Overlapping Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy with Mutation in CFI in a Japanese Patient: A Case Report
Intern Med. 2023 Nov 6. doi: 10.2169/internalmedicine.2713-23. Online ahead of print.ABSTRACTA 34-year-old Japanese man presented with blurred vision, headache, nausea, anemia, thrombocytopenia, and severe renal dysfunction. Thrombotic microangiopathy was initially suspected to have been caused by malignant hypertension. Antihypertensive medications did not improve his thrombocytopenia or renal dysfunction, and other diseases causing thrombotic microangiopathy were ruled out. Therefore, the patient was diagnosed with atypical hemolytic uremic syndrome. A renal biopsy revealed an overlap of thrombotic microangiopathy and C3...
Source: Internal Medicine - November 5, 2023 Category: Internal Medicine Authors: Kosuke Osawa Shuto Yamamoto Yukiko Yamano Ayako Kita Kota Okamoto Noritoshi Kato Yoshitaka Tatematsu Fumiyoshi Kojima Masaki Ohya Shigeo Hara Shin-Ichi Murata Norimitsu Inoue Shoichi Maruyama Shin-Ichi Araki Source Type: research

Atypical hemolytic and uremic syndrome in Algeria: diagnostic difficulties and therapeutic constraints
Nephrol Ther. 2023 Nov 2;19(6):483-490. doi: 10.1684/ndt.2023.37.ABSTRACTAtypical Hemolytic Uremic Syndrome (aHUS) is a systemic disease due to dysregulation of the alternate complement pathway, mortality is estimated at 10% and more than 50% of patients progress to end-stage renal disease. The aim of this study was to summarize the clinical data and biological results as well as the evolution and management of patients with aHUS seen over a period of four years in one specialized department in Algeria. Our study was observational and longitudinal. The inclusion criteria were: the clinical-biological triad of aHUS and age ...
Source: Nephrologie and Therapeutique - November 2, 2023 Category: Urology & Nephrology Authors: Souad Chelghoum Farid Haddoum Kamel Djenouhat Mohamed-Taher Hamlaoui Nawel Adjlane Mourad Boukheloua Source Type: research

Atypical hemolytic and uremic syndrome in Algeria: diagnostic difficulties and therapeutic constraints
Nephrol Ther. 2023 Nov 2;19(6):483-490. doi: 10.1684/ndt.2023.37.ABSTRACTAtypical Hemolytic Uremic Syndrome (aHUS) is a systemic disease due to dysregulation of the alternate complement pathway, mortality is estimated at 10% and more than 50% of patients progress to end-stage renal disease. The aim of this study was to summarize the clinical data and biological results as well as the evolution and management of patients with aHUS seen over a period of four years in one specialized department in Algeria. Our study was observational and longitudinal. The inclusion criteria were: the clinical-biological triad of aHUS and age ...
Source: Nephrologie and Therapeutique - November 2, 2023 Category: Urology & Nephrology Authors: Souad Chelghoum Farid Haddoum Kamel Djenouhat Mohamed-Taher Hamlaoui Nawel Adjlane Mourad Boukheloua Source Type: research

Atypical hemolytic and uremic syndrome in Algeria: diagnostic difficulties and therapeutic constraints
Nephrol Ther. 2023 Nov 2;19(6):483-490. doi: 10.1684/ndt.2023.37.ABSTRACTAtypical Hemolytic Uremic Syndrome (aHUS) is a systemic disease due to dysregulation of the alternate complement pathway, mortality is estimated at 10% and more than 50% of patients progress to end-stage renal disease. The aim of this study was to summarize the clinical data and biological results as well as the evolution and management of patients with aHUS seen over a period of four years in one specialized department in Algeria. Our study was observational and longitudinal. The inclusion criteria were: the clinical-biological triad of aHUS and age ...
Source: Nephrologie and Therapeutique - November 2, 2023 Category: Urology & Nephrology Authors: Souad Chelghoum Farid Haddoum Kamel Djenouhat Mohamed-Taher Hamlaoui Nawel Adjlane Mourad Boukheloua Source Type: research

Atypical hemolytic and uremic syndrome in Algeria: diagnostic difficulties and therapeutic constraints
Nephrol Ther. 2023 Nov 2;19(6):483-490. doi: 10.1684/ndt.2023.37.ABSTRACTAtypical Hemolytic Uremic Syndrome (aHUS) is a systemic disease due to dysregulation of the alternate complement pathway, mortality is estimated at 10% and more than 50% of patients progress to end-stage renal disease. The aim of this study was to summarize the clinical data and biological results as well as the evolution and management of patients with aHUS seen over a period of four years in one specialized department in Algeria. Our study was observational and longitudinal. The inclusion criteria were: the clinical-biological triad of aHUS and age ...
Source: Nephrologie and Therapeutique - November 2, 2023 Category: Urology & Nephrology Authors: Souad Chelghoum Farid Haddoum Kamel Djenouhat Mohamed-Taher Hamlaoui Nawel Adjlane Mourad Boukheloua Source Type: research

