TWiV 1002: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses completeness and spin of medRxiv preprints and associated published abstracts of COVID-19 randomized clinical trials, lessons learned from a COVID-19 dog screening pilot in California K-12 schools, SARS-CoV-2 reinfection and severity of the disease, effectiveness of COVID-19 bivalent vaccine, Molnupiravir and risk of post-acute sequelae of COVID-19, risk of new-onset long Covid following reinfection with SARS-CoV-2, low vitamin D levels associated with long COVID syndrome in COVID-19 survivors, and clinical experience with the α2A-adrenoceptor agonist, guanfacine, an...
Source: This Week in Virology - MP3 Edition - April 29, 2023 Category: Virology Authors: VIncent Racaniello Source Type: podcasts
Audio long read: Conquering Alzheimer ’s — a look at the therapies of the future
Last year, researchers announced that the Alzheimer’s drug lecanemab lowered the amount of amyloid protein plaques associated with the disease in the brains of participants in a clinical trial, and slowed their cognitive decline.Now, researchers are looking to drug combinations, vaccines and gene therapy to tackle different stages of the disease, as they forge the next generation of treatments for the condition.This is an audio version of our Feature: Conquering Alzheimer’s: a look at the therapies of the future Hosted on Acast. See acast.com/privacy for more information. (Source: Nature Podcast)
Source: Nature Podcast - April 28, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts
JAMA Oncology : Radiosurgery of Spine Metastasis —NRG/RTOG 0631 RCT Final Results
Interview with Samuel Ryu, MD, author of Stereotactic Radiosurgery vs Conventional Radiotherapy for Localized Vertebral Metastases of the Spine: Phase 3 Results of NRG Oncology/RTOG 0631 Randomized Clinical Trial. Hosted by Jack West, MD. Related Content: Stereotactic Radiosurgery vs Conventional Radiotherapy for Localized Vertebral Metastases of the Spine (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - April 20, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
JAMA Surgery : Outcomes Following Laparoscopic Elective Sigmoid Resection vs Conservative Treatment Following Diverticulitis
Interview with Ville Sallinen, MD, PhD, and Alexandre Santos, MD, authors of Quality-of-Life and Recurrence Outcomes Following Laparoscopic Elective Sigmoid Resection vs Conservative Treatment Following Diverticulitis: Prespecified 2-Year Analysis of the LASER Randomized Clinical Trial. Hosted by Amalia Cochran, MD. Related Content: Quality-of-Life and Recurrence Outcomes Following Laparoscopic Elective Sigmoid Resection vs Conservative Treatment Following Diverticulitis (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - April 19, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
JAMA Otolaryngology –Head & Neck Surgery : Effectiveness of Self-fitting vs Audiologist-Fitted Hearing Aids
Interview with Karina C. De Sousa, PhD, author of Effectiveness of an Over-the-Counter Self-fitting Hearing Aid Compared With an Audiologist-Fitted Hearing Aid: A Randomized Clinical Trial. Hosted by Paul C. Bryson, MD, MBA. Related Content: Effectiveness of an Over-the-Counter Self-fitting Hearing Aid Compared With an Audiologist-Fitted Hearing Aid (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - April 13, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
Giant black-hole pair from the early Universe gives clues to how galaxies form
00:46 A pair of supermassive black holes in the distant universeSupermassive black holes are found at the centre of galaxies across the universe. But observations of galaxies with more than one – caused by the merging of two galaxies – have been rare. Now, researchers have combined data from a number of telescopes and satellites, to reveal a pair of supermassive blackholes farther from Earth than any pair detected previously. They hope this will offer insights into how galaxies form.Research article: Chen et al.News and Views: Distant supermassive black holes spotted in galaxy merger10:53 Research HighlightsWhy appetit...
