Bayesian Optimization-Based Inverse Finite Element Analysis for Atrioventricular Heart Valves
In this study, our key contributions include: (i) a first-of-its-kind demonstration of the BO method used for the AHV iFEA; and (ii) the evaluation of a candidate AHV in-silico modeling approach wherein the chordae could be substituted with equivalent displacement boundary conditions, rendering the better iFEA convergence and a smoother objective surface.PMID:37989903 | DOI:10.1007/s10439-023-03408-6 (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - November 22, 2023 Category: Biomedical Engineering Authors: Colton J Ross Devin W Laurence Ankush Aggarwal Ming-Chen Hsu Arshid Mir Harold M Burkhart Chung-Hao Lee Source Type: research

Crosslinking strategies of decellularized extracellular matrix in tissue regeneration
J Biomed Mater Res A. 2023 Nov 22. doi: 10.1002/jbm.a.37650. Online ahead of print.ABSTRACTBy removing the immunogenic cellular components through various decellularization methods, decellularized extracellular matrix (dECM) is considered a promising material in the field of tissue engineering and regenerative medicine with highly preserved physicochemical properties and superior biocompatibility. However, decellularization treatment can lead to some loss of structural integrity, mechanical strength, degradation stability, and biological performance of dECM biomaterials. Therefore, physical and chemical crosslinking method...
Source: Biomed Res - November 22, 2023 Category: Research Authors: Su Qiao Tan Peijie Jiang Nan Source Type: research

Bayesian Optimization-Based Inverse Finite Element Analysis for Atrioventricular Heart Valves
In this study, our key contributions include: (i) a first-of-its-kind demonstration of the BO method used for the AHV iFEA; and (ii) the evaluation of a candidate AHV in-silico modeling approach wherein the chordae could be substituted with equivalent displacement boundary conditions, rendering the better iFEA convergence and a smoother objective surface.PMID:37989903 | DOI:10.1007/s10439-023-03408-6 (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - November 22, 2023 Category: Biomedical Engineering Authors: Colton J Ross Devin W Laurence Ankush Aggarwal Ming-Chen Hsu Arshid Mir Harold M Burkhart Chung-Hao Lee Source Type: research

Crosslinking strategies of decellularized extracellular matrix in tissue regeneration
J Biomed Mater Res A. 2023 Nov 22. doi: 10.1002/jbm.a.37650. Online ahead of print.ABSTRACTBy removing the immunogenic cellular components through various decellularization methods, decellularized extracellular matrix (dECM) is considered a promising material in the field of tissue engineering and regenerative medicine with highly preserved physicochemical properties and superior biocompatibility. However, decellularization treatment can lead to some loss of structural integrity, mechanical strength, degradation stability, and biological performance of dECM biomaterials. Therefore, physical and chemical crosslinking method...
Source: Biomed Res - November 22, 2023 Category: Research Authors: Su Qiao Tan Peijie Jiang Nan Source Type: research

Bayesian Optimization-Based Inverse Finite Element Analysis for Atrioventricular Heart Valves
In this study, our key contributions include: (i) a first-of-its-kind demonstration of the BO method used for the AHV iFEA; and (ii) the evaluation of a candidate AHV in-silico modeling approach wherein the chordae could be substituted with equivalent displacement boundary conditions, rendering the better iFEA convergence and a smoother objective surface.PMID:37989903 | DOI:10.1007/s10439-023-03408-6 (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - November 22, 2023 Category: Biomedical Engineering Authors: Colton J Ross Devin W Laurence Ankush Aggarwal Ming-Chen Hsu Arshid Mir Harold M Burkhart Chung-Hao Lee Source Type: research