Atypical hemolytic and uremic syndrome in Algeria: diagnostic difficulties and therapeutic constraints
Nephrol Ther. 2023 Nov 2;19(6):483-490. doi: 10.1684/ndt.2023.37.ABSTRACTAtypical Hemolytic Uremic Syndrome (aHUS) is a systemic disease due to dysregulation of the alternate complement pathway, mortality is estimated at 10% and more than 50% of patients progress to end-stage renal disease. The aim of this study was to summarize the clinical data and biological results as well as the evolution and management of patients with aHUS seen over a period of four years in one specialized department in Algeria. Our study was observational and longitudinal. The inclusion criteria were: the clinical-biological triad of aHUS and age ...
Source: Nephrologie and Therapeutique - November 2, 2023 Category: Urology & Nephrology Authors: Souad Chelghoum Farid Haddoum Kamel Djenouhat Mohamed-Taher Hamlaoui Nawel Adjlane Mourad Boukheloua Source Type: research

Atypical hemolytic and uremic syndrome in Algeria: diagnostic difficulties and therapeutic constraints
Nephrol Ther. 2023 Nov 2;19(6):483-490. doi: 10.1684/ndt.2023.37.ABSTRACTAtypical Hemolytic Uremic Syndrome (aHUS) is a systemic disease due to dysregulation of the alternate complement pathway, mortality is estimated at 10% and more than 50% of patients progress to end-stage renal disease. The aim of this study was to summarize the clinical data and biological results as well as the evolution and management of patients with aHUS seen over a period of four years in one specialized department in Algeria. Our study was observational and longitudinal. The inclusion criteria were: the clinical-biological triad of aHUS and age ...
Source: Nephrologie and Therapeutique - November 2, 2023 Category: Urology & Nephrology Authors: Souad Chelghoum Farid Haddoum Kamel Djenouhat Mohamed-Taher Hamlaoui Nawel Adjlane Mourad Boukheloua Source Type: research

Atypical hemolytic and uremic syndrome in Algeria: diagnostic difficulties and therapeutic constraints
Nephrol Ther. 2023 Nov 2;19(6):483-490. doi: 10.1684/ndt.2023.37.ABSTRACTAtypical Hemolytic Uremic Syndrome (aHUS) is a systemic disease due to dysregulation of the alternate complement pathway, mortality is estimated at 10% and more than 50% of patients progress to end-stage renal disease. The aim of this study was to summarize the clinical data and biological results as well as the evolution and management of patients with aHUS seen over a period of four years in one specialized department in Algeria. Our study was observational and longitudinal. The inclusion criteria were: the clinical-biological triad of aHUS and age ...
Source: Nephrologie and Therapeutique - November 2, 2023 Category: Urology & Nephrology Authors: Souad Chelghoum Farid Haddoum Kamel Djenouhat Mohamed-Taher Hamlaoui Nawel Adjlane Mourad Boukheloua Source Type: research

Atypical hemolytic and uremic syndrome in Algeria: diagnostic difficulties and therapeutic constraints
Nephrol Ther. 2023 Nov 2;19(6):483-490. doi: 10.1684/ndt.2023.37.ABSTRACTAtypical Hemolytic Uremic Syndrome (aHUS) is a systemic disease due to dysregulation of the alternate complement pathway, mortality is estimated at 10% and more than 50% of patients progress to end-stage renal disease. The aim of this study was to summarize the clinical data and biological results as well as the evolution and management of patients with aHUS seen over a period of four years in one specialized department in Algeria. Our study was observational and longitudinal. The inclusion criteria were: the clinical-biological triad of aHUS and age ...
Source: Nephrologie and Therapeutique - November 2, 2023 Category: Urology & Nephrology Authors: Souad Chelghoum Farid Haddoum Kamel Djenouhat Mohamed-Taher Hamlaoui Nawel Adjlane Mourad Boukheloua Source Type: research

