Smart Textiles Recognize Body Movements
Engineers at MIT have developed smart textiles that can detect and recognize body movements. The garments fit snugly, and contain a network of pressure sensors that can detect movement, and in conjunction with machine learning approaches, the technology can learn to recognize specific movements in wearers. The fabric contains conductive yarns and piezoresistive components that change their resistance when pressure is applied. To reduce the data noise that occurs when the fabrics jostle together during movement, the researchers used thermoforming fabrics that help to stick the knitted layers together. The garments could be ...
Source: Medgadget - July 19, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Materials Medicine Rehab mit MITnews Source Type: blogs
Pneumatic Prosthesis to Reduce Pressure and Irritation for Amputees
At the University of Waterloo in Canada, researchers have developed a microfluidic-based pneumatic system that adjusts the pressure within the socket of a lower limb prosthesis. The aim is to achieve the ideal pressure and adjust the fit of the prosthesis to compensate for changes in the size of the residual limb because of swelling. Current lower limb prostheses require users to change silicone and fabric liners manually to adjust the fit of their prosthetic device. This is suboptimal, particularly in patients with diabetes who may have limited feeling in their residual limb, leading to chafing and ulceration. This new de...
Source: Medgadget - July 8, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Rehab prosthetics UWaterloo Source Type: blogs
Self-Regulating Footwear for Diabetic Foot Issues
Researchers at the Indian Institute of Science created footwear that can self-regulate the pressure distribution when a person walks, helping to avoid pain and friction that can lead to issues for people with diabetes. Patients with diabetes can have an abnormal gait, sometimes because of pain or numbness in the extremities, potentially leading to complications such as foot ulcers when shoes rub or otherwise damage feet. These new shoes contain several arches that snap back into position when pressure that exceeds a certain level is applied, helping to distribute the pressure evenly and avoiding excessive pressure and fric...
Source: Medgadget - June 16, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Materials Medicine Neurology Rehab Sports Medicine Source Type: blogs
Presenting Wound Care Research at the American Geriatrics Society Annual Meeting
Emily Samuels MD, Stephanie Le MD, and Jeffrey M. Levine MD presenting at the AGS Annual Meeting in Orlando, FL
It was my great pleasure to present wound care research at the annual meeting of the American Geriatrics Society (AGS) that took place in Orlando, Florida. Our research was entitled Pressure Injuries and Wound Care: A Lost Geriatric Syndrome. First author was Emily Samuels MD, a geriatrician-in-training who will soon become attending physician with the Department of Geriatrics and Palliative Care at the Mount Sinai Medical Center. Co-authors included Stephanie Le MD, Clinical Assistant Professor and Assista...
Source: Jeffrey M. Levine MD | Geriatric Specialist | Wound Care | Pressure Ulcers - May 15, 2022 Category: Geriatrics Authors: Jeffrey M Levine Tags: An Aging World Featured Medical Articles Geriatric Medicine Pressure Injuries & Wound Care Publications bedsore bedsores decubiti decubitus ulcer end-of-life care eschar geriatrics Healthcare Quality Improving Medical Care medi Source Type: blogs
COVID-Related Skin Injuries
Thankfully the worst of the COVID-19 pandemic is over, but there is no doubt that the public health crisis brought new challenges to the wound care world. There has been profound impact upon caregivers and patients, including the epidemiology of skin lesions such as pressure injuries. The reverberations of the pandemic are still lingering, and this post will call attention to major concerns.
Impact of COVID-19 on Pressure Injury Epidemiology
The impact of SARS-CoV-2 on the occurrence of pressure injuries is substantial. Patients with severe respiratory disease and extended ICU admissions while on life support such as v...
Source: Jeffrey M. Levine MD | Geriatric Specialist | Wound Care | Pressure Ulcers - May 3, 2022 Category: Geriatrics Authors: Jeffrey M Levine Tags: Featured Medical Articles Geriatric Medicine Pressure Injuries & Wound Care bedsores coronavirus COVID COVID-19 decubiti decubitus ulcer Healthcare Quality Improving Medical Care pandemic pressure sore pressure sores pressure u Source Type: blogs
Fight Aging! Newsletter, October 25th 2021
This study confirmed that the PSI could be a quantitative index of vascular aging and has potential for use in inferring arterial stiffness with an advantage over the rAIx.
A Profile of Michael Greve and the Segment of the Longevity Industry that He Supports
https://www.fightaging.org/archives/2021/10/a-profile-of-michael-greve-and-the-segment-of-the-longevity-industry-that-he-supports/
Would that the popular media produced more popular science articles about the longevity industry like this one. It is not just a profile of someone trying to make a difference in the world by advancing the state of medic...
Source: Fight Aging! - October 24, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Reduced Skin Stem Cell Motility in the Age-Related Loss of Regenerative Capacity
Old age brings with it a much reduced capacity for healing of skin injuries. Researchers here delve into the details, identifying factors that negatively influence the ability of keratinocyte stem cells to migrate. This offers the potential to override the reaction of these stem cells to age-related changes in the signaling environment. This sort of compensatory approach does nothing to address the underlying damage of aging that causes such changes in signaling. As a class of approach, compensation will never be as good as repair of damage, but compensatory signaling can in some cases still be beneficial enough to be wort...
