NCI Trials Overhaul Eyes Community-Based Biomarker Studies
Nearly 3 years after tasking themselves with overhauling the nation's publicly funded cancer clinical trials system, which had been criticized as sluggish and unwieldy, researchers working for and with... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - March 1, 2013 Category: Cancer & Oncology Source Type: news

Colorectal Cancer Subtype Associated With Obesity, Inactivity
A specific molecular subtype of colorectal cancer is more likely in people with greater obesity and physical inactivity, analyses of prospective data on 861 cancer patients found.For every 5-kg/m² increase... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - March 1, 2013 Category: Cancer & Oncology Source Type: news

Third Drug Approved for Metastatic, Treatment-Resistant GIST
Regorafenib, a multikinase inhibitor, has been approved as a treatment for locally advanced, unresectable, or metastatic gastrointestinal stromal tumor in people who have been treated with imatinib and... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - March 1, 2013 Category: Cancer & Oncology Source Type: news

Trends in Post-Treatment Leukemia
The risks of chemotherapy-related acute myeloid leukemia have changed significantly over the last 30 years, increasing in people treated for non-Hodgkin's lymphoma and decreasing in people treated for... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 28, 2013 Category: Cancer & Oncology Source Type: news

Metastatic Breast Cancer Incidence is Rising Among Young Women
The incidence of breast cancer presenting with distant involvement has risen significantly over the past 30 years among young women, and this trend shows no signs of abating, according to a report in the... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 28, 2013 Category: Cancer & Oncology Source Type: news

Selective Resection Feasible for Esophageal Cancer
SAN FRANCISCO (IMNG) - Five-year survival rates for 41 patients with locoregionally advanced esophageal cancer who underwent induction chemotherapy and definitive chemoradiotherapy were 53% for patients... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 27, 2013 Category: Cancer & Oncology Source Type: news

Abiraterone Reduced Morbidity in MCRPC Patients
Treatment with both drugs also delayed times to opiate use and chemotherapy, was associated with improved quality of life measures, and remained safe and well tolerated, said Dr. Dana E. Rathkopf, the... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 27, 2013 Category: Cancer & Oncology Source Type: news

FOLFOXIRI Bests FOLFIRI When Bevacizumab is Added in Colorectal Cancer
SAN FRANCISCO (IMNG) - Adding bevacizumab to the FOLFOXIRI regimen significantly delayed the median time to progression of metastatic colorectal cancer to 12.2 months, compared with 9.7 months when bevacizumab... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 27, 2013 Category: Cancer & Oncology Source Type: news

Kadcyla Wins US FDA Approval for Late-Stage Breast Cancer
Ado-trastuzumab emtansine, a HER-2 targeted antibody-drug conjugate, has been approved by the U.S. Food and Drug Administration for treatment of women with HER2-positive, late-stage metastatic breast cancer,... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 26, 2013 Category: Cancer & Oncology Source Type: news

Treatment-Related AML Rises in Non-Hodgkin's Lymphoma
The risks of chemotherapy-related acute myeloid leukemia have changed significantly over the last 30 years, increasing in people treated for non-Hodgkin's lymphoma and decreasing in people treated for... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 26, 2013 Category: Cancer & Oncology Source Type: news

Lung Cancer CT Screens Could Save 12,000 Lives
Roughly 12,250 deaths could be delayed or prevented each year if a national lung cancer computed tomography screening program were implemented among heavy smokers in the United States.That represents about... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 26, 2013 Category: Cancer & Oncology Source Type: news

Clinical Staging of Early Esophageal Cancer Unreliable
LOS ANGELES (IMNG) - Clinical staging of T2N0 esophageal cancer remains unreliable, despite advances in staging techniques, a study has shown.The addition of endoscopic ultrasound and PET/CT has improved... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 23, 2013 Category: Cancer & Oncology Source Type: news

New Lung Cancer Data May Offer Reprieve for Peregrine's Bavituximab
Peregrine Pharmaceuticals Inc. is gearing up for a Phase III pivotal study of its bavituximab in second-line non-small cell lung cancer of at the end of 2013, after concluding the drug showed an overall... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 23, 2013 Category: Cancer & Oncology Source Type: news