Atypical hemolytic and uremic syndrome in Algeria: diagnostic difficulties and therapeutic constraints
Nephrol Ther. 2023 Nov 2;19(6):483-490. doi: 10.1684/ndt.2023.37.ABSTRACTAtypical Hemolytic Uremic Syndrome (aHUS) is a systemic disease due to dysregulation of the alternate complement pathway, mortality is estimated at 10% and more than 50% of patients progress to end-stage renal disease. The aim of this study was to summarize the clinical data and biological results as well as the evolution and management of patients with aHUS seen over a period of four years in one specialized department in Algeria. Our study was observational and longitudinal. The inclusion criteria were: the clinical-biological triad of aHUS and age ...
Source: Nephrologie and Therapeutique - November 2, 2023 Category: Urology & Nephrology Authors: Souad Chelghoum Farid Haddoum Kamel Djenouhat Mohamed-Taher Hamlaoui Nawel Adjlane Mourad Boukheloua Source Type: research

Atypical hemolytic and uremic syndrome in Algeria: diagnostic difficulties and therapeutic constraints
Nephrol Ther. 2023 Nov 2;19(6):483-490. doi: 10.1684/ndt.2023.37.ABSTRACTAtypical Hemolytic Uremic Syndrome (aHUS) is a systemic disease due to dysregulation of the alternate complement pathway, mortality is estimated at 10% and more than 50% of patients progress to end-stage renal disease. The aim of this study was to summarize the clinical data and biological results as well as the evolution and management of patients with aHUS seen over a period of four years in one specialized department in Algeria. Our study was observational and longitudinal. The inclusion criteria were: the clinical-biological triad of aHUS and age ...
Source: Nephrologie and Therapeutique - November 2, 2023 Category: Urology & Nephrology Authors: Souad Chelghoum Farid Haddoum Kamel Djenouhat Mohamed-Taher Hamlaoui Nawel Adjlane Mourad Boukheloua Source Type: research

Atypical hemolytic and uremic syndrome in Algeria: diagnostic difficulties and therapeutic constraints
Nephrol Ther. 2023 Nov 2;19(6):483-490. doi: 10.1684/ndt.2023.37.ABSTRACTAtypical Hemolytic Uremic Syndrome (aHUS) is a systemic disease due to dysregulation of the alternate complement pathway, mortality is estimated at 10% and more than 50% of patients progress to end-stage renal disease. The aim of this study was to summarize the clinical data and biological results as well as the evolution and management of patients with aHUS seen over a period of four years in one specialized department in Algeria. Our study was observational and longitudinal. The inclusion criteria were: the clinical-biological triad of aHUS and age ...
Source: Nephrologie and Therapeutique - November 2, 2023 Category: Urology & Nephrology Authors: Souad Chelghoum Farid Haddoum Kamel Djenouhat Mohamed-Taher Hamlaoui Nawel Adjlane Mourad Boukheloua Source Type: research

Atypical hemolytic and uremic syndrome in Algeria: diagnostic difficulties and therapeutic constraints
Nephrol Ther. 2023 Nov 2;19(6):483-490. doi: 10.1684/ndt.2023.37.ABSTRACTAtypical Hemolytic Uremic Syndrome (aHUS) is a systemic disease due to dysregulation of the alternate complement pathway, mortality is estimated at 10% and more than 50% of patients progress to end-stage renal disease. The aim of this study was to summarize the clinical data and biological results as well as the evolution and management of patients with aHUS seen over a period of four years in one specialized department in Algeria. Our study was observational and longitudinal. The inclusion criteria were: the clinical-biological triad of aHUS and age ...
Source: Nephrologie and Therapeutique - November 2, 2023 Category: Urology & Nephrology Authors: Souad Chelghoum Farid Haddoum Kamel Djenouhat Mohamed-Taher Hamlaoui Nawel Adjlane Mourad Boukheloua Source Type: research

Atypical hemolytic and uremic syndrome in Algeria: diagnostic difficulties and therapeutic constraints
Nephrol Ther. 2023 Nov 2;19(6):483-490. doi: 10.1684/ndt.2023.37.ABSTRACTAtypical Hemolytic Uremic Syndrome (aHUS) is a systemic disease due to dysregulation of the alternate complement pathway, mortality is estimated at 10% and more than 50% of patients progress to end-stage renal disease. The aim of this study was to summarize the clinical data and biological results as well as the evolution and management of patients with aHUS seen over a period of four years in one specialized department in Algeria. Our study was observational and longitudinal. The inclusion criteria were: the clinical-biological triad of aHUS and age ...
Source: Nephrologie and Therapeutique - November 2, 2023 Category: Urology & Nephrology Authors: Souad Chelghoum Farid Haddoum Kamel Djenouhat Mohamed-Taher Hamlaoui Nawel Adjlane Mourad Boukheloua Source Type: research