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Anemia in HIV Patients Attending Highly Active Antiretroviral Therapy Clinic at Hoima Regional Referral Hospital: Prevalence, Morphological Classification, and Associated Factors
(Source: Therapeutics and Clinical Risk Management)
Source: Therapeutics and Clinical Risk Management - October 12, 2023 Category: Drugs & Pharmacology Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Bifactor SEM and MIRT Structure of a 12-Item Human Immunodeficiency Virus Stigma Scale in Peruvian Adults
CONCLUSION: It is concluded that the 12-item HIV Stigma Scale meets the psychometric properties of internal structure and unifactorial reliability.PMID:37750178 | PMC:PMC10521262 | DOI:10.1177/21501319231197589 (Source: Primary Care)
Source: Primary Care - September 26, 2023 Category: Primary Care Authors: Cristian Ramos-Vera Miguel Basauri-Delgado Misael Diaz Pe ña Jose Tinoco Alberto Karen Perez Arroyo Betsabel Herrera Mamani Andy S ánchez-Villena Jacksaint Saintila Source Type: research

Do we all need to learn aortic valve repair the HAART way?
We read with great interest the recent article by Lancaster and colleagues1 describing hemispherical aortic annuloplasty reconstructive technology (HAART) in adolescents, which requires implantation of a rigid ring inside the aorta (Figure  1, A). A few immediate questions come to mind. Is implantation of an internal ring necessary if efficient and durable stabilization could be achieved with other annuloplasty techniques? Would the expected endothelization of the ring induce fibrosis in the high-shear-stress subaortic area? Would th is, in turn, create an iatrogenic subaortic membrane and induce the spread of the fibrosi...
Source: The Journal of Thoracic and Cardiovascular Surgery - September 19, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Igor E. Konstantinov, Alexey Zubritskiy Tags: Letter to the Editor Source Type: research

Impact factors of Blastocystis hominis infection in persons living with human immunodeficiency virus: a large-scale, multi-center observational study from China
ConclusionsThe study revealed that VL was a better predictor of Bh infection than CD4+ T cell counts. It is crucial to consider the simultaneous surveillance of HIV VL and CD4+ T cell counts in PLWH in the regions with high level of socioeconomic development. The integrated approach can offer more comprehensive and accurate understanding in the aspects of Bh infection and other opportunistic infections, the efficacy of therapeutic drugs, and the assessment of preventive and control strategies.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - September 11, 2023 Category: Infectious Diseases Source Type: research

GSE235229 A truncated HIV Tat demonstrates potent and specific latency reversal activity
Contributors : Filmon Eyassu ; Ellen Van Gulck ; Marion Pardons ; Erik Nijs ; Nick verheyen ; Koen Dockx ; Christel Van den Eynde ; Jerel Vega ; Eric Florence ; Brigitte Autran ; Nancy Archin ; David Margolis ; Kristine Katlama ; Chiraz Hamimi ; Ilse Van den Wyngaert ; Filmon Eyassu ; Linos Van de Kerckhove ; Daniel BodenSeries Type : Expression profiling by arrayOrganism : Homo sapiensThe barrier to HIV-1 functional cure is caused by a small pool of latently infected resting CD4 T-cells that persist under antiretroviral therapy. Notably this latent reservoir of infected cells will produce replication-com...
Source: GEO: Gene Expression Omnibus - September 5, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research

Tenofovir disoproxil fumarate mediates neuronal injury by inducing neurotoxicity
ConclusionOur findings indicated that TDF may induce neuronal cell apoptosis through increasing the intracellular ROS and the expression level of caspase-3, which may be related to the increasing prevalence of HAND. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - August 22, 2023 Category: Microbiology Source Type: research

The use of the brief symptom inventory among youth living with HIV: a scoping review
AIDS Rev. 2023;25(2):88-95. doi: 10.24875/AIDSRev.22000016.ABSTRACTThe brief symptom inventory (BSI), a 53-item measure that assesses psychological distress, is a popular tool for measuring mental health symptoms among youth living with HIV (YLH) in the United States (US); however, it has been used inconsistently with this population. This scoping review summarizes discrepancies in the use of the BSI to identify opportunities to improve systematism and make recommendations for clinicians and researchers, and highlights correlates of psychological distress among YLH as measured by the BSI. Databases searched included PsycIN...
Source: AIDS Reviews - August 16, 2023 Category: Infectious Diseases Authors: Natasha Richmond Alyssa Steinbaum Nicholas Tarantino Nidhi Bhaskar Laura Whiteley Jacob J van den Berg Source Type: research