Cancer Survivors Who Had Chest Radiation At Increased Mortality Risk Following Heart Surgery
Cancer survivors who had chest radiation are nearly twice as likely to die in the years after having major heart surgery as similar patients who didn't have radiation, according to research in the American Heart Association journal Circulation. Chest radiation to kill or shrink breast cancer, Hodgkin's lymphoma and other cancers increases survivors' risk for major heart disease years - even decades - after radiation therapy... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 10, 2013 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

PET Projects Treatment Response in Adult Hodgkin's Disease
ATLANTA (IMNG) - Patients with a positron-emission tomography-confirmed response to chemotherapy for Hodgkin's lymphoma can be safely spared from radiotherapy without fear of compromising disease control,... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 1, 2013 Category: Cancer & Oncology Source Type: news

Cancer death rates are a third higher in men
The fact that men are more likely than women to both develop and die from cancer has been covered by most of the media today. The news is based on a report highlighting the excess cancer burden in men (both in terms of cases and deaths), and was produced by Cancer Research UK, the Men’s Health Forum and the National Cancer Intelligence Network. The results of the report were widely and accurately reported in the media. The report found that men are at significantly greater risk of both developing and dying from cancer, and the difference in risk increased further when breast and sex-specific cancers, for example cervi...
Source: NHS News Feed - January 29, 2013 Category: Consumer Health News Tags: Cancer QA articles Source Type: news

Five-Minute' Blood Cancer Injection Cuts Treatment Time By Two Hours
A new injection for blood cancer patients trialled at Southampton's teaching hospitals can deliver a two-hour dose of drugs in around five minutes. Patients diagnosed with follicular non-Hodgkin lymphoma (NHL), a disease that attacks one specific type of infection-fighting cell, previously had rituximab administered via an intravenous drip... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 24, 2013 Category: Consumer Health News Tags: Lymphoma / Leukemia / Myeloma Source Type: news

PCR-Based Analysis of Rearranged Immunoglobulin or T-Cell Receptor Genes by GeneScan Analysis or Heteroduplex Analysis for Clonality Assessment in Lymphoma Diagnostics
The assessment of the presence of clonal lymphoproliferations via polymerase chain reaction (PCR)-based analysis of rearranged immunoglobulin (Ig) or T-cell receptor (TCR) genes is a valuable technique in the diagnosis of suspect lymphoproliferative disorders. Furthermore this technique is more and more used to evaluate dissemination of non-Hodgkin lymphoma and/or the presence of (minimal) residual disease. In this chapter we describe an integrated approach to assess clonality via analysis of Ig heavy chain (IGH), Ig kappa (IGK), TCR beta (TCRB), and TCR gamma (TCRG) gene rearrangements. The described PCR protocol is based...
Source: Springer protocols feed by Cancer Research - January 11, 2013 Category: Cancer & Oncology Source Type: news

Flow Cytometry for Non-Hodgkin and Classical Hodgkin Lymphoma
Multiparametric flow cytometry is a powerful diagnostic tool that permits rapid assessment of cellular antigen expression to quickly provide immunophenotypic information suitable for disease classification. This chapter describes a general approach for the identification of abnormal lymphoid populations by flow cytometry, including B, T, and Hodgkin lymphoma cells suitable for the clinical and research environment. Knowledge of the common patterns of antigen expression of normal lymphoid cells is critical to permit identification of abnormal populations at disease presentation and for minimal residual disease assessment. W...
Source: Springer protocols feed by Cancer Research - January 11, 2013 Category: Cancer & Oncology Source Type: news

MRD Detection in B-Cell Non-Hodgkin Lymphomas Using Ig Gene Rearrangements and Chromosomal Translocations as Targets for Real-Time Quantitative PCR
Minimal residual disease (MRD) diagnostics is of high clinical relevance in patients with indolent B-cell Non-Hodgkin lymphomas (B-NHL) and serves as a surrogate parameter to evaluate treatment effectiveness and long-term prognosis. MRD diagnostics performed by real-time quantitative PCR (RQ-PCR) is the gold-standard and currently the most sensitive and the most broadly applied method in follicular lymphoma (FL) and mantle cell lymphoma (MCL). RQ-PCR analysis of the junctional regions of the rearranged immunoglobulin heavy-chain gene (IgH) serves as the most broadly applicable MRD target in B-NHL (∼80%). Chromosomal tr...
Source: Springer protocols feed by Cancer Research - January 11, 2013 Category: Cancer & Oncology Source Type: news

