Optical Real-Time Cardiorenal Toxin Uric Acid Measurement During Hemodialysis Using a Miniaturized Optical Sensor
In this study, the authors tested a miniaturized optical sensor for monitoring uric acid levels and removal for the first time in a more extensive clinical study, including Hemodialysis (HD) and Post-dilutional online hemodiafiltration (HDF) procedures with different settings in Tallinn, Estonia. The results (Mean±SD, Lab vs. Sensor) of the uric acid concentration 57.20±34.05 vs. 57.22±33.09 µmol/L, reduction ratio 68.72±10.91 vs. 67.89±12.48 %, and total removed amount 7.00±2.10 vs. 7.33±2.29 mmol did not differ significantly from the values obtained from the clinical laboratory (p<0.05).Clinical Relevance-Duri...
Source: Molecular Medicine - December 12, 2023 Category: Molecular Biology Authors: Jana Holmar Jurgen Arund Annika Adoberg Liisi Leis Merike Luman Joosep Paats Kristjan Pilt Risto Tanner Ivo Fridolin Source Type: research
Optical Real-Time Cardiorenal Toxin Uric Acid Measurement During Hemodialysis Using a Miniaturized Optical Sensor
In this study, the authors tested a miniaturized optical sensor for monitoring uric acid levels and removal for the first time in a more extensive clinical study, including Hemodialysis (HD) and Post-dilutional online hemodiafiltration (HDF) procedures with different settings in Tallinn, Estonia. The results (Mean±SD, Lab vs. Sensor) of the uric acid concentration 57.20±34.05 vs. 57.22±33.09 µmol/L, reduction ratio 68.72±10.91 vs. 67.89±12.48 %, and total removed amount 7.00±2.10 vs. 7.33±2.29 mmol did not differ significantly from the values obtained from the clinical laboratory (p<0.05).Clinical Relevance-Duri...
Source: Molecular Medicine - December 12, 2023 Category: Molecular Biology Authors: Jana Holmar Jurgen Arund Annika Adoberg Liisi Leis Merike Luman Joosep Paats Kristjan Pilt Risto Tanner Ivo Fridolin Source Type: research
Brazilian Dialysis Survey 2022
CONCLUSIONS: The absolute number and prevalence rate of patients on chronic dialysis continue to increase. A growing number of patients were receiving hemodiafiltration. The mortality rate decreased, probably due to the end of COVID-19 pandemic. The conclusions were drawn in the context of relatively low voluntary participation, which imposed methodological limitations on our estimates.PMID:38078834 | DOI:10.1590/2175-8239-JBN-2023-0062en (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - December 11, 2023 Category: Urology & Nephrology Authors: Fabiana Baggio Nerbass Helbert do Nascimento Lima Jos é Andrade Moura-Neto Jocemir Ronaldo Lugon Ricardo Sesso Source Type: research
Body fluid volume calculated using the uric acid kinetic model relates to the vascular event
ConclusionsExtracellular volume calculated using the uric acid kinetic model method is a prognostic factor for vascular events in patients undergoing hemodialysis. (Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - December 11, 2023 Category: Transplant Surgery Source Type: research
Hemoadsorption therapy for calcium channel blocker overdose: A case report
Background: Modern resin hemoadsorption/hemoperfusion (HP) for calcium channel blocker (CCB) overdose is yet to be reported. The characteristics of CCBs make them unamenable to removal by haemodiafiltration or charcoal hemoperfusion, however, elimination, using styrene bead adsorption in an ex-vivo model has been demonstrated. Its clinical use is described.Case report: A male in his twenties was admitted with shock into the Intensive Care Unit (ICU), following an overdose of amlodipine and risperidone. (Source: The Journal of Emergency Medicine)
Source: The Journal of Emergency Medicine - December 8, 2023 Category: Emergency Medicine Authors: Shahed Omar, Pano Parris, Chloe Rose Gurke Tags: Selected Topics: Toxicology Source Type: research
Removal characteristics of presepsin by operating conditions and hemofilter
AbstractPresepsin, which is used as a biomarker for sepsis, is thought to be removed by dialysis, but the actual removal properties of dialysis are unknown. We investigated the presepsin removal properties of continuous hemodiafiltration using the high concentration of presepsin from human plasma drained by plasma exchange. Each solution in plasma exchange was connected to a continuous hemodiafiltration blood circuit and circulated at 4 conditions. The results show that presepsin was confirmed to be removed more efficiently in hemofiltration than in hemodialysis. In addition, when using a polymethylmethacrylate hemofilter ...
Source: Journal of Artificial Organs - December 5, 2023 Category: Transplant Surgery Source Type: research