Source: Nature Podcast - April 5, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts
JAMA Oncology : Pathologic Complete Response and Clinical Outcomes in Soft Tissue Sarcoma
Interview with Dian Wang, MD, author of Pathologic Complete Response and Clinical Outcomes in Patients With Localized Soft Tissue Sarcoma Treated With Neoadjuvant Chemoradiotherapy or Radiotherapy: The NRG/RTOG 9514 and 0630 Nonrandomized Clinical Trials. Hosted by Jack West, MD. Related Content: Pathologic Complete Response and Clinical Outcomes in Patients With Localized Soft Tissue Sarcoma Treated With Neoadjuvant Chemoradiotherapy or Radiotherapy (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - March 30, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
JAMA Surgery : Effect of Breast Reconstruction With Autologous Fat Transfer vs Implants on Quality of Life
Interview with Andrzej A. Piatkowski, MD, PhD, author of Effect of Total Breast Reconstruction With Autologous Fat Transfer Using an Expansion Device vs Implants on Quality of Life Among Patients With Breast Cancer: A Randomized Clinical Trial. Hosted by Amalia Cochran, MD. Related Content: Effect of Total Breast Reconstruction With Autologous Fat Transfer Using an Expansion Device vs Implants on Quality of Life Among Patients With Breast Cancer (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - March 1, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
JAMA Neurology : Optimal Intensity and Duration of Walking Rehabilitation in Patients With Chronic Stroke
Interview with Pierce Boyne, PT, DPT, PhD, NCS, author of Optimal Intensity and Duration of Walking Rehabilitation in Patients With Chronic Stroke: A Randomized Clinical Trial. Hosted by Cynthia E. Armand, MD. Related Content: Optimal Intensity and Duration of Walking Rehabilitation in Patients With Chronic Stroke (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - February 23, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
A twisting microscope that could unlock the secrets of 2D materials
00:45 A new microscope to look for ‘magic’ anglesTo better visualise how electrons are ‘moving’ in materials, a team have developed the Quantum Twisting Microscope. This instrument puts two 2D layers of atoms into close contact, allowing them to interact, which can give useful information about their properties. The microscope can also rotate one of the layers, helping researchers look for so-called ‘magic angles’, where 2D materials like graphene can exhibit extraordinary properties.Research article: Inbar et al.News & Views: A twist in the bid to probe electrons in solids09:55 Research HighlightsHow an ex...
Source: Nature Podcast - February 22, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts
JAMA Cardiology : Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care
Interview with Søren Zöga Diederichsen, MD, PhD, author of Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care: Post Hoc Analysis of the LOOP Randomized Clinical Trial, and Mark Schoenfeld, MD, author of Incidental Detection of Bradycardia by Implantable Loop Recorders—Unintended Consequences. Hosted by Kristen K. Patton, MD. Related Content: Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care Incidental Detection of Bradycardia by Implantable Loop Recorders—Unintended Consequences (Sour...
Source: JAMA Specialty Journals Author Interviews - February 15, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
TWiV 976: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses China reporting almost 60,000 Covid-related deaths after abrupt shift in policy, detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination, effect of Fluvoxamine vs placebo on time to sustained recovery in outpatients with mild to moderate COVID-19, hyperimmune globulin for severely immunocompromised patients hospitalized with COVID-19, long COVID outcomes at one year after mild SARS-CoV-2 infection, long COVID: major findings, mechanisms and recommendations, a systematic review of trials currently inves...
Source: This Week in Virology - MP3 Edition - January 21, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
JAMA Psychiatry : Effect of Technology-Enhanced Screening Plus Standard Clinician Education on the Duration of Untreated Psychosis
Interview with Cameron S. Carter, MD, author of Effect of Technology-Enhanced Screening in Addition to Standard Targeted Clinician Education on the Duration of Untreated Psychosis: A Cluster Randomized Clinical Trial. Hosted by John Torous, MD, MBI, and Kara Bagot, MD. Related Content: Effect of Technology-Enhanced Screening in Addition to Standard Targeted Clinician Education on the Duration of Untreated Psychosis (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - January 4, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
JAMA Surgery : Cost-effectiveness of Laparoscopic vs Open Gastrectomy
Interview with Arjen van der Veen, MD, PhD, and Richard van Hillegersberg, MD, PhD, authors of Cost-effectiveness of Laparoscopic vs Open Gastrectomy for Gastric Cancer: An Economic Evaluation Alongside a Randomized Clinical Trial. Hosted by Amalia Cochran, MD. Related Content: Cost-effectiveness of Laparoscopic vs Open Gastrectomy for Gastric Cancer (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - December 27, 2022 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
SCCM Pod-463 CCM: Clazakizumab for COVID-19: Friend or Foe?
Clazakizumab is a monoclonal antibody against human interleukin-6 that may benefit patients hospitalized with severe or critical COVID-19 accompanied by hyperinflammation. Although not yet FDA approved, clinical trials of clazakizumab for treatment of COVID-19 are under way worldwide. Samantha Gambles Farr, MSN, NP-C, CCRN, RNFA, is joined by Bonnie E. Lonze, MD, PhD, to discuss the article, A Randomized Double-Blinded Placebo Controlled Trial of Clazakizumab for the Treatment of COVID-19 Pneumonia With Hyperinflammation, published in the September 2022 issue of Critical Care Medicine. Dr. Lonze is a faculty transplant sur...
Source: SCCM PodCast - iCritical Care - December 21, 2022 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts
