A Biomarker-Guided Phase 2 Study of DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) Extended-Release Tablets
Conditions: High Grade Glioma; Anaplastic Astrocytoma Interventions: Drug: DB107-RRV; Drug: DB107-FC Sponsors: Ashish Shah; Denovo Biopharma LLC; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 19, 2024 Category: Research Source Type: clinical trials
Niraparib and Temozolomide in Patients Glioblastoma
Conditions: Glioma, Malignant Interventions: Drug: Temodal; Drug: Niraparib Sponsors: Armando Santoro, MD; Istituto Clinico Humanitas; GlaxoSmithKline Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 14, 2024 Category: Research Source Type: clinical trials
Safety and Efficacy Study for DC Vaccine in Recurrent or Progressive High-grade Gliomas
Conditions: WHO Grade III Gliomas; WHO Grade IV Gliomas Interventions: Biological: personalized dendritic cell injection ZSNeo-DC1.1 Sponsors: Beijing Tiantan Hospital; ZhongSheng BioTech Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 12, 2024 Category: Research Source Type: clinical trials
Ga-68 Prostate Specific Membrane Antigen PET/CT in Gliomas
Conditions: Glioma; Astrocytoma; Anaplastic Astrocytoma; Oligodendroglioma; Glioblastoma Multiforme Interventions: Diagnostic Test: PSMA PET-CT Sponsors: All India Institute of Medical Sciences, Bhubaneswar Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 5, 2024 Category: Research Source Type: clinical trials
CXCR4 PET/MRI Targeted Imaging for Grading Diagnosis, Molecular Typing, and Prognostic Evaluation of Brain Glioma
Conditions: Glioma Interventions: Diagnostic Test: CXCR4 Sponsors: Xiao Chen Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 31, 2024 Category: Research Source Type: clinical trials
Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG
Conditions: DIPG Brain Tumor; Diffuse Intrinsic Pontine Glioma Interventions: Biological: B7H3 specific CAR T cell with IL-7Ra signaling domain Sponsors: Chulalongkorn University; King Chulalongkorn Memorial Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 24, 2024 Category: Research Source Type: clinical trials
A Novel Target Delineation Scheme in High-grade Glioma Patients: a Randomized Single-blind Clinical Trial
Conditions: Radiation Toxicity; MRI Simulated Positioning; High Grade Glioma; Progression-free Survival; Overall Survival Interventions: Radiation: reduced target volume; Radiation: EORTC (European organisation for research and treatment of cancer) target volume Sponsors: Zhujiang Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials
A Study of 68Ga-PSMA-11 PET Scans in People With Brain Tumors
Conditions: High-grade Glioma; Brain Metastases; Brain Metastases, Adult Interventions: Diagnostic Test: 68Ga-PSMA-11 PET Scans Sponsors: Memorial Sloan Kettering Cancer Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Monitoring of Patients With Diffuse Gliomas Using Circulating miRNAs
Conditions: Glioma, Malignant Interventions: Diagnostic Test: Blood sample Sponsors: University Hospital, Caen Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 12, 2024 Category: Research Source Type: clinical trials
Study of Adaptive Radiotherapy for High-grade Glioma Based on Interfraction MRI
Conditions: High-grade Glioma Interventions: Device: adaptive radiotherapy Sponsors: West China Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2024 Category: Research Source Type: clinical trials
Development and Validation of a Deep Learning-Based Survival Prediction Model for Pediatric Glioma Patients: A Retrospective Study Using the SEER Database and Chinese Data
Conditions: Glioma Interventions: Other: Survival state Sponsors: Tang-Du Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2024 Category: Research Source Type: clinical trials
Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma Patients
Conditions: Glioma, Malignant Interventions: Drug: Rivaroxaban 10 MG; Drug: Placebo Sponsors: Nanfang Hospital, Southern Medical University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2024 Category: Research Source Type: clinical trials
The Safety and Effectiveness of NV-A01 in Glioma Patients
Conditions: Advanced Glioblastoma Patients Interventions: Drug: Recombinant NV-A01 adenovirus injection Sponsors: First Affiliated Hospital of Wannan Medical College Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 5, 2024 Category: Research Source Type: clinical trials
Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1)
Conditions: Recurrent Malignant Glioma; Glioblastoma Multiforme of Brain; Gliosarcoma of Brain; Anaplastic Astrocytoma of Brain Interventions: Drug: C134 Re-Administration Sponsors: University of Alabama at Birmingham Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 5, 2024 Category: Research Source Type: clinical trials
Short Term Outcomes After PRoton And photoN radiOtherapy for IDH Mutated Grade 2 and 3 Gliomas
Conditions: Glioma; Radiotherapy; Complications Sponsors: Erasmus Medical Center; Medical Center Haaglanden; Leiden University Medical Center; HollandPTC; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Institute Verbeeten; Universitaire Ziekenhuizen KU Leuven; Maastro Clinic, The Netherlands; University Medical Center Groningen Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 22, 2023 Category: Research Source Type: clinical trials
