Study Supports Opdivo as Second-Line Mesothelioma Treatment
When the effectiveness of first-line chemotherapy fails and malignant mesothelioma returns, more patients could soon turn with confidence to a proven, second-line treatment.
The first phase III, placebo-controlled, double-blind clinical trial studying the safety and efficacy of Opdivo, the immunotherapy drug known generically as nivolumab, has raised the level of confidence in this option for patients with relapsed disease.
“The evidence is robust, the survival significant,” Dr. Dean Fennell, chair of Thoracic Medical Oncology, University of Leicester and University Hospitals in the United Kingdom, told The Mesot...
Source: Asbestos and Mesothelioma News - November 2, 2021 Category: Environmental Health Authors: Fran Mannino Source Type: news
CT finds secondary lung disease in head and neck cancer survivors
Survivors of head and neck cancer have a 2.5 times higher risk of developin...Read more on AuntMinnie.comRelated Reading:
Shorter follow-up for lung lesions equals better outcomes
Could scanning more Black people boost benefits of lung screening?
CT lung cancer screening guidelines are changing
Rural areas lack access to CT lung cancer screening
AI predicts cardiovascular risk on LDCT lung cancer screening (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - October 28, 2021 Category: Radiology Source Type: news
Galera's stock plunges 73% on disappointing test results for lead cancer drug candidate
Galera Therapeutics stock plunged by more than 70% Tuesday after the Malvern biopharmaceutical firm said its lead experimental cancer therapy failed to meet its primary endpoint in late-stage clinical testing.
The new drug candidate, called GC4419, is under development as a treatment for severe oral mucositis in patients with locally advanced head and neck cancer undergoing radiotherapy.
The trial did not meet its primary endpoint of reduction in the incidence of severe oral mucositis, a condition… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - October 19, 2021 Category: Biotechnology Authors: John George Source Type: news
New treatment destroys head and neck cancer tumours in trial
Exclusive: combination of drugs causes tumours to vanish in some terminally ill patients, study findsA new cancer treatment can wipe out tumours in terminally ill head and neck cancer patients, scientists have discovered.In a landmark trial, a cocktail of immunotherapy medications harnessed patients ’ immune systems to kill their own cancer cells and prompted “a positive trend in survival”, according to researchers at the Institute of Cancer Research (ICR), London, and the Royal Marsden NHS foundation trust.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - October 11, 2021 Category: Science Authors: Andrew Gregory Health editor Tags: Cancer Medical research Health Science NHS UK news Source Type: news
Risk of suicidal self-directed violence among US veteran survivors of head and neck cancer - Nugent SM, Morasco BJ, Handley R, Clayburgh D, Hooker ER, Ganzini L, Knight SJ, Chen JI, Sullivan DR, Slatore CG.
IMPORTANCE: Head and neck cancer (HNC) survivors are about twice as likely to die by suicide compared with other cancer survivors. OBJECTIVE: To examine the associations between precancer mental health and pain and postcancer receipt of mental heal... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news
Nanobiotix highlights ASTRO research studies
Nanobiotix will present results from clinical trials of its NBTXR3 radioenhance...Read more on AuntMinnie.comRelated Reading:
ASTRO to require masks at October annual meeting
PET/CT shows promise predicting outcomes in head, neck cancer
ASTRO commits to October in-person annual meeting in Chicago
RT + immunotherapy = head/neck cancer treatment option
Nanobiotix plans head and neck cancer treatment trial (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - October 7, 2021 Category: Radiology Source Type: news
Nivolumab more effective, but too costly, for head and neck cancer in Brazil
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - October 1, 2021 Category: Drugs & Pharmacology Source Type: news
The multidimensional prognostic index as a measure of frailty in elderly patients with head and neck cancer - Bakas AT, Sewnaik A, van Straaten J, Baatenburg de Jong RJ, Mattace-Raso FUS, Polinder-Bos HA.
