Pneumothorax during manned chamber operations: A summary of reported cases
Undersea Hyperb Med. 2024 First Quarter;51(1):29-35.ABSTRACTIn-chamber pneumothorax has complicated medically remote professional diving operations, submarine escape training, management of decompression illness, and hospital-based provision of hyperbaric oxygen therapy. Attempts to avoid thoracotomy by combination of high oxygen partial pressure breathing (the concept of inherent unsaturation) and greatly slowed rates of chamber decompression proved successful on several occasions. When this delicate balance designed to prevent the intrapleural gas volume from expanding faster than it contracts proved futile, chest drains...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Richard E Clarke Keith Van Meter Source Type: research
Medical and surgical management of pneumothorax in diving and hyperbaric chambers
Undersea Hyperb Med. 2024 First Quarter;51(1):17-28.ABSTRACTThe presence of a pneumothorax within a pressurized chamber represents unique diagnostic and management challenges. This is particularly the case in the medical and geographic remoteness of many chamber locations. Upon commencing chamber decompression, unvented intrapleural air expands. If its initial volume and/or degree of chamber pressure reduction is significant enough, a tension pneumothorax will result. Numerous reports chronicle failure to diagnose and manage in-chamber pneumothorax with resultant morbidity and one fatal outcome. Such cases have occurred in...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Richard E Clarke Keith Van Meter Source Type: research
Pneumothorax during manned chamber operations: A summary of reported cases
Undersea Hyperb Med. 2024 First Quarter;51(1):29-35.ABSTRACTIn-chamber pneumothorax has complicated medically remote professional diving operations, submarine escape training, management of decompression illness, and hospital-based provision of hyperbaric oxygen therapy. Attempts to avoid thoracotomy by combination of high oxygen partial pressure breathing (the concept of inherent unsaturation) and greatly slowed rates of chamber decompression proved successful on several occasions. When this delicate balance designed to prevent the intrapleural gas volume from expanding faster than it contracts proved futile, chest drains...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Richard E Clarke Keith Van Meter Source Type: research
Medical and surgical management of pneumothorax in diving and hyperbaric chambers
Undersea Hyperb Med. 2024 First Quarter;51(1):17-28.ABSTRACTThe presence of a pneumothorax within a pressurized chamber represents unique diagnostic and management challenges. This is particularly the case in the medical and geographic remoteness of many chamber locations. Upon commencing chamber decompression, unvented intrapleural air expands. If its initial volume and/or degree of chamber pressure reduction is significant enough, a tension pneumothorax will result. Numerous reports chronicle failure to diagnose and manage in-chamber pneumothorax with resultant morbidity and one fatal outcome. Such cases have occurred in...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Richard E Clarke Keith Van Meter Source Type: research
Pneumothorax during manned chamber operations: A summary of reported cases
Undersea Hyperb Med. 2024 First Quarter;51(1):29-35.ABSTRACTIn-chamber pneumothorax has complicated medically remote professional diving operations, submarine escape training, management of decompression illness, and hospital-based provision of hyperbaric oxygen therapy. Attempts to avoid thoracotomy by combination of high oxygen partial pressure breathing (the concept of inherent unsaturation) and greatly slowed rates of chamber decompression proved successful on several occasions. When this delicate balance designed to prevent the intrapleural gas volume from expanding faster than it contracts proved futile, chest drains...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Richard E Clarke Keith Van Meter Source Type: research
Medical and surgical management of pneumothorax in diving and hyperbaric chambers
Undersea Hyperb Med. 2024 First Quarter;51(1):17-28.ABSTRACTThe presence of a pneumothorax within a pressurized chamber represents unique diagnostic and management challenges. This is particularly the case in the medical and geographic remoteness of many chamber locations. Upon commencing chamber decompression, unvented intrapleural air expands. If its initial volume and/or degree of chamber pressure reduction is significant enough, a tension pneumothorax will result. Numerous reports chronicle failure to diagnose and manage in-chamber pneumothorax with resultant morbidity and one fatal outcome. Such cases have occurred in...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Richard E Clarke Keith Van Meter Source Type: research
Pneumothorax during manned chamber operations: A summary of reported cases
Undersea Hyperb Med. 2024 First Quarter;51(1):29-35.ABSTRACTIn-chamber pneumothorax has complicated medically remote professional diving operations, submarine escape training, management of decompression illness, and hospital-based provision of hyperbaric oxygen therapy. Attempts to avoid thoracotomy by combination of high oxygen partial pressure breathing (the concept of inherent unsaturation) and greatly slowed rates of chamber decompression proved successful on several occasions. When this delicate balance designed to prevent the intrapleural gas volume from expanding faster than it contracts proved futile, chest drains...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Richard E Clarke Keith Van Meter Source Type: research
Medical and surgical management of pneumothorax in diving and hyperbaric chambers
Undersea Hyperb Med. 2024 First Quarter;51(1):17-28.ABSTRACTThe presence of a pneumothorax within a pressurized chamber represents unique diagnostic and management challenges. This is particularly the case in the medical and geographic remoteness of many chamber locations. Upon commencing chamber decompression, unvented intrapleural air expands. If its initial volume and/or degree of chamber pressure reduction is significant enough, a tension pneumothorax will result. Numerous reports chronicle failure to diagnose and manage in-chamber pneumothorax with resultant morbidity and one fatal outcome. Such cases have occurred in...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Richard E Clarke Keith Van Meter Source Type: research
Pneumothorax during manned chamber operations: A summary of reported cases
Undersea Hyperb Med. 2024 First Quarter;51(1):29-35.ABSTRACTIn-chamber pneumothorax has complicated medically remote professional diving operations, submarine escape training, management of decompression illness, and hospital-based provision of hyperbaric oxygen therapy. Attempts to avoid thoracotomy by combination of high oxygen partial pressure breathing (the concept of inherent unsaturation) and greatly slowed rates of chamber decompression proved successful on several occasions. When this delicate balance designed to prevent the intrapleural gas volume from expanding faster than it contracts proved futile, chest drains...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Richard E Clarke Keith Van Meter Source Type: research
Medical and surgical management of pneumothorax in diving and hyperbaric chambers
Undersea Hyperb Med. 2024 First Quarter;51(1):17-28.ABSTRACTThe presence of a pneumothorax within a pressurized chamber represents unique diagnostic and management challenges. This is particularly the case in the medical and geographic remoteness of many chamber locations. Upon commencing chamber decompression, unvented intrapleural air expands. If its initial volume and/or degree of chamber pressure reduction is significant enough, a tension pneumothorax will result. Numerous reports chronicle failure to diagnose and manage in-chamber pneumothorax with resultant morbidity and one fatal outcome. Such cases have occurred in...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Richard E Clarke Keith Van Meter Source Type: research
How hydrophobicity, side chains, and salt affect the dimensions of disordered proteins
AbstractDespite the generally accepted role of the hydrophobic effect as the driving force for folding, many intrinsically disordered proteins (IDPs), including those with hydrophobic content typical of foldable proteins, behave nearly as self-avoiding random walks (SARWs) under physiological conditions. Here, we tested how temperature and ionic conditions influence the dimensions of the N-terminal domain of pertactin (PNt), an IDP with an amino acid composition typical of folded proteins. While PNt contracts somewhat with temperature, it nevertheless remains expanded over 10 –58°C, with a Flory exponent,ν,>0.50. Bo...
