Association Between Z Drugs Use and Risk of Cognitive Impairment in Middle-Aged and Older Patients With Chronic Insomnia
Conclusion: BZD exposure density was an independent risk factor of cognitive impairment in middle-aged and older patients with chronic insomnia, but no correlation was found between Z drug use and cognitive impairment. Moreover, the use of Z drugs seemed to be associated with protection for attention. The use for prescription of BZDs, in this case, should be avoided or limited to low doses. Due to the addiction and tolerance, Z drugs should also be prescribed with great caution in middle-aged and elderly patients. (Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - December 9, 2021 Category: Neuroscience Source Type: research

Standardization of Hypnotic Agents for Prevention of Falls: A Pharmacoeconomic Study
In this study, the standardization of insomnia treatment was evaluated by pharmacoeconomics. The costs of the hypnotic agents was considered, as was the cost of examination/treatment following falls. Effectiveness was evaluated as the incidence of falls within 24 hours of taking hypnotic agents. This analysis took the public healthcare payer's perspective. Propensity score matching based on patient background, showed that, per hospitalization the medicine costs of the recommended group increased by 1,020 yen, however, the examination/treatment costs following falls decreased by 487 yen when compared with the non-recommende...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 1, 2021 Category: Drugs & Pharmacology Authors: Atsuyuki Saisyo Miwako Takasago Kazuki Wakabayashi Mari Akiyama Kyoji Kouda Akihisa Takasaki Kazuto Matsunaga Haku Ishida Takashi Kitahara Source Type: research

Standardization of Hypnotic Agents for Prevention of Falls: A Pharmacoeconomic Study
In this study, the standardization of insomnia treatment was evaluated by pharmacoeconomics. The costs of the hypnotic agents was considered, as was the cost of examination/treatment following falls. Effectiveness was evaluated as the incidence of falls within 24 hours of taking hypnotic agents. This analysis took the public healthcare payer's perspective. Propensity score matching based on patient background, showed that, per hospitalization the medicine costs of the recommended group increased by 1,020 yen, however, the examination/treatment costs following falls decreased by 487 yen when compared with the non-recommende...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 1, 2021 Category: Drugs & Pharmacology Authors: Atsuyuki Saisyo Miwako Takasago Kazuki Wakabayashi Mari Akiyama Kyoji Kouda Akihisa Takasaki Kazuto Matsunaga Haku Ishida Takashi Kitahara Source Type: research

Standardization of Hypnotic Agents for Prevention of Falls: A Pharmacoeconomic Study
In this study, the standardization of insomnia treatment was evaluated by pharmacoeconomics. The costs of the hypnotic agents was considered, as was the cost of examination/treatment following falls. Effectiveness was evaluated as the incidence of falls within 24 hours of taking hypnotic agents. This analysis took the public healthcare payer's perspective. Propensity score matching based on patient background, showed that, per hospitalization the medicine costs of the recommended group increased by 1,020 yen, however, the examination/treatment costs following falls decreased by 487 yen when compared with the non-recommende...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 1, 2021 Category: Drugs & Pharmacology Authors: Atsuyuki Saisyo Miwako Takasago Kazuki Wakabayashi Mari Akiyama Kyoji Kouda Akihisa Takasaki Kazuto Matsunaga Haku Ishida Takashi Kitahara Source Type: research

Standardization of Hypnotic Agents for Prevention of Falls: A Pharmacoeconomic Study
In this study, the standardization of insomnia treatment was evaluated by pharmacoeconomics. The costs of the hypnotic agents was considered, as was the cost of examination/treatment following falls. Effectiveness was evaluated as the incidence of falls within 24 hours of taking hypnotic agents. This analysis took the public healthcare payer's perspective. Propensity score matching based on patient background, showed that, per hospitalization the medicine costs of the recommended group increased by 1,020 yen, however, the examination/treatment costs following falls decreased by 487 yen when compared with the non-recommende...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 1, 2021 Category: Drugs & Pharmacology Authors: Atsuyuki Saisyo Miwako Takasago Kazuki Wakabayashi Mari Akiyama Kyoji Kouda Akihisa Takasaki Kazuto Matsunaga Haku Ishida Takashi Kitahara Source Type: research