Cancer Incidence and Mortality Hit Blacks Hardest
The incidence and mortality of invasive cancers were higher for blacks than for all other ethnicities in the United States in 2009, according to data from the U.S. Centers for Disease Control and Prevention.The... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 23, 2013 Category: Cancer & Oncology Source Type: news

Survival Higher With Surveillance of Small Kidney Tumors
Older patients with small kidney tumors are up to 70% less likely to die from any cause when managed by watchful waiting rather than by surgery, based on findings from a large retrospective study.Surveillance... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 19, 2013 Category: Cancer & Oncology Source Type: news

Age, Race Impact Prostate Cancer Risk
Prostate cancers detected during screening are much more likely to be high risk when they affect black men and men aged 75 years or older.Men over age 74 years were nine times more likely to have high-risk... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 16, 2013 Category: Cancer & Oncology Source Type: news

Survival Shorter in Young Gastric Cancer Patients
SAN FRANCISCO (IMNG) - Patients with gastric adenocarcinoma who were diagnosed before age 40 years died significantly sooner than did older patients, based on the results of a single-center, retrospective... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 16, 2013 Category: Cancer & Oncology Source Type: news

Race Effects On Gastric Cancer Prognosis Have Evolved
SAN FRANCISCO (IMNG) - Race is a significant predictor of the odds of surviving gastric cancer at the time of diagnosis: Its impact lessens the longer the patient survives, an analysis of data on 24,657... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 16, 2013 Category: Cancer & Oncology Source Type: news

Capecitabine Chemoradiotherapy Effective in Local Pancreatic Cancer
SAN FRANCISCO (IMNG) - Following induction chemotherapy with radiotherapy plus capecitabine seemed to be equally effective and less toxic compared with following with radiotherapy plus gemcitabine in a... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 16, 2013 Category: Cancer & Oncology Source Type: news

No Early Cancer Risk With Donor Lungs From Heavy Smokers
LOS ANGELES (IMNG) - Use of lungs from donors who smoked heavily does not worsen lung transplantation outcomes including risk for lung cancer death, at least in the medium term.At a median follow-up of... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 15, 2013 Category: Cancer & Oncology Source Type: news

Assay May Target Early Lung Cancers for Adjuvant Therapy
LOS ANGELES (IMNG) - A novel genetic assay helps identify patients with early, aggressive lung cancer who might benefit from adjuvant therapy.The assay, marketed as Pervino Lung RS by Life Technologies,... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 15, 2013 Category: Cancer & Oncology Source Type: news

Gene Profiling Predicted Responses to Colorectal, Pancreatic Cancer Treatment
SAN FRANCISCO (IMNG) - Gene expression profiling of patients with colorectal cancer and pharmacogenomic modeling of patients with pancreatic cancer could help identify which patients will respond to particular... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 14, 2013 Category: Cancer & Oncology Source Type: news

Breast-Conserving Therapy Improved Survival over Mastectomy
Women who underwent lumpectomy for stage I or II breast cancer were 28% less likely to die from any cause and up to 16% less likely to die from breast cancer, compared with women who underwent mastectomy,... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 14, 2013 Category: Cancer & Oncology Source Type: news

Diversity of Triple-Negative Breast Cancer Complicates Treatment
Treatment of triple-negative breast cancer, so named because it lacks estrogen receptors, progesterone receptors, and HER2 overexpression, is one of the most challenging areas of breast oncology. Not only... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 14, 2013 Category: Cancer & Oncology Source Type: news

FDA Approves Pomalidomide for Advanced Multiple Myeloma
Pomalidomide has been approved for the treatment of patients with multiple myeloma whose disease has progressed after treatment with at least two prior therapies, including lenalidomide and bortezomib,... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 12, 2013 Category: Cancer & Oncology Source Type: news

