Electroanalytical application of a boron-doped diamond electrode: improving the simultaneous voltammetric determination of amlodipine and valsartan in urine and combined dosage forms
Publication date: Available online 27 November 2014 Source:Journal of Electroanalytical Chemistry Author(s): Guilherme Roberto Mansano , Ana Paula Pires Eisele , Luiz Henrique Dall’Antonia , Sabrina Afonso , Elen Romão Sartori A new voltammetric method was developed for simultaneous determination of amlodipine (AML) and valsartan (VAL) in synthetic urine and combined pharmaceutical formulations. The anodic peak potentials of AML and VAL oxidation at a cathodically pretreated boron-doped diamond electrode were found to be 0.791 V and 1.37 V (vs. Ag/AgCl (3.0 mol L−1 KCl)), respectively, by cyclic voltammetry, ...
Source: Journal of Electroanalytical Chemistry - November 30, 2014 Category: Chemistry Source Type: research
Endocan, a novel marker of endothelial dysfunction in patients with essential hypertension: Comparative effects of amlodipine and valsartan
Blood Pressure, Ahead of Print. (Source: Blood Pressure)
Source: Blood Pressure - November 13, 2014 Category: Hematology Tags: article Source Type: research
Health Care Utilization and Cost Comparison Between Adherent Hypertension Patients Treated by Single Exforge HCT and Amlodipine/Valsartan/Hydrochlorothiazide Free Combination
This study investigated if Exforge HCT is associated with reduced health care utilization and costs during the 12 months follow up period in adult hypertensive (HTN) patients adherent to treatment. (Source: Value in Health)
Source: Value in Health - November 1, 2014 Category: Global & Universal Authors: W Chen, Z Wei, SH Ong, G Machnicki, K Kristijan Source Type: research
Azilsartan, Aliskiren, and Combination Antihypertensives Utilizing Renin–Angiotensin–Aldosterone System Antagonists
Health care providers managing hypertension (HTN) have a large selection of pharmacologic agents to choose from, including several different classes of drugs and many similar drugs within each class. Antagonism of the renin–angiotensin–aldosterone system has been shown to be very effective for HTN, especially in patients with cardiovascular disease, diabetes, and heart failure. Within this group, there have been 2 new agents recently introduced to the US market and approved by the Food and Drug Administration. It is important for the HTN specialist to be familiar with the merits of these 2 drugs: the angiotensin recept...
Source: American Journal of Therapeutics - September 1, 2014 Category: Drugs & Pharmacology Tags: Therapeutic Review Source Type: research
Real-life effectiveness, safety, and tolerability of amlodipine/valsartan or amlodipine/valsartan/hydrochlorothiazide single-pill combination in patients with hypertension from Pakistan
Conclusions:
Aml/Val with or without HCTZ in a SPC was effective and well-tolerated for BP reduction in this cohort of patients with hypertension from Pakistan. (Source: Therapeutic Advances in Cardiovascular Disease)
Source: Therapeutic Advances in Cardiovascular Disease - March 18, 2014 Category: Cardiology Authors: Khan, W., Moin, N., Iktidar, S., Sakrani, J., Abid, R., Afzal, J., Maheshwary, N., Kumar, K., Siddiqi, A., Qadir, M. Tags: Original Research Source Type: research
Age and the effectiveness of anti-hypertensive therapy on improvement in diastolic function
Conclusions: In our sample of individuals with hypertension and diastolic dysfunction, older compared to younger adults experienced less improvement in diastolic function in response to similar reductions in SBP. (Source: Journal of Hypertension)
Source: Journal of Hypertension - December 17, 2013 Category: Cardiology Tags: ORIGINAL PAPERS: Therapeutic aspects Source Type: research
The Comparative Effects of Valsartan and Amlodipine on vWf Levels and N/L Ratio in Patients with Newly Diagnosed Hypertension.
Abstract
High levels of circulating Von Willebrand factor (vWf) and increased neutrophil to lymphocyte (N/L) ratio may reflect vascular inflammation in hypertensive patients. In present study, we aimed to investigate the effects of valsartan as an angiotensin II receptor antagonist and amlodipine as a calcium channel blocker on the vWf levels and N/L ratio in patients with essential hypertension. Patients were randomized to one of the following intervention protocols: calcium channel blocker (amlodipine, 5-10 mg/day) as group A (n = 20 mean age = 51.85 ± 11.32 y) and angiotensine II receptor blocke...
Source: Clinical and Experimental Hypertension - January 4, 2013 Category: Cardiology Authors: Karaman M, Balta S, Ay SA, Cakar M, Naharci I, Demirkol S, Celik T, Arslan Z, Kurt O, Kocak N, Sarlak H, Demirbas S, Bulucu F, Bozoglu E Tags: Clin Exp Hypertens Source Type: research