Standardization of Hypnotic Agents for Prevention of Falls: A Pharmacoeconomic Study
In this study, the standardization of insomnia treatment was evaluated by pharmacoeconomics. The costs of the hypnotic agents was considered, as was the cost of examination/treatment following falls. Effectiveness was evaluated as the incidence of falls within 24 hours of taking hypnotic agents. This analysis took the public healthcare payer's perspective. Propensity score matching based on patient background, showed that, per hospitalization the medicine costs of the recommended group increased by 1,020 yen, however, the examination/treatment costs following falls decreased by 487 yen when compared with the non-recommende...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 1, 2021 Category: Drugs & Pharmacology Authors: Atsuyuki Saisyo Miwako Takasago Kazuki Wakabayashi Mari Akiyama Kyoji Kouda Akihisa Takasaki Kazuto Matsunaga Haku Ishida Takashi Kitahara Source Type: research

Standardization of Hypnotic Agents for Prevention of Falls: A Pharmacoeconomic Study
In this study, the standardization of insomnia treatment was evaluated by pharmacoeconomics. The costs of the hypnotic agents was considered, as was the cost of examination/treatment following falls. Effectiveness was evaluated as the incidence of falls within 24 hours of taking hypnotic agents. This analysis took the public healthcare payer's perspective. Propensity score matching based on patient background, showed that, per hospitalization the medicine costs of the recommended group increased by 1,020 yen, however, the examination/treatment costs following falls decreased by 487 yen when compared with the non-recommende...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 1, 2021 Category: Drugs & Pharmacology Authors: Atsuyuki Saisyo Miwako Takasago Kazuki Wakabayashi Mari Akiyama Kyoji Kouda Akihisa Takasaki Kazuto Matsunaga Haku Ishida Takashi Kitahara Source Type: research

Standardization of Hypnotic Agents for Prevention of Falls: A Pharmacoeconomic Study
In this study, the standardization of insomnia treatment was evaluated by pharmacoeconomics. The costs of the hypnotic agents was considered, as was the cost of examination/treatment following falls. Effectiveness was evaluated as the incidence of falls within 24 hours of taking hypnotic agents. This analysis took the public healthcare payer's perspective. Propensity score matching based on patient background, showed that, per hospitalization the medicine costs of the recommended group increased by 1,020 yen, however, the examination/treatment costs following falls decreased by 487 yen when compared with the non-recommende...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 1, 2021 Category: Drugs & Pharmacology Authors: Atsuyuki Saisyo Miwako Takasago Kazuki Wakabayashi Mari Akiyama Kyoji Kouda Akihisa Takasaki Kazuto Matsunaga Haku Ishida Takashi Kitahara Source Type: research

Standardization of Hypnotic Agents for Prevention of Falls: A Pharmacoeconomic Study
In this study, the standardization of insomnia treatment was evaluated by pharmacoeconomics. The costs of the hypnotic agents was considered, as was the cost of examination/treatment following falls. Effectiveness was evaluated as the incidence of falls within 24 hours of taking hypnotic agents. This analysis took the public healthcare payer's perspective. Propensity score matching based on patient background, showed that, per hospitalization the medicine costs of the recommended group increased by 1,020 yen, however, the examination/treatment costs following falls decreased by 487 yen when compared with the non-recommende...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 1, 2021 Category: Drugs & Pharmacology Authors: Atsuyuki Saisyo Miwako Takasago Kazuki Wakabayashi Mari Akiyama Kyoji Kouda Akihisa Takasaki Kazuto Matsunaga Haku Ishida Takashi Kitahara Source Type: research

Standardization of Hypnotic Agents for Prevention of Falls: A Pharmacoeconomic Study
In this study, the standardization of insomnia treatment was evaluated by pharmacoeconomics. The costs of the hypnotic agents was considered, as was the cost of examination/treatment following falls. Effectiveness was evaluated as the incidence of falls within 24 hours of taking hypnotic agents. This analysis took the public healthcare payer's perspective. Propensity score matching based on patient background, showed that, per hospitalization the medicine costs of the recommended group increased by 1,020 yen, however, the examination/treatment costs following falls decreased by 487 yen when compared with the non-recommende...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 1, 2021 Category: Drugs & Pharmacology Authors: Atsuyuki Saisyo Miwako Takasago Kazuki Wakabayashi Mari Akiyama Kyoji Kouda Akihisa Takasaki Kazuto Matsunaga Haku Ishida Takashi Kitahara Source Type: research