Source: Fight Aging! - October 22, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Microneedle Patch Delivers Oxygen to Chronic Wounds
A team of scientists at Purdue University created a microneedle patch that can deliver oxygen and bactericidal agents to chronic wounds.
The bacterial biofilms that form over non-healing wounds, such as foot ulcers, are a formidable barrier to successful treatment. Such wounds are typically hypoxic and the bacteria within them are shielded from antibiotics within the biofilm structure. This latest technology is designed to non-invasively penetrate such biofilms to deliver calcium peroxide, resulting in bactericidal action and oxygen generation within the wound.
Chronic wounds are a significant source of suffering an...
Source: Medgadget - September 28, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Materials Medicine Surgery purdue Source Type: blogs
Science Snippet: Brush Up on Biofilms
A biofilm is a highly organized community of microorganisms that develops naturally on certain surfaces. Typically, biofilms are made up of microbes and an extracellular matrix that they produce. This matrix can include polysaccharides (chains of sugars), proteins, lipids, DNA, and other molecules. The matrix gives the biofilm structure and helps it stick to a surface.
Formation of a biofilm often involves a process called quorum sensing. In this process, microbes detect when they reach a certain population density and change their behavior in ways that help them function as a community.
Biofilms are common and h...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - September 22, 2021 Category: Research Authors: Chrissa Chverchko Tags: Cells Injury and Illness Bacteria Biofilms Microbes Source Type: blogs
Cardiology MCQs
Which of the following is NOT a drug used for metabolic modulation in heart failure?
Trimetazidine
Ranolazine
Perhexiline
Sacubitril-valsartan
Correct answer: 4. Sacubitril-valsartan
Sacubitril-valsartan is an angiotensin receptor-neprilysin inhibitor (ARNI). Trimetazidine is a 3-ketoacyl coenzyme A thiolase inhibitor, while ranolazine inhibits the late sodium current. Perhexiline inhibits carnitine palmitoyl transferase. Latter three are metabolic modulators while sacubitril-valsartan is a hemodynamic modulator in heart failure [Ashrafian H, Neubauer S. Metabolic modulation in heart failure: high time for a definitive ...
Source: Cardiophile MD - July 4, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
Placental Allografts for Diabetic Foot Ulcers: Interview with Tim Wright, CEO of MiMedx
MiMedx, a medtech company based in Georgia, has developed EpiFix, an off-the-shelf allograft system for the treatment of diabetic foot ulcers. The grafts are made using donated human placental tissues that are obtained from consenting mothers during caesarean section procedures. The tissues then undergo a proprietary processing procedure to clean them and eventually produce a dehydrated graft that can be stored at room temperature long term.
Diabetic foot ulcers are relatively common in patients with diabetes, presenting in as many as 15% of such patients. These wounds are stubborn and typically resistant to treatment, ...
Source: Medgadget - February 18, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Medicine Surgery Vascular Surgery Source Type: blogs
Fight Aging! Newsletter, February 1st 2021
In this study, we characterize age-related phenotypes of human hematopoietic stem cells (HSCs). We report increased frequencies of HSC, hematopoetic progenitor cells (HPC), and lineage negative cells in the elderly but a decreased frequency of multi-lymphoid progenitors. Aged human HSCs further exhibited a delay in initiating division ex vivo though without changes in their division kinetics. The activity of the small RhoGTPase Cdc42 was elevated in aged human hematopoietic cells and we identified a positive correlation between Cdc42 activity and the frequency of HSCs upon aging.
The frequency of human HSCs polar fo...
Source: Fight Aging! - January 31, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
This is Not Health Care
By HANS DUVEFELT
We use the word health rather loosely in America today. Especially the expression health care, whether you spell that as one word or two, is almost an oxymoron.
Health is not simply the absence of disease, even less the pharmaceutical management of disease. The healthcare “industry” is not the major portion of our GNP that it is because there is a lot of health out there, but the opposite. What consumes so much money and generates so much profit is, of course, sick care. The sicker people are, the more money is spent and earned in this market segment. It is a spiral, and a vicious one.
Hea...
Source: The Health Care Blog - January 18, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Patients Physicians functional medicine Hans Duvefelt integrative health Source Type: blogs
Fight Aging! Newsletter, December 7th 2020
In this study, except for the reduction in body weight, the aging characteristics related to epidermal and muscle tissue in mice were significantly ameliorated in the CR group compared with the control group. Additional studies have indicated that not stem cells themselves but the stem cell microenvironment is the key factor mediating stem cell activation, proliferation and differentiation.
Mitochondrial dysfunction is an important factor leading to age-related muscular atrophy. Considering the dependence of skeletal muscle on ATP, loss of mitochondrial function, which can lead to a decrease in strength and enduranc...
Source: Fight Aging! - December 6, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, November 2nd 2020
In conclusion, the circulating antibody repertoire has increased binding to thousands of peptides in older donors, which can be represented as an immune age. Increased immune age is associated with autoimmune disease, acute inflammatory disease severity, and may be a broadly relevant biomarker of immune function in health, disease, and therapeutic intervention. The immune age has the potential for wide-spread use in clinical and consumer settings.
In Vivo Reprogramming Improves Cognitive Function in Old Mice
https://www.fightaging.org/archives/2020/10/in-vivo-reprogramming-improves-cognitive-function-in-old-mi...
Source: Fight Aging! - November 1, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