PURPOSE: The multidimensional prognostic index (MPI) is a prognostic model derived from the comprehensive geriatric assessment (CGA) which can predict 1-year mortality risk in elderly individuals. We hypothesized that the MPI also reflects the degree of fr... (Source: SafetyLit)
Source: SafetyLit - September 27, 2021 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
What 9/11 Survivors and First Responders Have Taught Us About Public Health in the 20 Years Since the Attacks
Dr. David Prezant was knocked fully airborne at 9:59 on the morning of Sept. 11, 2001. He didn’t see the impact coming, but he felt it when it hit—and it nearly killed him.
Little more than an hour earlier, Prezant, then the deputy chief medical officer of the Fire Department of New York, was headed for his usual workplace at the FDNY’s Office of Medical Affairs, just across the Manhattan Bridge in Brooklyn. He had already heard that a plane had hit the North Tower of the World Trade Center, and he reckoned that it was an accident. By the time he reached his office, however, the South Tower had been struc...
Source: TIME: Health - September 10, 2021 Category: Consumer Health News Authors: Jeffrey Kluger and Tara Law Tags: Uncategorized healthscienceclimate Source Type: news
Human Papillomavirus-Associated Head and Neck Cancer Human Papillomavirus-Associated Head and Neck Cancer
Review the epidemiology, screening, presentation, diagnosis, prognosis, and prevention of HPV-positive oropharyngeal squamous cell carcinoma, with a focus on the primary care provider ' s role.Journal of the American Board of Family Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 2, 2021 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news
NIDCR's Fall 2021 E-Newsletter
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NIDCR's Fall 2021 E-Newsletter
In this issue:
NIDCR News
Funding Opportunities & Related Notices
NIH/HHS News
Subscribe to NICDR News
Science Advances
NIDCR News
5 Q&As About “Oral Health in America: Advances and Challenges”
NIDCR issued a brief Q&A regarding details of the forthcoming report Oral Health in America: Advances and Challenges, which will be published in Fall 2021. This comprehensive report will examine improvements in oral health over the past two decad...
Source: NIDCR Science News - September 1, 2021 Category: Dentistry Source Type: news
Suicide Risk Found to be Significantly High in Head And Neck Cancer, Especially in Rural Populations
Summarizes the findings of a study on death by suicide in head and neck cancer patients, noting 50% higher rates of suicide for rural patients. Reports that the majority of the 405 reported deaths by suicide were among non-Hispanic males and that the median time between diagnosis and suicide was 26 months. Discusses the implications of these findings on suicide prevention and rural health nationwide. (Source: News stories via the Rural Assistance Center)
Source: News stories via the Rural Assistance Center - August 7, 2021 Category: Rural Health Source Type: news
Re: More evidences are needed in reducing the suicide risk in head and neck cancer patients - Twigg JA, Anderson JM, Humphris G, Nixon I, Rogers SN, Kanatas A.
We thank the authors for their interest in our review paper 'Best practice in reducing the suicide risk in head and neck cancer patients: a structured review' and for their constructive and insightful comments. While there are multiple observational studie... (Source: SafetyLit)
Source: SafetyLit - July 28, 2021 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
Incidence and risk of suicide among patients with head and neck cancer in rural, urban, and metropolitan areas - Osazuwa-Peters N, Barnes JM, Okafor SI, Taylor DB, Hussaini AS, Adjei Boakye E, Simpson MC, Graboyes EM, Lee WT.
IMPORTANCE: Patients with head and neck cancer (HNC) are known to be at increased risk of suicide compared with the general population, but there has been insufficient research on whether this risk differs based on patients' rural, urban, or metropolitan r... (Source: SafetyLit)
Source: SafetyLit - July 27, 2021 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
Head, neck cancer patients at up to 5-fold higher risk for suicide compared to general population, study finds
People with head and neck cancers have an up to five times higher risk for suicide compared to the general population, an analysis published Friday by JAMA Otolaryngology-Head and Neck Surgery found. (Source: Health News - UPI.com)
Source: Health News - UPI.com - July 23, 2021 Category: Consumer Health News Source Type: news