Standardization of Hypnotic Agents for Prevention of Falls: A Pharmacoeconomic Study
In this study, the standardization of insomnia treatment was evaluated by pharmacoeconomics. The costs of the hypnotic agents was considered, as was the cost of examination/treatment following falls. Effectiveness was evaluated as the incidence of falls within 24 hours of taking hypnotic agents. This analysis took the public healthcare payer's perspective. Propensity score matching based on patient background, showed that, per hospitalization the medicine costs of the recommended group increased by 1,020 yen, however, the examination/treatment costs following falls decreased by 487 yen when compared with the non-recommende...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 1, 2021 Category: Drugs & Pharmacology Authors: Atsuyuki Saisyo Miwako Takasago Kazuki Wakabayashi Mari Akiyama Kyoji Kouda Akihisa Takasaki Kazuto Matsunaga Haku Ishida Takashi Kitahara Source Type: research

Standardization of Hypnotic Agents for Prevention of Falls: A Pharmacoeconomic Study
In this study, the standardization of insomnia treatment was evaluated by pharmacoeconomics. The costs of the hypnotic agents was considered, as was the cost of examination/treatment following falls. Effectiveness was evaluated as the incidence of falls within 24 hours of taking hypnotic agents. This analysis took the public healthcare payer's perspective. Propensity score matching based on patient background, showed that, per hospitalization the medicine costs of the recommended group increased by 1,020 yen, however, the examination/treatment costs following falls decreased by 487 yen when compared with the non-recommende...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 1, 2021 Category: Drugs & Pharmacology Authors: Atsuyuki Saisyo Miwako Takasago Kazuki Wakabayashi Mari Akiyama Kyoji Kouda Akihisa Takasaki Kazuto Matsunaga Haku Ishida Takashi Kitahara Source Type: research

Standardization of Hypnotic Agents for Prevention of Falls: A Pharmacoeconomic Study
In this study, the standardization of insomnia treatment was evaluated by pharmacoeconomics. The costs of the hypnotic agents was considered, as was the cost of examination/treatment following falls. Effectiveness was evaluated as the incidence of falls within 24 hours of taking hypnotic agents. This analysis took the public healthcare payer's perspective. Propensity score matching based on patient background, showed that, per hospitalization the medicine costs of the recommended group increased by 1,020 yen, however, the examination/treatment costs following falls decreased by 487 yen when compared with the non-recommende...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 1, 2021 Category: Drugs & Pharmacology Authors: Atsuyuki Saisyo Miwako Takasago Kazuki Wakabayashi Mari Akiyama Kyoji Kouda Akihisa Takasaki Kazuto Matsunaga Haku Ishida Takashi Kitahara Source Type: research

Standardization of Hypnotic Agents for Prevention of Falls: A Pharmacoeconomic Study
In this study, the standardization of insomnia treatment was evaluated by pharmacoeconomics. The costs of the hypnotic agents was considered, as was the cost of examination/treatment following falls. Effectiveness was evaluated as the incidence of falls within 24 hours of taking hypnotic agents. This analysis took the public healthcare payer's perspective. Propensity score matching based on patient background, showed that, per hospitalization the medicine costs of the recommended group increased by 1,020 yen, however, the examination/treatment costs following falls decreased by 487 yen when compared with the non-recommende...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 1, 2021 Category: Drugs & Pharmacology Authors: Atsuyuki Saisyo Miwako Takasago Kazuki Wakabayashi Mari Akiyama Kyoji Kouda Akihisa Takasaki Kazuto Matsunaga Haku Ishida Takashi Kitahara Source Type: research

Standardization of Hypnotic Agents for Prevention of Falls: A Pharmacoeconomic Study
In this study, the standardization of insomnia treatment was evaluated by pharmacoeconomics. The costs of the hypnotic agents was considered, as was the cost of examination/treatment following falls. Effectiveness was evaluated as the incidence of falls within 24 hours of taking hypnotic agents. This analysis took the public healthcare payer's perspective. Propensity score matching based on patient background, showed that, per hospitalization the medicine costs of the recommended group increased by 1,020 yen, however, the examination/treatment costs following falls decreased by 487 yen when compared with the non-recommende...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 1, 2021 Category: Drugs & Pharmacology Authors: Atsuyuki Saisyo Miwako Takasago Kazuki Wakabayashi Mari Akiyama Kyoji Kouda Akihisa Takasaki Kazuto Matsunaga Haku Ishida Takashi Kitahara Source Type: research