CFTR modulation for those with ONE copy of DDF508?
Does anyone have info on cftr modulation drugs for people that carry only one copy of the DDF508 mutation, and another of..something else? My other mutation is a nonsense mutation. Are any clinical trials going on for those of us in this boat? Or is there any research on Kalydeco combined with other drugs for the patients with one ddf508? Thanks! (Source: Cystic Fibrosis CFTR Modulation and Gene Therapy Forum)
Source: Cystic Fibrosis CFTR Modulation and Gene Therapy Forum - February 6, 2015 Category: Respiratory Medicine Authors: sasha Tags: CFTR Modulation and Gene Therapy Talk Source Type: forums
Re: Clinical trials: what a waste
(Source: BMJ Comments)
Source: BMJ Comments - January 20, 2015 Category: Journals (General) Source Type: forums
Ascertainment or detection bias or measurement bias can be minimized by double blinding the treatment allocation in a clinical trial
(Source: BMJ Comments)
Source: BMJ Comments - January 3, 2015 Category: Journals (General) Source Type: forums
Re: SearCh for humourIstic and Extravagant acroNyms and Thoroughly Inappropriate names For Important Clinical trials (SCIENTIFIC): qualitative and quantitative systematic study
(Source: BMJ Comments)
Source: BMJ Comments - December 20, 2014 Category: Journals (General) Source Type: forums
Re: Clinical trials: what a waste
(Source: BMJ Comments)
Source: BMJ Comments - December 19, 2014 Category: Journals (General) Source Type: forums
Using engineered probiotic bacteria for treating Pseudomonas-induced lung infection
Hi everyone,
I am a member of a research group that engineered a commensal probiotic bacteria from the human gut to seek and kill Pseudomonas aeruginosa. This work is currently undergoing pre-clinical trial and we hope to reach clinical trial stage in a few years to treat Pseudomonas infections, which potentially include lung infections induced by Pseudomonas. In anticipation of the difficulties we may encounter in researching and promoting this treatment, we are conducting this short survey to understand the perspectives of healthcare specialists, patients and the public on this form of treatment. We hope that ...
Source: Cystic Fibrosis Alternative Medicine Forum - September 30, 2014 Category: Respiratory Medicine Authors: jlfoo Tags: Alternative Medicine Source Type: forums
Clinical trials
Forum: Health
Posted By: Amphiprion
Post Time: 29-07-2014 at 22:27 (Source: The Student Room)
Source: The Student Room - July 30, 2014 Category: Universities & Medical Training Source Type: forums
Clinical Trial for kids ages 6 and up with DD508
Hi!
I was wondering if anyone has heard what is going on with the clinical trial for the combo of the Kalydeco/VX-809 for kids ages 6 and up. Our hospital was chosen as one of the sites and my son's doctor had mentioned it a few months ago... I followed up with her about it today and she said it had been put on hold. Does anyone know why? Thank you! (Source: Cystic Fibrosis CFTR Modulation and Gene Therapy Forum)
Source: Cystic Fibrosis CFTR Modulation and Gene Therapy Forum - June 17, 2014 Category: Respiratory Medicine Authors: mbrandazzo Tags: CFTR Modulation and Gene Therapy Talk Source Type: forums
How does taking part in paid clinical trials affect the benefits that I receive
Forum: Money and finance
Posted By: kelpic
Post Time: 25-03-2014 at 22:51 (Source: The Student Room)
Source: The Student Room - March 26, 2014 Category: Universities & Medical Training Source Type: forums
FDA Investigation Finds No Excess Bleeding Risk for Dabigatran
In its latest assessment of a highly controversial issue, the FDA has found no indication that bleeding rates for dabigatran (Pradaxa, Boehringer-Ingelheim) are any higher than the bleeding rates for warfarin. The FDA investigation was in response to the large number of post-marketing reports of bleeding in people taking dabigatran. Click here to for the full FDA statement. Here is the first paragraph of the statement:
The U.S. Food and Drug Administration (FDA) has evaluated new information about the risk of serious bleeding associated with use of the anticoagulants (blood thinners) dabigatran (Pradaxa) and warfarin (Co...
Source: CardiologyNetwork.com - October 13, 2013 Category: Cardiology Authors: Indian Diabetics Foundation Team Source Type: forums
response to a comment
Discussion. Paradox effects of vitamin D maybe due to the different doses of it.One explantation could be that vitamin D has it,s effects on insulin resistance in a specific level and in lower or higher level or doses ,it may have paradox effects maybe because of the effects on different genes in nucleus and DNA.The difference of results of different studies about the effect of vitamin D on insulin resistance maybe due to different dosage and serum levels for vitamin D that used in different studies.
3- We suggest a model for predicting Fasting Plasma Glucose. It should be used in more studies and different clinical t...
Source: Diabetology and Metabolic Syndrome Comments - June 27, 2013 Category: Endocrinology Authors: afsaneh talaei Source Type: forums
