Clinical Center Clinicopathologic Grand Rounds: When Half Is Not Enough: STAT3 Haploinsufficiency and Fungal Infection of the Brain
Steven Holland, MD Michail Lionakis, MD, ScD Amy Hsu, PhD David Kleiner, MD, PhDFor more information go tohttps://clinicalcenter.nih.gov/about/news/grcurrent.htmlAir date: 9/6/2023 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - August 21, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

IIG Seminar
Michail Lionakis combines groundbreaking studies of murine candidiasis models with clinical and genomic insight from his stewardship of the world ’ s largest APECED patient cohort to generate radical, transformative discoveries of fungal infection at the intersection of colonization, invasion, and host defense. Dr. Lionakis has achieved many “ firsts ” , including identification of new AIRE and CARD9 mutations, redefinition of disease clinical spectra, and discovery of effective treatment regimens. He leverages his candidiasis mouse models to advance mechanistic insight, including how Card9 deficiency causes CNS-spec...
Source: Videocast - All Events - April 25, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Demystifying Medicine - Encephalitis and the Immune System
Demystifying Medicine Lecture Series Encephalitis, the inflammation of the brain, can be brought on by viral, bacterial and fungal infections, autoimmune diseases, and immunosuppression. Many diseases causing encephalitis are transmitted by mosquitos and ticks. As such, encephalitis is sadly pervasive, affecting more than 4 million people annually worldwide and causing upwards of 150,000 deaths. Symptoms range from mild headaches and nausea to debilitating seizures, hallucinations, and difficulty speaking and remembering. The patient volunteers at the NIH Clinical Center, many of whom are immunocompromised, are at a height...
Source: Videocast - All Events - February 6, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

NIH Director's Seminar: Of humans and mice: Fundamental mechanisms of tissue-specific antifungal immunity
NIH Director's Seminar Series Over the past few decades, fungal infections have emerged as major causes of morbidity and mortality in immunosuppressed patients despite the administration of antifungal therapy. This talk will highlight recent advances in our understanding of the cellular and molecular basis of protective host immunity against mucosal and invasive fungal infections. These insights have been gained via enrollment at the NIH Clinical Center of large cohorts of patients with inherited and acquired susceptibility to fungal disease and via corroborating immunological research in clinically relevant mouse models o...
Source: Videocast - All Events - June 5, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Of humans and mice: Fundamental mechanisms of tissue-specific antifungal immunity
NIH Director's Seminar Series Over the past few decades, fungal infections have emerged as major causes of morbidity and mortality in immunosuppressed patients despite the administration of antifungal therapy. This talk will highlight recent advances in our understanding of the cellular and molecular basis of protective host immunity against mucosal and invasive fungal infections. These insights have been gained via enrollment at the NIH Clinical Center of large cohorts of patients with inherited and acquired susceptibility to fungal disease and via corroborating immunological research in clinically relevant mouse models o...
Source: Videocast - All Events - June 3, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Type III interferon is a critical regulator of innate antifungal immunity
Immunology Interest Group Amariliz Rivera received her B.S from the University of Puerto Rico-Mayaguez campus and her PhD from Rutgers-Robert Wood Johnson Medical School. She did her postdoctoral training at MSKCC under the mentorship of Eric Pamer where she began the abiding theme of her research-achieving a better understanding of how the immune system fights fungal infections. After her training, she moved to Rutgers where she is Assistant Professor in the Department of Pediatrics and member of the Center of Immunity and Inflammation. Her work through the years has delineated fungus-specific CD4 T cell responses and mon...
Source: Videocast - All Events - October 16, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

John R. Wingard, MD - Invasive Fungal Infections in HCT Recipients: Case-Based Perspectives on Prevention and Treatment
Invasive Fungal Infections in HCT Recipients: Case-Based Perspectives on Prevention and Treatment (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - June 27, 2016 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

Dimitrios P. Kontoyiannis, MD, MS, ScD, FACP, FIDSA - Principles and Application of Antifungal Pharmacology: A Case-Based Approach to Optimizing Treatment Decisions in Individual Patients With Invasive Fungal Infections
Principles and Application of Antifungal Pharmacology: A Case-Based Approach to Optimizing Treatment Decisions in Individual Patients With Invasive Fungal Infections (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - December 11, 2015 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

Dimitrios P. Kontoyiannis, MD, MS, ScD, FACP, FIDSA - Minimizing the Burden of Invasive Fungal Infections: Practical Strategies to Improve Outcomes in the Inpatient Setting
Minimizing the Burden of Invasive Fungal Infections: Practical Strategies to Improve Outcomes in the Inpatient Setting (Source: Peerview CME/CE Video Podcast - Internal Medicine International)
Source: Peerview CME/CE Video Podcast - Internal Medicine International - May 8, 2015 Category: Internal Medicine Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

John R. Wingard, MD - Invasive Fungal Infections in Patients With Hematologic Malignancies: Expert Perspectives on Current and Future Approaches to Prevention and Treatment
Invasive Fungal Infections in Patients With Hematologic Malignancies: Expert Perspectives on Current and Future Approaches to Prevention and Treatment (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - September 22, 2014 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video