Talk evidence covid-19 update - natural history of covid, include patients in guidelines
For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing.
We're going to try to get away from the headlines and talk about what we need to know - to hopefully give you some insight into these issues.
This week:
(1.20) Carl gives us an update on the England and Wales admission data.
(3.00) Helen talks about ways in which spread and severity of infection amongst household contacts.
(8.20) We talk natural history of covid-19, and Harlan Krumho...
Source: The BMJ Podcast - May 9, 2020 Category: General Medicine Authors: BMJ Group Source Type: podcasts
When Should Physicians Act on Non –Statistically Significant Results From Clinical Trials?
Interview with Paul J. Young, PhD, author of When Should Clinicians Act on Non–Statistically Significant Results From Clinical Trials? (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - May 8, 2020 Category: General Medicine Authors: JAMA Network Source Type: podcasts
JAMA Dermatology : Face-Aging Mobile App –Based Intervention on Skin Cancer Protection Behavior
Interview with Titus Josef Brinker, MD, author of Effect of a Face-Aging Mobile App–Based Intervention on Skin Cancer Protection Behavior in Secondary Schools in Brazil: A Cluster-Randomized Clinical Trial (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - May 6, 2020 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
SCCM Pod-413 COVID-19 Fact Versus Science Fiction
Explore the need for randomized COVID-19 clinical trials and the difficulties and potential consequences of misinformation with host Ashish K. Khanna, MD, FCCP, FCCM, and Nicholas E. Ingraham, MD. (Source: SCCM PodCast - iCritical Care)
Source: SCCM PodCast - iCritical Care - May 1, 2020 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts
TWiV 608: Daniel Griffin's COVID-19 clinical report
Daniel Griffin updates the clinical situation with COVID-19 patients, followed by analysis of the remedesivir clinical trial results, and answers listener questions. Hosts: Vincent Racaniello and Rich Condit Guest: Daniel Griffin Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Pulmonary embolism in COVID-19 (Emerg Inf Dis) Patch Study Remdesivir in adults with severe COVID-19 (Lancet) ACTT remdesivir trial (NIAID) Commentary on remdesivir trials (Lancet) FDA expected to issue remdesivir EUA (Contaigon Live) Recovered COVID-19 patients wrong (Korea Herald) Letter...
Source: This Week in Virology - MP3 Edition - May 1, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
FDA cautions against use of hydroxychloroquine or chloroquine for COVID-19 outside of the hospital setting or a clinical trial due to risk of heart rhythm problems
Listen to an audio podcast of the April 24, 2020 FDA Drug Safety Communication: FDA cautions against use of hydroxychloroquine or chloroquine for COVID-19 outside of the hospital setting or a clinical trial due to risk of heart rhythm problems. Close supervision is recommended (Source: FDA Drug Safety Podcasts)
Source: FDA Drug Safety Podcasts - April 24, 2020 Category: Drugs & Pharmacology Authors: U.S. Food and Drug Administration, Center for Drug Evaluation and Research U.S. Food and Drug Administration, Center for Drug Evaluation and Research Source Type: podcasts
Irregularities and Misconduct in Clinical Trials: Increasing Access to FDA Inspection Reports
Interview with Aaron S. Kesselheim, MD, JD, MPH, author of Increasing Access to FDA Inspection Reports on Irregularities and Misconduct in Clinical Trials (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - April 23, 2020 Category: General Medicine Authors: JAMA Network Source Type: podcasts
JAMA Internal Medicine : Effect of a Mammography Screening Decision Aid for Women 75 Years and Older
Interview with Mara A. Schonberg, MD, MPH, author of Effect of a Mammography Screening Decision Aid for Women 75 Years and Older: A Cluster Randomized Clinical Trial, and Quyen Ngo-Metzger, MD, MPH, author of The Life and Death of Mammograms in Patients 75 Years and Older—To Screen or Not to Screen? (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - April 20, 2020 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
Diabetes Core Update: Therapeutic Inertia – April 2020
In this first episode of a three-part series on “Disrupting Therapeutic Inertia in Diabetes Management,” Drs. John Russell and Neil Skolnik examine a case study of a 55-year-old man with type 2 diabetes (3 years duration, A1C 8.2%). In so doing, they review six articles that define achievement gaps in reaching A1C goals and the reasons for why those gaps exist. In episodes 2 and 3 of this series, Drs. Russell and Skolnik we will look at additional causes of therapeutic inertia and solutions for overcoming it. This special three-part series on therapeutic inertia is supported by independent educational grant from Sanofi...
Source: Diabetes Core Update - April 14, 2020 Category: Endocrinology Authors: American Diabetes Association Source Type: podcasts
JAMA Oncology : Durvalumab With or Without Tremelimumab vs Standard Chemotherapy for Metastatic NSCLC
Interview with Naiyer A. Rizvi, MD, author of Durvalumab With or Without Tremelimumab vs Standard Chemotherapy in First-line Treatment of Metastatic Non–Small Cell Lung Cancer: The MYSTIC Phase 3 Randomized Clinical Trial (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - April 9, 2020 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
TWiV 592: Coronavirus update - dangerous curve ahead
Ori joins TWiV for an update on the SARS-CoV-2 pandemic, including scary modeling, clinical trials for antivirals and vaccines, asymptomatic transmission, and much more inspired by listener email. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Guest: Ori Lieberman Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Scary modeling (Imperial College London) Avigan vs SARS-CoV-2 (NHK) SARS-CoV-2 mRNA vaccine (Clinical Trials) SARS-CoV-2 stability (NEJM) Pediatric COVID-19 (one, two) SARS-CoV-2 asymptomatic infection (one, two) CDC data on SARS-CoV-2 CFR (MMWR) H...
Source: This Week in Virology - MP3 Edition - March 19, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
JAMA Surgery : Robotic Approach vs Traditional Laparoscopic Approach and Postoperative Outcomes
Interview with Ajita S. Prabhu, MD, and Michael J Rosen, MD, FACS, authors of Robotic Inguinal vs Transabdominal Laparoscopic Inguinal Hernia Repair: The RIVAL Randomized Clinical Trial (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - March 18, 2020 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
TWiV 588: Coronavirus update - Save the pangolin!
The TWiV team returns this week to SARS-CoV-2019 coverage to review the latest epi curves, the fatality rate, furin cleavage site and receptor binding domain in the spike glycoprotein, related CoV recovered from pangolins, evidence that the virus did not escape from a laboratory, and many more questions sent in by listeners. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode WHO CoV sitreps Epidemiology of COVID-19 (China CDC) COVID-19 incubation period (J Med Virol) China clinical tria...
Source: This Week in Virology - MP3 Edition - February 23, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