Source: Protein Science - April 12, 2024 Category: Biochemistry Authors: Michael C. Baxa,
Xiaoxuan Lin,
Cedrick D. Mukinay,
Srinivas Chakravarthy,
Joseph R. Sachleben,
Sarah Antilla,
Nina Hartrampf,
Joshua A. Riback,
Isabelle A. Gagnon,
Bradley L. Pentelute,
Patricia L. Clark,
Tobin R. Sosnick Tags: RESEARCH ARTICLE Source Type: research
Commonality and heterogeneity of pacemaker mechanisms in the male reproductive organs
J Physiol. 2024 Apr 12. doi: 10.1113/JP284756. Online ahead of print.ABSTRACTDuring emission, the first phase of ejaculation, smooth muscle in organs of the male reproductive tract (MRT) vigorously contract upon sympathetic nerve excitation to expel semen consisting of sperm and seminal plasma. During inter-ejaculation phases, the epididymis, seminal vesicles and prostate undergo spontaneous phasic contractions (SPCs), this transporting and maintaining the quality of sperm and seminal plasma. Recent studies have revealed platelet-derived growth factor receptor α-expressing (PDGFRα+) subepithelial interstitial cells in se...
Source: The Journal of Physiology - April 12, 2024 Category: Physiology Authors: Hikaru Hashitani Mitsue Takeya Dirk F van Helden Source Type: research
Commonality and heterogeneity of pacemaker mechanisms in the male reproductive organs
J Physiol. 2024 Apr 12. doi: 10.1113/JP284756. Online ahead of print.ABSTRACTDuring emission, the first phase of ejaculation, smooth muscle in organs of the male reproductive tract (MRT) vigorously contract upon sympathetic nerve excitation to expel semen consisting of sperm and seminal plasma. During inter-ejaculation phases, the epididymis, seminal vesicles and prostate undergo spontaneous phasic contractions (SPCs), this transporting and maintaining the quality of sperm and seminal plasma. Recent studies have revealed platelet-derived growth factor receptor α-expressing (PDGFRα+) subepithelial interstitial cells in se...
Source: The Journal of Physiology - April 12, 2024 Category: Physiology Authors: Hikaru Hashitani Mitsue Takeya Dirk F van Helden Source Type: research
A university cut tenured faculty ’s pay. They’re suing
Along with a secure post and academic freedom, tenured professors enjoy financial security—or so many outsiders imagine. In fact, many tenured faculty are expected to cover much of their salary with grants, and may be penalized with salary reductions if they do not. That’s what happened at Tufts University School of Medicine—and some researchers are fighting back.
Last month, the Massachusetts Supreme Judicial Court sent a case brought by eight of the school’s faculty members to trial,
writing that their claims have merit
: “Tenure would seem to be a hollow promise if it came without any salary co...
Source: Science of Aging Knowledge Environment - April 10, 2024 Category: Geriatrics Source Type: research
Type selective ablation of postnatal slow and fast fatigue-resistant motor neurons in mice induces late onset kinetic and postural tremor following fiber-type transition and myopathy
Exp Neurol. 2024 Apr 8:114772. doi: 10.1016/j.expneurol.2024.114772. Online ahead of print.ABSTRACTAnimals on Earth need to hold postures and execute a series of movements under gravity and atmospheric pressure. VAChT-Cre is a transgenic Cre driver mouse line that expresses Cre recombinase selectively in motor neurons of S-type (slow-twitch fatigue-resistant) and FR-type (fast-twitch fatigue-resistant). Sequential motor unit recruitment is a fundamental principle for fine and smooth locomotion; smaller-diameter motor neurons (S-type, FR-type) first contract low-intensity oxidative type I and type IIa muscle fibers, and the...
Source: Experimental Neurology - April 10, 2024 Category: Neurology Authors: Hidemi Misawa Kai Kamishima Tenkei Koyama Lisa Ohgaki Yuta Morisaki Tomoyuki Yamanaka Shigeyoshi Itohara Shoko Sawano Wataru Mizunoya Naomichi Ogihara Source Type: research
