Harder, better, faster, stronger? Retrospective chart review of adverse events of interactions between adaptogens and antidepressant drugs
Conclusion: Clinicians should monitor the adverse events associated with the concomitant use of adaptogens and antidepressant drugs in patients with mental disorders. Aggregation of side effects and pharmacokinetic interactions (inhibition of CYP and p-glycoprotein) between those medicines may result in clinically significant adverse events. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - September 27, 2023 Category: Drugs & Pharmacology Source Type: research
Pale man with recurrent epistaxis
Clinical introduction A 78-year-old man with a recent history of general fatigue, exertional dyspnoea and recurrent epistaxis presented to our ED. His medical history was mild hyperlipidaemia. He denied chest pain, dyspnoea, leg swelling, drug abuse or facial trauma. His vital signs were stable. Physical findings also revealed pale skin and conjunctival pallor. His oral exam is shown in figure 1. Laboratory examination showed a haemoglobin of 4.8 g/dL (reference range 13.7–16.8 g/dL) and decreased mean corpuscular volume of 74.1 fL (reference range 83.6–98.2 fL). Question What is the most likely cause? Maffucci...
Source: Emergency Medicine Journal - September 27, 2023 Category: Emergency Medicine Authors: Matsuura, H., Imajo, K. Tags: EMJ Image Challenge Source Type: research
Angioleiomyoma of the Sinonasal Tract: A Systematic Review of an Uncommon Clinicopathological Entity
Conclusion To our knowledge, only 87 cases of sinonasal-tract angioleiomyoma have been previously described. The results of the present review seem to confirm the rarity and the benign nature of this neoplasm, and they seem to confirm the necessity to improve the available data about sinonasal-tract angioleiomyoma. [...] Thieme Revinter Publicações Ltda. Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, BrazilArticle in Thieme eJournals: Table of contents | Abstract | open access Full text (Source: International Archives of Otorhinolaryngology)
Source: International Archives of Otorhinolaryngology - September 26, 2023 Category: ENT & OMF Authors: Velletrani, Gianluca Maurizi, Riccardo De Padova, Alessandro Di Girolamo, Stefano Tags: Systematic Review Source Type: research
Nasal Respiratory Epithelial Adenomatoid Hamartoma: Three Case Reports and Review of the Literature
Ear Nose Throat J. 2023 Sep 25:1455613231198996. doi: 10.1177/01455613231198996. Online ahead of print.ABSTRACTHamartomas, as non-true tumors, are commonly found in the lungs, digestive tract, and kidneys, and there are few clinical reports on nasal cases. Nasal histiocytosis accompanied by lymphatic lesions is a common feature of nasal hamartoma. Three patients with nasal cavity hamartoma were treated in our department, including 1 male and 2 females, with nasal obstruction or epistaxis. The imaging (computed tomography, magnetic resonance imaging) of 2 patients showed a soft tissue mass in the nasal cavity and no erosion...
Source: Ear, Nose and Throat Journal - September 25, 2023 Category: ENT & OMF Authors: Jiangxue Liao Xuge Zhang Wei Xu Fei Li Gang Qin Source Type: research
Nasal Respiratory Epithelial Adenomatoid Hamartoma: Three Case Reports and Review of the Literature
Ear Nose Throat J. 2023 Sep 25:1455613231198996. doi: 10.1177/01455613231198996. Online ahead of print.ABSTRACTHamartomas, as non-true tumors, are commonly found in the lungs, digestive tract, and kidneys, and there are few clinical reports on nasal cases. Nasal histiocytosis accompanied by lymphatic lesions is a common feature of nasal hamartoma. Three patients with nasal cavity hamartoma were treated in our department, including 1 male and 2 females, with nasal obstruction or epistaxis. The imaging (computed tomography, magnetic resonance imaging) of 2 patients showed a soft tissue mass in the nasal cavity and no erosion...
Source: Ear, Nose and Throat Journal - September 25, 2023 Category: ENT & OMF Authors: Jiangxue Liao Xuge Zhang Wei Xu Fei Li Gang Qin Source Type: research
Pituitary surgery outcome in patients 75 years and older: a retrospective study
ConclusionsSurgery beyond the age of 75, mainly relying on an endoscopic endonasal transsellar approach, is effective and safe, provided that patients are managed in tertiary centers. (Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - September 22, 2023 Category: Neurosurgery Source Type: research
Giant Internal Carotid Artery Aneurysm of the Cavernous Segment
Acta Neurol Taiwan. 2023 Dec 30;32(4):226-227.ABSTRACTA 70-year-old woman with a history of hypertension developed acute onset of severe tightness headache accompanied by vomiting. Patient reported having right diplopia and occasional and temporary right peripheral facial paralysis for two weeks. Neurological examination revealed only a right squint. Cerebral multi-detector computed tomographic angiography (MD-CTA) and Magnetic Resonance Imaging (MRI) revealed a giant right internal carotid aneurysm (2.7 cm) at the cavenous segment (Figure 1A, 1B). No abnormalities were noted in subarachnoid spaces and white - grey matter....
Source: Acta Neurologica Taiwanica - September 19, 2023 Category: Neurology Authors: Umberto G Rossi Alessandro Valdata Antonio Castaldi Source Type: research
