The MAVS Immune Recognition Pathway in Viral Infection and Sepsis.
It is estimated that close to 50 million cases of sepsis result in over 11 million annual fatalities worldwide. The pathognomonic feature of sepsis is a dysregulated inflammatory response arising from viral, bacterial, or fungal infections. Immune recognition of pathogen-associated molecular patterns is a hallmark of the host immune defense to combat microbes and to prevent the progression to sepsis. Mitochondrial antiviral signaling protein (MAVS) is a ubiquitous adaptor protein located at the outer mitochondrial membrane, which is activated by the cytosolic pattern recognition receptors, retinoic acid-inducible gene I (R...
Source: Current Awareness Service for Health (CASH) - December 8, 2021 Category: Consumer Health News Source Type: news
Fungal infections in mechanically ventilated patients with COVID-19 during the first wave: the French multicentre MYCOVID study
Cohort study (n=565) found 15% of mechanically ventilated patients with COVID-19 had proven or probable COVID-19-associated pulmonary aspergillosis (CAPA). Age>62yrs, treatment with dexamethasone and>14 days mechanical ventilation were associated with increased risk. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 30, 2021 Category: Consumer Health News Source Type: news
European CHMP recommend license extension of posaconazole (Noxafil) for fungal infections
The licence extension recommended for approval is for use in invasive aspergillosis in adults and children above 2 years age and 40kg weight with disease that is refractory to amphotericin B or itraconazole or in patients who are intolerant of these medicines. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 16, 2021 Category: Consumer Health News Source Type: news
Miltefosine Granted Orphan Drug Approval for Invasive Candidiasis Miltefosine Granted Orphan Drug Approval for Invasive Candidiasis
Invasive candidiasis is one of the most common fungal infections in patients with COVID-19.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 12, 2021 Category: Consumer Health News Tags: Infectious Diseases News Alert Source Type: news
Antibiotics? Handle with Care
The main drivers of antimicrobial resistance include the misuse and overuse of antimicrobials; lack of access to clean water, sanitation and hygiene for both humans and animals; poor infection and disease prevention and control in health-care facilities and farms; poor access to quality, affordable medicines, vaccines and diagnostics; lack of awareness and knowledge; and lack of enforcement of legislation. Credit: Bigstock.By Baher KamalMADRID, Nov 11 2021 (IPS) The following information is based on investigations and studies carried out by the World Health Organisation (WHO) and the Food and Agriculture Organisation (FAO)...
Source: IPS Inter Press Service - Health - November 11, 2021 Category: International Medicine & Public Health Authors: Baher Kamal Tags: Global Headlines Health Antibiotic Resistance Source Type: news
DR ELLIE CANNON: Could a burning rash down my arm be a side effect of the Covid jab?
DR ELLIE CANNON: When a rash affects one side of the body, most doctors consider shingles. Another common cause of a rash under the armpit is a fungal infection. (Source: the Mail online | Health)
Source: the Mail online | Health - October 30, 2021 Category: Consumer Health News Source Type: news
Fungal Infection Can Mimic Lung Cancer Metastases Fungal Infection Can Mimic Lung Cancer Metastases
A fungal infection typically seen in the lungs may have a variety of unusual clinical presentations elsewhere in the body.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 25, 2021 Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news
New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
Here ’s What Queer People With Vaginas Need To Know About Condoms And STI Protection
Although LGBTQ+ people like bisexual and lesbian women may not be at risk for pregnancy in a relationship, they can still contract STIs or develop fungal infections.
LGBTQ+ people with vaginas have several options to protect themselves. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - September 28, 2021 Category: Pharmaceuticals Authors: Laken Brooks, Contributor Tags: Healthcare /healthcare Innovation /innovation Source Type: news
Fungal Disease Awareness Week: fungal pathogen data and literature at NCBI
This post is in support of the CDC’s Fungal Disease Awareness Week — September 20-24, 2021. The impact of fungal diseases on human health has often been neglected, but increased association of fungal infections with severe illness and death during the COVID-19 pandemic has brought fungal diseases into the spotlight. According to the CDC, the … Continue reading Fungal Disease Awareness Week: fungal pathogen data and literature at NCBI → (Source: NCBI Insights)
Source: NCBI Insights - September 21, 2021 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Assembly COVID-19 Fungi PubMed RefSeq Source Type: news
How a scratch from a bramble almost cost woman her hand
Jackie Jackson, 60, from Hampshire was told a thorn caused a fungal infection in her hand which could have had devastating consequences without treatment. (Source: the Mail online | Health)
Source: the Mail online | Health - August 31, 2021 Category: Consumer Health News Source Type: news
Factors Linked to Development of Pediatric Psoriasis Identified
TUESDAY, Aug. 24, 2021 -- Atopic dermatitis, a family history of psoriasis, and skin viral and bacterial infection and fungal infections in early life are associated with pediatric psoriasis development, according to a study published in the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 24, 2021 Category: Pharmaceuticals Source Type: news
Program Update: The National Children ’s Cancer Society and Fosun...
The National Children’s Cancer Society (NCCS) secured a large quantity of Voriconazole, a drug used to treat fungal infections, for a hospital in Guatemala thanks to support from Fosun Pharma USA...(PRWeb August 20, 2021)Read the full story at https://www.prweb.com/releases/program_update_the_national_childrens_cancer_society_and_fosun_pharma_partner_to_help_patients_in_guatemala/prweb18133780.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - August 20, 2021 Category: Pharmaceuticals Source Type: news
Fungal Infections Associated With S. boulardii Probiotics Fungal Infections Associated With S. boulardii Probiotics
An association was found between some commonly used probiotics and life-threatening fungal infections.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - July 16, 2021 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news
How to get rid of ringworm - the 6 ways to stop ringworm from spreading
RINGWORM is a common fungal infection that can affect anyone and can be passed on. Here are five ways to stop ringworm from spreading. (Source: Daily Express - Health)
Source: Daily Express - Health - July 6, 2021 Category: Consumer Health News Source Type: news
