Fatal fluorosilicic acid exposure after a motor vehicle crash: a case report - Yorke JA, McNaughton-Filion L, Herath JC.
Fluorosilicic acid (FSA) is a corrosive liquid used in manufacturing and other processes. High-level exposures to FSA cause fluoride toxicity resulting in profound hypocalcemia, potentially leading to sudden death. Prompt recognition of exposure risk allow... (Source: SafetyLit)
Source: SafetyLit - August 13, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

A short de novo synthesis of nucleoside analogs
We present a process for rapidly constructing nucleoside analogs from simple achiral materials. Using only proline catalysis, heteroaryl-substituted acetaldehydes are fluorinated and then directly engaged in enantioselective aldol reactions in a one-pot reaction. A subsequent intramolecular fluoride displacement reaction provides a functionalized nucleoside analog. The versatility of this process is highlighted in multigram syntheses of d- or l-nucleoside analogs, locked nucleic acids, iminonucleosides, and C2'- and C4'-modified nucleoside analogs. This de novo synthesis creates opportunities for the preparation of diversi...
Source: ScienceNOW - August 5, 2020 Category: Science Authors: Meanwell, M., Silverman, S. M., Lehmann, J., Adluri, B., Wang, Y., Cohen, R., Campeau, L.-C., Britton, R. Tags: Chemistry reports Source Type: news

Skeletal fluorosis: an unusual manifestation of computer cleaner inhalant abuse - Liane BJ, Chow A, Kline D.
Skeletal fluorosis is a metabolic bone disease caused by accumulation of fluoride and is generally associated with chronic exposure to fluoride-contaminated groundwater, a phenomenon endemic to developing countries. Whereas elevated water fluoride concentr... (Source: SafetyLit)
Source: SafetyLit - July 14, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Effects of desensitizing products on the reduction of pain sensitivity caused by in-office tooth bleaching: a 24-week follow-up
Conclusion Our results indicate that adding NF/S, NA/S, NF/AC, and NA/AC desensitizers to tooth bleaching protocols reduces pain sensitivity without affecting its effectiveness. (Source: Dental Technology Blog)
Source: Dental Technology Blog - July 2, 2020 Category: Dentistry Source Type: news

Simple oral health steps help improve elite athletes' performance
(University College London) Elite athletes who adopted simple oral health measures, such as using high fluoride toothpaste and cleaning between their teeth, reported significantly reduced negative effects on performance related to poor oral health, finds a study led by UCL. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 18, 2020 Category: International Medicine & Public Health Source Type: news

Comparison of Fluoride Release in Conventional Glass-Ionomer Cements with a New Mechanical Mixing Cement
Conclusions: A mechanical mixing was the material with the more constant fluoride release and after recharge showed the highest fluoride release which make it an important benefit for clinicians. (Source: Dental Technology Blog)
Source: Dental Technology Blog - May 5, 2020 Category: Dentistry Source Type: news

How to intervene in the caries process: proximal caries in adolescents and adults —a systematic review and meta-analysis
ConclusionsProximal caries lesions can be managed successfully with non-operative, micro-invasive and restorative treatment according to lesion stage and caries activity.Clinical relevanceProximal caries treatment options like non-operative, micro-invasive and restorative care should be considered individually. (Source: Dental Technology Blog)
Source: Dental Technology Blog - April 23, 2020 Category: Dentistry Source Type: news

Comparison of two caries prevention programs among Thai kindergarten: a randomized controlled trial
ConclusionsThe negligible difference in caries increment between the HRI and HRB groups implies that intensified prevention produced minimal additional benefit. Offering all children only basic prevention could have obtained virtually the same preventive effect with substantially less effort and lower cost. (Source: Dental Technology Blog)
Source: Dental Technology Blog - April 22, 2020 Category: Dentistry Source Type: news

Oral Science Expands to the U.S. Market
Dental Health Company Oral Science Brings Its Best-Selling Oral Hygiene Products to the United StatesFORT LAUDERDALE, Fla., March 31, 2020 /PRNewswire/ -- Canadian dental health company, Oral Science is expanding its reach to the United States market. Known for producing high-quality oral hygiene products, Oral Science partners with dental professionals to supply a variety of rinses, toothpastes, and specialty items.Founded in 2004, Oral Science is known for its innovation in the field of dental health, making waves as a leader in both treatment and prevention of oral health conditions. Oral Scienc...
Source: Dental Technology Blog - April 7, 2020 Category: Dentistry Source Type: news

What Causes Tachycardia?
Discussion Tachycardia is a rapid heart rate that is above normal for age and level of exertion. Tachycardia is common, particularly sinus tachycardia due to normally encountered circumstances such as pain, fever or exercise. It is usually a normal physiologic process but sustained tachycardia often indicates a potentially abnormal underlying cause. Sinus tachycardia has a rapid heart rate with normal P waves and P-R intervals and variations from moment to moment and respiration. Generally it is not over 200 beats/minute. Vagal stimulation can slow the heart rate; this is a gradual slowing, not an abrupt slowing seen in ...
Source: PediatricEducation.org - March 23, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Experts Question Evidence Linking Fluoride to Lower IQ Experts Question Evidence Linking Fluoride to Lower IQ
A committee of experts that conducted a systematic review of the literature on neurodevelopmental and cognitive effects of fluoride exposure raises a number of concerns.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - March 6, 2020 Category: Psychiatry Tags: Psychiatry News Source Type: news

National Academies Completes Peer Review of NTP Monograph
A National Academies committee was tasked with reviewing the National Toxicology Program’s draft monograph Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects. The committee focused on evaluating whether evidence as presented in the monograph supported NTP’s conclusions. The committee did not conduct its own independent evaluation of the evidence or conduct a data audit. Read More (Source: News from the National Academies)
Source: News from the National Academies - March 5, 2020 Category: Science Source Type: news

National Academies Completes Review of National Toxicology Program ’s Draft Monograph on Fluoride and Neurodevelopmental and Cognitive Effects
Today the National Academies of Sciences, Engineering, and Medicine released its review of the National Toxicology Program ’s (NTP) draft monograph Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects. (Source: News from the National Academies)
Source: News from the National Academies - March 5, 2020 Category: Science Source Type: news

Certain Fluoride is Unsafe for Children's Developing Brains
Developmental neurotoxicity is a serious risk associated with elevated fluoride exposure, whether due to community water fluoridation, natural fluoride release from soil minerals, or tea consumption (Source: Disabled World)
Source: Disabled World - March 2, 2020 Category: Disability Tags: Children and Youth Source Type: news