Declining Cardiovascular Mortality in Atrial Fibrillation Patients
A downward trend in cardiovascular mortality has prevailed for some time now, and we might take the data here as an example of ways in which improved options for detection and treatment produce results in specific portions of the patient population. Also worthy of note is the point that these older patients have many issues, and while slowing the pace of cardiovascular decline with age should have beneficial effects throughout the body, reduced cardiovascular mortality due to improved treatment that specifically focuses on cardiovascular disease allows other age-related conditions to claim a greater proportion of the popul...
Source: Fight Aging! - September 1, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Unveiling alcohol ’ s health paradox: heart benefits and detrimental effects
Tons of ink have been expended on the health effects, both positive and negative, of alcohol consumption. Beneficial effects on the heart were discussed in the 1990s based on the “French paradox.” A paper published in 1995 noted that there was less ischemic heart disease in France compared to the U.S., despite higher saturated fat Read more… Unveiling alcohol’s health paradox: heart benefits and detrimental effects originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - August 30, 2023 Category: General Medicine Authors: Tags: Conditions Psychiatry Source Type: blogs

Fight Aging! Newsletter, August 28th 2023
In conclusion, we identified 20 genes with significant evolutionary signals unique to long-lived species, which provided new insight into the lifespan extension of mammals and might bring new strategies to extend human lifespan. « Back to Top Trials of Xenotransplantation of Pig Organs into Humans Continue https://www.fightaging.org/archives/2023/08/trials-of-xenotransplantation-of-pig-organs-into-humans-continue/ Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants i...
Source: Fight Aging! - August 27, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Longevity-Associated Variant of BPIFB4 Reduces Heart Disease Severity
Few human longevity-associated gene variants are replicated in multiple patient populations. One of those is a variant of BPIFB4, that appears to improve immune function and lower inflammation by adjusting the behavior of macrophage cells of the innate immune system. Delivering the variant to mice using a gene therapy has similar effects. It may well operate via other mechanisms as well, however. Few proteins in a living cell turn out to have only one purpose. In today's open access paper, researchers report that the BPIFB4 variant reduces the severity of coronary artery disease in humans and mice. Delivering the va...
Source: Fight Aging! - August 25, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

This Humble Vegetable Reduces Heart Disease Risk
A vitamin found in this superfood can protect against heart disease by preventing cholesterol plaque build-up in the arteries. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - August 22, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Heart Disease Source Type: blogs

Eat These 6 Healthy Foods To Avoid Heart Disease
Eating these 6 foods will protect you from heart disease, stroke, and death. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - August 21, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Heart Disease Source Type: blogs

The Drinking Habit Linked To Killer Strokes And Cardiac Arrest
These popular drinks can cause heart problems, mood disorder, psychosis, stroke, and death. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - August 21, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Heart Disease Source Type: blogs

Fight Aging! Newsletter, August 21st 2023
This study aimed to investigate the association between frailty index and circulating CAP2 concentration in 467 community-dwelling older adults (median age: 79; range: 65-92 years). The selected robust regression model showed that circulating CAP2 concentration was not associated with chronological age, as well as sex and education. However, circulating CAP2 concentration was significantly and inversely associated with the frailty index: a 0.1-unit increase in frailty index leads to ~0.5-point mean decrease in CAP2 concentration. Furthermore, mean CAP2 concentration was significantly lower in frail participants (i.e., fr...
Source: Fight Aging! - August 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

How To Live Longer: 8 Delicious Foods That Add Years To Your Life
Foods rich in this type of omega-3 fatty acid found to reduce risk of death, especially from coronary heart disease. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - August 20, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Heart Disease Source Type: blogs

This Vitamin Increases The Risk Of Heart Disease And Stroke
People who take too much of this vitamin are more likely to have a heart attack or a stroke. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - August 20, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Heart Disease Source Type: blogs

Progress Towards Therapies for Transthyretin Amyloidosis
Transthyretin is one of the few proteins in the body that can misfold in a way that encourages other copies of the protein to also misfold, forming solid aggregates called amyloid that disrupt tissue structure and function. The resulting condition, transthyretin amyloidosis, clogs up cardiac tissue and thereby contributes to a fraction of all heart failure cases. It is thought to be a major cause of mortality in supercentenarians. Approved therapies targeting a more aggressive form of the condition resulting from a mutated transthyretin gene will not be useful against the much more common version of the condition, as they ...
Source: Fight Aging! - August 18, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

THCB 20th Birthday Classic:  As I’ve always suspected, Health Care = Communism + Frappuccinos
By MATTHEW HOLT Our 20th birthday continues with a few classics coming out. Back in 2005 I was really cutting a lyrical rug, and would never miss a chance to get that Cambridge training in Marxism into use. This essay about whether health care should be a public or private good has always been one of my favorites, even if I’m not sure Starbucks is still making Frappuccinos. And 18 years later the basic point of this essay remains true, even if many of you will not have a clue who Vioxx or Haliburton were or why they mattered back then! Those of you who think I’m an unreconstructed commie will correctly suspec...
Source: The Health Care Blog - August 15, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Matthew Holt Communism Frappuccinos Source Type: blogs

Best Blood Pressure Monitors For Apple Health
In conclusion, Apple Health and compatible blood pressure monitors represent the synergy between technology and healthcare, redefining health management’s future. This amalgamation fosters a detailed and proactive perspective toward personal health, emphasizing the need for maintaining awareness and making educated health choices. As technological advancements persist, our capacity to control and comprehend our health will likewise expand, heralding a new age of customized healthcare. Reference Central-acting agents – Drugs.com. (n.d.). Retrieved July 24, 2023, from https://www.drugs.com/mca/central-ac...
Source: The EMT Spot - August 14, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Monitors Source Type: blogs

Survivors of Nuclear Weapon Use in Early Life Exhibit Accelerated Immune Aging in Late Life
It probably strains the meaning of the term to call the aftermath of the use of nuclear weapons at the end of the Second World War a natural experiment, but nonetheless there has been considerable study of survivors from those events and their health relative to control populations in other parts of Japan. Irradiation is known to produce what is effectively accelerated aging in the context of cancer treatment, producing an increased burden of senescent cells that then ensure the later course of health for survivors is worse than would otherwise be the case, absent both cancer and treatment. In the case of exposure to radia...
Source: Fight Aging! - August 14, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Heart disease in the shadows: a closer look at cardiac sarcoidosis
My new internist began my annual checkup with a nervous confession: “You are my first patient with cardiac sarcoidosis.” Even during an urgent care visit for potential cellulitis, I was met with raised eyebrows from the treating physician who reviewed my chart: “Very interesting, I’ve never seen a case of this heart disease.” With over Read more… Heart disease in the shadows: a closer look at cardiac sarcoidosis originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - August 14, 2023 Category: General Medicine Authors: Tags: Conditions Rheumatology Source Type: blogs