Epigenomic abnormalities predict patient survival in non-Hodgkins lymphoma
"Not only do we see more abnormal methylation in non-Hodgkin lymphoma patients than in healthy B-cell populations, but there are three distinct subtypes of the disease in the clinic, each more aggressive than the next. These three clinical trajectories of non-Hodgkins lymphoma were distinctly marked by their levels of abnormal methylation," says a CU Cancer Center investigator. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 11, 2013 Category: Science Source Type: news

Epigenomic abnormalities predict patient survival in non-Hodgkins lymphoma
(University of Colorado Denver) "Not only do we see more abnormal methylation in non-Hodgkin lymphoma patients than in healthy B-cell populations, but there are three distinct subtypes of the disease in the clinic, each more aggressive than the next. These three clinical trajectories of non-Hodgkins lymphoma were distinctly marked by their levels of abnormal methylation," says a CU Cancer Center investigator. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 10, 2013 Category: Cancer & Oncology Source Type: news

Two medical pioneers aim to trial a cancer-killing virus. I aim to help out | Alexander Masters
A pair of researchers in Sweden may have a revolutionary cancer treatment on their hands. But a separate revolution will be needed to get it to marketJust north of Stockholm, among the creaking Swedish ice-forests, three revolutions for 2013 are taking place.Revolution One: Two researchers at the University of Uppsala have engineered a virus that will attack cancer. Cheap, precise, with only mild, flu-like side-effects, this plucky little microbe sounds too good to be true. Yet in peer-reviewed articles in top journals, Professor Magnus Essand and Dr Justyna Leja have repeatedly showed that Ad5[CgA-E1A-miR122]PTD views hea...
Source: Guardian Unlimited Science - January 4, 2013 Category: Science Authors: Alexander Masters Tags: Comment The Guardian Crowdsourcing Health Medical research Society Technology Kickstarter Features Cancer Internet Science Comment is free Source Type: news

ADAO Lights a Candle for Workers' Memorial Day
On April 28, the Asbestos Disease and Awareness Organization (ADAO) will recognize Workers' Memorial Day through their Light a Candle program. The program encourages people to light a candle or do so through their website to honor loved ones who are fighting or have lost their fight against asbestos-related diseases. As of April 26 2011, over 11 million candles have been lit in a total of 243 countries. Each year, approximately 125 million workers are regularly exposed to asbestos. Asbestos has been directly linked to the development of malignant mesothelioma, an uncommon and aggressive cancer that attacks the lining of th...
Source: Asbestos and Mesothelioma News - April 26, 2011 Category: Environmental Health Authors: Michael Sedacca Tags: Asbestos Exposure & Bans Source Type: news

Van Andel Institute conducting cancer research in Asia
The Van Andel Research Institute will soon be conducting cancer research in Southeast Asia. It’s being called a ground breaking agreement. The $1.2 million, 3 year deal is funded by the National Cancer Center in Singapore. Scientists would study types of cancer that seem to be more prevalent among certain ethnic groups. The study will compare cancer in Caucasian patients verses cancer in Asian patients. For example, prostate cancer is more prevalent among white people. Liver cancer seems be more prevalent among Asians. WZZM 13 News got a glimpse inside the Van Andel Research Institute, where doctors say they are maki...
Source: Kidney Cancer Association - November 1, 2007 Category: Urology & Nephrology Source Type: news

Van Andel Institute conducting cancer research in Asia
The Van Andel Research Institute will soon be conducting cancer research in Southeast Asia. It’s being called a ground breaking agreement. The $1.2 million, 3 year deal is funded by the National Cancer Center in Singapore. Scientists would study types of cancer that seem to be more prevalent among certain ethnic groups. The study will compare cancer in Caucasian patients verses cancer in Asian patients. For example, prostate cancer is more prevalent among white people. Liver cancer seems be more prevalent among Asians. WZZM 13 News got a glimpse inside the Van Andel Research Institute, where doctors say they ar...
Source: Kidney Cancer Association - November 1, 2007 Category: Urology & Nephrology Source Type: news

Van Andel Institute conducting cancer research in Asia
The Van Andel Research Institute will soon be conducting cancer research in Southeast Asia. It’s being called a ground breaking agreement. The $1.2 million, 3 year deal is funded by the National Cancer Center in Singapore. Scientists would study types of cancer that seem to be more prevalent among certain ethnic groups. The study will compare cancer in Caucasian patients verses cancer in Asian patients. For example, prostate cancer is more prevalent among white people. Liver cancer seems be more prevalent among Asians. WZZM 13 News got a glimpse inside the Van Andel Research Institute, where doctors say they are maki...
Source: Kidney Cancer Association - November 1, 2007 Category: Urology & Nephrology Source Type: news