard, Natacha Kadlub Source Type: research

Outcome and complications after treatment of facial fractures at different times in polytrauma patients
Finding the correct point of time for operative treatment of facial fractures in multiply injured people remains one of the most important challenges in modern emergency medicine. Findings relating to pathophysiological mechanisms after severe trauma argue against the early operative treatment of non-life-threatening injuries. Our retrospective analysis investigated the effects on complications and outcome of different time points for operative treatment of maxillofacial fractures in multiply injured patients. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 8, 2017 Category: ENT & OMF Authors: Rene Rothweiler, Joerg Bayer, Joern Zwingmann, Norbert P. Suedkamp, Johannes Kalbhenn, Rainer Schmelzeisen, Ralf Gutwald Source Type: research

Orbital volume and shape in Treacher Collins syndrome
This study investigates orbital phenotypes in TCS using cephalometry and orbital shape analysis.Eighteen TCS and 52 control patients were included in this study, using the Dr Warehouse database. Orbital cephalometry was based on 20 landmarks, 10 planes, 16 angles, and 22 distances. Orbits were segmented. Registration-based, age-specific mean models were generated using semi-automatic segmentation, and aligned and compared using color-coded distance maps – maximum absolute distance (MAD), Hausdorff distance (HD), and Dice similarly coefficient (DSC). (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 8, 2017 Category: ENT & OMF Authors: Julie Levasseur, Johan Nysj ö, Ronak Sandy, Jonathan A. Britto, Nicolas Garcelon, Samer Haber, Arnaud Picard, Pierre Corre, Guillaume A. Odri, Roman H. Khonsari Source Type: research

Accuracy of computer-assisted orthognathic surgery
The purpose of this study was to retrospectively evaluate the difference between the planned and the actual movements of the jaws, using three-dimensional (3D) software for PC-assisted orthognathic surgery, to establish the accuracy of the procedure. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 2, 2017 Category: ENT & OMF Authors: Giacomo De Riu, Paola Ilaria Virdis, Silvio Mario Meloni, Aurea Lumbau, Luigi Angelo Vaira Source Type: research

Editorial Board
(Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 1, 2017 Category: ENT & OMF Source Type: research

EACMFS Awards
The Council of EACMFS wishes to ensure that all members of the Association are aware of the current awards and prizes that are available. These are designed to provide educational support and also to allow the opportunity for trainees and those who have recently achieved specialist status to visit units outside their own departments. (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 1, 2017 Category: ENT & OMF Source Type: research

Announcements
Dear Colleagues, (Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 1, 2017 Category: ENT & OMF Source Type: research

Keyword index: Volume 45
(Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 1, 2017 Category: ENT & OMF Source Type: research

Contents: Volume 45
(Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 1, 2017 Category: ENT & OMF Source Type: research

Author Index: Volume 45
(Source: Journal of Cranio-Maxillofacial Surgery)
Source: Journal of Cranio-Maxillofacial Surgery - December 1, 2017 Category: ENT & OMF Source Type: research