A Prospective Study to Evaluate Clinical Outcomes in Anti-LGI1 Encephalitis
Conditions: Autoimmune Encephalitis; Leucine-Rich Glioma Inactivated 1 Autoimmune Encephalitis Sponsors: Second Affiliated Hospital, School of Medicine, Zhejiang University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 15, 2023 Category: Research Source Type: clinical trials
FET PET in Differentiating Tumour Progression From Pseudoprogression in High Grade Glioma
Conditions: Glioma, Malignant Interventions: Diagnostic Test: FET PET Sponsors: Singapore General Hospital; National Cancer Centre, Singapore; National Neuroscience Institute Singapore; Duke-NUS Centre of Quantitative Medicine; Duke-NUS Khoo Pilot Award (Collaborative) 2021 Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 15, 2023 Category: Research Source Type: clinical trials
Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma
Conditions: Glioma, Malignant; New Diagnosis Tumor Interventions: Biological: NSC-CRAd-S-pk7; Dietary Supplement: N-acetylcysteine amide (NACA) Sponsors: Northwestern University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 13, 2023 Category: Research Source Type: clinical trials
PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications
Conditions: Glioma; Medulloblastoma; Ependymoma Interventions: Drug: PLX038 Sponsors: National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 8, 2023 Category: Research Source Type: clinical trials
Recurrent High Grade Glioma Treated by LITT
Conditions: Recurrent High Grade Glioma Interventions: Device: LITT; Other: Control Sponsors: Beijing Tiantan Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 8, 2023 Category: Research Source Type: clinical trials
Study of Olutasidenib and Temozolomide in HGG
Conditions: High Grade Glioma; Astrocytoma; Astrocytoma, Grade III; Astrocytoma, Grade IV; Diffuse Intrinsic Pontine Glioma; WHO Grade III Glioma; WHO Grade IV Glioma; Metastatic Brain Tumor; Diffuse Midline Glioma, H3 K27M-Mutant; Thalamus Tumor; Spinal Tumor; IDH1 Mutation; IDH1 R132; IDH1 R132C; IDH1 R132H; IDH1 R132S; IDH1 R132G; IDH1 R132L; Oligodendroglioma Interventions: Drug: Olutasidenib + TMZ Sponsors: Nationwide Children ' s Hospital; Rigel Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 8, 2023 Category: Research Source Type: clinical trials
Retifanlimab With Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma
Conditions: Recurrent Glioblastoma; Recurrent WHO Grade 4 Glioma Interventions: Biological: Bevacizumab; Procedure: Biospecimen Collection; Procedure: Computed Tomography; Other: Electronic Health Record Review; Radiation: Hypofractionated Radiation Therapy; Procedure: Magnetic Resonance Imaging; Biological: Retifanlimab Sponsors: Academic and Community Cancer Research United; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 7, 2023 Category: Research Source Type: clinical trials
Phase II Trial of Binimetinib in Patients With BRAF Fusion-positive Low-grade Glioma or Pancreatic Cancer (Perfume)
Conditions: Low-grade Glioma; Pancreatic Cancer Interventions: Drug: Binimetinib 15 MG Sponsors: National Cancer Center, Japan; Ono Pharmaceutical Co. Ltd Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 6, 2023 Category: Research Source Type: clinical trials
Binimetinib in Patients With BRAF Fusion-positive Low-grade Glioma or Pancreatic Cancer (Perfume)
Conditions: Low-grade Glioma; Pancreatic Cancer Interventions: Drug: Binimetinib 15 MG Sponsors: National Cancer Center, Japan; Ono Pharmaceutical Co. Ltd Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 6, 2023 Category: Research Source Type: clinical trials
The Role of B7-H4 in Tumor Vaccine
Conditions: Glioma Interventions: Biological: tumor vaccine Sponsors: Huashan Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 5, 2023 Category: Research Source Type: clinical trials
[18F]BF3-BPA Injection for PET Imaging Study of Gliomas in the Brain
Conditions: Cerebral Gliosis; Positron Emission Tomography Interventions: Radiation: [18F]BF3-BPA Injection for PET Imaging Sponsors: Huashan Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 28, 2023 Category: Research Source Type: clinical trials
The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)
Conditions: Glioblastoma; Glioblastoma, IDH-wildtype; Glioblastoma Multiforme; Glioblastoma Multiforme, Adult; Glioblastoma Multiforme of Brain Interventions: Procedure: Tumor resection; Procedure: Tumor biopsy Sponsors: Jasper Gerritsen; Haaglanden Medical Centre; Universitaire Ziekenhuizen KU Leuven; University Hospital Heidelberg; Technical University of Munich; Insel Gruppe AG, University Hospital Bern; Massachusetts General Hospital; University of California, San Francisco Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 27, 2023 Category: Research Source Type: clinical trials
The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203)
Conditions: Glioblastoma; Glioblastoma Multiforme; Glioblastoma, IDH-wildtype; Glioblastoma Multiforme, Adult Interventions: Behavioral: Palliative Care; Procedure: Tumor biopsy; Procedure: Tumor resection Sponsors: Jasper Gerritsen; Haaglanden Medical Centre; Universitaire Ziekenhuizen KU Leuven; University Hospital Heidelberg; Technical University of Munich; Insel Gruppe AG, University Hospital Bern; Massachusetts General Hospital; University of California, San Francisco Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 27, 2023 Category: Research Source Type: clinical trials
The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma
Conditions: Brain Network Connectivity; Postoperative Delirium; Dexmedetomidine; Propofol Interventions: Drug: Dexmedetomidine; Drug: Propofol Sponsors: Beijing Tiantan Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 18, 2023 Category: Research Source Type: clinical trials
New Analyses from Pivotal Phase 3 INDIGO Study Reinforce Vorasidenib's Potential to Change the Treatment Paradigm for IDH-Mutant Diffuse Glioma
Late-breaking analysis from pivotal INDIGO Phase 3 trial demonstrates vorasidenib led to tumor shrinkage in IDH1/2-mutant diffuse glioma
First data from Phase 1 trial show the safety and tolerability of vorasidenib plus KEYTRUDA®... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - November 18, 2023 Category: Pharmaceuticals Source Type: clinical trials