Bevacizumab Plus Chemo Extends Survival in Metastatic Cervical Cancer
Adding bevacizumab to chemotherapy extended survival by about 4 months beyond the survival achieved with chemotherapy alone in chemotherapy-naïve patients with persistent, recurrent, or metastatic cervical... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 12, 2013 Category: Cancer & Oncology Source Type: news

Screen Asymptomatic Siblings of CRC Patients
Asymptomatic siblings of Chinese colorectal cancer patients are at threefold higher risk for advanced colorectal neoplasms and at twofold higher risk for any colorectal adenoma, compared with siblings... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 12, 2013 Category: Cancer & Oncology Source Type: news

New Adjuvant to Surgery Improved Pancreatic Cancer Survival
SAN FRANCISCO (IMNG) - Japanese patients who underwent surgery for pancreatic cancer were 44% less likely to die within 2 years if they were treated postoperatively with the chemotherapy drug S-1, compared... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 12, 2013 Category: Cancer & Oncology Source Type: news

Folic Acid Supplements Have no Effect on Cancer Rates
Taking folic acid supplements neither increases nor decreases the incidence of cancer during the treatment period, according to a meta-analysis of 13 large randomized controlled trials that examined this... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 11, 2013 Category: Cancer & Oncology Source Type: news

Cancer Survival Still Lower for African Americans
The 5-year cancer survival rate for African Americans has risen 54% since the 1970s, but continues to be lower than that of whites, according to a report from the American Cancer Society.Data from the... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 9, 2013 Category: Cancer & Oncology Source Type: news

Job Stress Not Linked With Cancer Risk
Job stress was not directly associated with the risks of lung, breast, colorectal, or prostate cancer in a large retrospective study."Work-related psychosocial stress is unlikely to be an important risk... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 9, 2013 Category: Cancer & Oncology Source Type: news

Some HER2-Negative Cancers May Benefit from Anti-HER2 Therapy
SAN ANTONIO (IMNG) - Some breast cancers categorized as HER2 negative by conventional testing harbor mutations that may still render them amenable to therapy targeting this receptor, researchers reported... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 7, 2013 Category: Cancer & Oncology Source Type: news

Statins May Reduce Mortality in Hepatocellular Cancer
SAN FRANCISCO (IMNG) - The use of statins may reduce the risk of death in patients with hepatocellular cancer by 30%, a retrospective study of 639 patients suggests.Median overall survival from 2000 until... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 7, 2013 Category: Cancer & Oncology Source Type: news

Combination Therapy Better for Elderly With Colorectal Cancer
SAN FRANCISCO (IMNG) - Adding bevacizumab to capecitabine for first-line therapy for elderly patients with metastatic colorectal cancer significantly delayed disease progression and improved treatment... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 7, 2013 Category: Cancer & Oncology Source Type: news

Add-On Nab-Paclitaxel Extends Survival in Metastatic Pancreatic Cancer
SAN FRANCISCO (IMNG) - Median overall survival in 861 patients with metastatic pancreatic cancer increased from 6.7 months in those randomized to gemcitabine therapy to 8.5 months in patients receiving... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 7, 2013 Category: Cancer & Oncology Source Type: news

Second-Line Ramucirumab for Gastric/GEJ Adenocarcinoma Extends Survival
SAN FRANCISCO (IMNG) - A phase III clinical trial of an experimental monoclonal antibody for patients failing first-line treatment of metastatic gastric or gastroesophageal junction adenocarcinoma increased... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 5, 2013 Category: Cancer & Oncology Source Type: news

Adding Cetuximab Harmful in Esophageal Cancer Treatment
SAN FRANCISCO (IMNG) - A phase II/III clinical trial of adding cetuximab to chemoradiotherapy for localized esophageal cancer was stopped early when interim results showed greater toxicity, less completion... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 5, 2013 Category: Cancer & Oncology Source Type: news

New Tool Predicts Late Recurrence in Breast Cancer
SAN ANTONIO (IMNG) - A novel multigene signature known as the breast cancer index markedly outperformed the widely used Oncotype DX Recurrence Score and IHC4 tools in predicting late recurrences of estrogen... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 1, 2013 Category: Cancer & Oncology Source Type: news

Once-Daily Beta-Agonist for COPD Earns FDA Panel Support
SILVER SPRING, MD. (IMNG) - Olodaterol, an inhaled long-acting beta2-adrenergic agonist, is an effective bronchodilator and should be approved for the treatment of chronic obstructive pulmonary disease,... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 1, 2013 Category: Cancer & Oncology Source Type: news

Poll: Public Doesn't See Cancer as a Death Sentence
People are optimistic about their chances of surviving cancer, according to a poll conducted in the United States and five other wealthy nations.Among respondents in all six countries, 48% said they did... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 1, 2013 Category: Cancer & Oncology Source Type: news

Prostatectomy vs Radiotherapy: 15-Year Functional Outcomes Are the Same
Fifteen years after treatment for localized prostate cancer, men who underwent radical prostatectomy reported no differences in urinary, bowel, or sexual function compared with men who underwent external-beam... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 1, 2013 Category: Cancer & Oncology Source Type: news

PET Projects Treatment Response in Adult Hodgkin's Disease
ATLANTA (IMNG) - Patients with a positron-emission tomography-confirmed response to chemotherapy for Hodgkin's lymphoma can be safely spared from radiotherapy without fear of compromising disease control,... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - February 1, 2013 Category: Cancer & Oncology Source Type: news

Second-Line Agent for Gastroesophageal Adenocarcinoma Extends Survival
SAN FRANCISCO (IMNG) - A phase III clinical trial of an experimental monoclonal antibody for patients failing first-line treatment of metastatic gastric or gastroesophageal junction adenocarcinoma increased... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - January 31, 2013 Category: Cancer & Oncology Source Type: news

Lilly's Ramucirumab Makes an Impact in Tough-To-Treat Gastric Cancer, but Will It be Enough?
SAN FRANCISCO---Eli Lilly & Co.’s VEGF inhibitor ramucirumab made an impression when it showed single agent activity in second-line gastric cancer in the REGARD study and became one of the few non-chemotherapy... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - January 30, 2013 Category: Cancer & Oncology Source Type: news

Celgene's Abraxane Scores a Win Against Tough Pancreatic Cancer
Celgene Corp.'s nanoparticle formulation of paclitaxel, Abraxane, when added to standard of care gemcitabine, extended the life of advanced pancreatic cancer patients by 59% at one year and more than doubled... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - January 30, 2013 Category: Cancer & Oncology Source Type: news

Transplants Don't Boost Overall Survival in High-Risk DLBCL
ATLANTA (IMNG) - In young patients with high-risk diffuse large B-cell lymphoma, autologous stem cell transplantation can push the rate of progression-free survival beyond that achievable with rituximab... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - January 29, 2013 Category: Cancer & Oncology Source Type: news

Minimally Invasive Breast Biopsy Lags in Texas
PALM BEACH, FLA. (IMNG) - More than a fifth of women in Texas with image-detected breast abnormalities failed to undergo minimally invasive breast biopsy as recently as 2008, according to a review of statewide... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - January 29, 2013 Category: Cancer & Oncology Source Type: news

US Approves Imatinib for Children With Ph+ Acute Lymphoblastic Leukemia
Imatinib has been approved to treat children newly diagnosed with Philadelphia chromosome-positive acute lymphoblastic leukemia, the U.S. Food and Drug Administration announced Jan. 25.Imatinib, a tyrosine... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - January 29, 2013 Category: Cancer & Oncology Source Type: news

Lenalidomide Branches Out to Lymphoma Therapy
ATLANTA (IMNG) - Lenalidomide, already an important agent in the treatment of multiple myeloma, is also flexing its muscles against non-Hodgkin's lymphomas, reported researchers in two clinical trials... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - January 29, 2013 Category: Cancer & Oncology Source Type: news

FDA Approves Bevacizumab for Second-Line Combinations
Bevacizumab is now approved by the Food and Drug Administration for use in combination with fluoropyrimidine-irinotecan-based or fluoropyrimidine-oxaliplatin-based chemotherapy for metastatic colorectal... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - January 29, 2013 Category: Cancer & Oncology Source Type: news