A Virtual Care Platform for Respiratory Illness: Interview with Stacie Ruth, CEO of AireHealth
AireHealth, a medtech company based in Orlando, Florida, currently offers a portable nebulizer and companion app for respiratory patients aged two and over. The small nebulizer can be charged using a micro USB charger and then placed in a bag or pocket for easy transport and use on the move. The companion app is geared toward increasing patient engagement and medication adherence, which is important in maximizing therapeutic outcomes among chronic respiratory patients. Recently, AireHealth announced a merger with BreathResearch, a respiratory healthcare company based in Silicon Valley that specializes in detection and m...
Source: Medgadget - July 2, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Informatics Medicine Telemedicine AireHealth Source Type: blogs

Escaping COVID-19
By RAGHAV GUPTA, MD “In seeking absolute truth, we aim at the unattainable and must be content with broken portions.” William Osler A colleague shared an experience with me about testing one of his patients for the novel coronavirus and it left me a bit puzzled.  An elderly gentleman with past medical history of severe COPD (chronic obstructive pulmonary disease) and heart failure came to the ER with shortness of breath, edema and fatigue.  Chest x-day suggested pulmonary edema.  He wanted to test him for SARS-CoV2 but hesitated.  Eventually he was able to order it ...
Source: The Health Care Blog - June 4, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Uncategorized Source Type: blogs

Fight Aging! Newsletter, May 25th 2020
In conclusion, our results suggest a previously unknown mechanism whereby the canonical NF-κB cascade and a mitochondrial fission pathway interdependently regulate endothelial inflammation. Lin28 as a Target for Nerve Regeneration https://www.fightaging.org/archives/2020/05/lin28-as-a-target-for-nerve-regeneration/ Researchers here show that the gene Lin28 regulates axon regrowth. In mice, raised levels of Lin28 produce greater regeneration of nerve injuries. Past research has investigated Lin28 from the standpoint of producing a more general improvement in regenerative capacity. It improves mitochondr...
Source: Fight Aging! - May 24, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Cellular Senescence in Lung Disease
Today's open access paper is a review of what is known of the role of cellular senescence in lung disease. With the development of senolytic therapies that can selectively destroy senescent cells, all conditions in which senescent cells contribute meaningfully to pathology may soon be effectively treated. Senescent cells accumulate with age in all tissues, and while never a sizable fraction of all cells, even a comparatively small number of senescent cells can cause chronic inflammation and tissue dysfunction. They secrete a mix of inflammatory signals, growth factors, and other molecules that has a sizable effect on the b...
Source: Fight Aging! - May 20, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Is there an entity called “ Isolated ” systolic pulmonary arterial hypertension ?
What is the incidence of Isolated systolic pulmonary arterial hypertension (ISPAH) and its Implication? We attempted to answer this question and found some interesting answers. It was published in the Indian heart journal  December 2007 Abstract issue. More than a decade gone. I think this issue is still largely misunderstood. Fellows may pursue this. One more parameter that can be explored is pulmonary artery pulse pressure and effect on progressive pulmonary vascular disease and PVR. Mean while  PAH definition and classification has changed many times, ISPAH definitely requires a place in the new scheme of things. The ...
Source: Dr.S.Venkatesan MD - May 15, 2020 Category: Cardiology Authors: dr s venkatesan Tags: Pulmonary arterial hypertension Pulmonary circulation Pulmonary vascular resistance Thesis/Research topics for cardiology fellows isolated pulmonary arterial hypertension ispah normal pulmoanry arterial pressure pulmonary hypertension syst Source Type: blogs

Adding Voice to Respiratory and Cardiovascular Disease Diagnosis: Interview with Prof. Elad Maor
The field of telehealth is growing thanks to the steady growth in supportive technology and the need for remote monitoring, assessment, diagnosis, and testing. Voice is unique to every individual due to people’s anatomical differences, which makes for a powerful tool when working remotely. Vocalis Health is a company that uses machine learning and artificial intelligence to identify biomarkers in voice recordings. The company’s technology has been successfully used to identify mortality and hospitalization among heart failure patients. Vocalis is now adapting their technology to understand the associati...
Source: Medgadget - April 29, 2020 Category: Medical Devices Authors: Rukmani Sridharan Tags: Cardiology Diagnostics Exclusive Public Health Source Type: blogs

Will the Covid-Induced Telemedicine Scramble Change Primary Care Forever?
By HANS DUVEFELT, MD After my posts on telemedicine were published recently, (this one on Manly Wellness before the pandemic and this one after it erupted, on A Country Doctor Writes, then reblogged on The Health Care Blog, KevinMD and many others), I have been asked about my views on telemedicine’s role in the future of primary care. Things have changed quickly, and a bit chaotically, and there is a lot of experimentation happening right now in practices I work or speak with. Before thinking about telemedicine in Primary Care, we need to agree on some sort of definition of primary care, because ...
Source: The Health Care Blog - April 27, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Medical Practice primary care Telehealth Telemedicine Source Type: blogs

Oxygen Concentrator for N95 Masks to Make Breathing Easier
Paramedics, ICU staff, and anyone else currently working with patients in any capacity is probably wearing a face mask for extended periods of time. N95 masks, which are easy to wear while providing substantial protection, can reduce the amount of oxygen reaching the lungs by up to 20%. This causes fatigue, may lower blood-oxygen saturation, and lead staff to work shorter hours or even force them to pull their masks off the face frequently to get breathers. Now, researchers at Stanford University, who typically work on fuel cells for cars, have developed an oxygen concentrator that can be interfaced with N95 masks to provi...
Source: Medgadget - April 17, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Cardiology Materials Medicine Public Health Source Type: blogs

COVID-19: Hidden Coinfections and Chain Reactions Parasitic Infectious Relationships within Us
By SIMON YU, MD, LT COL, USA (Ret) Dr. Tom Frieden, former director of the Centers for Disease Control and Prevention (CDC), opened up a new front in the Coronavirus War by saying we don’t just need to treat the acute disease, we need to treat the underlying conditions that make people more susceptible to serious disease progression. He focused on heart disease, and managing mitigating risk factors such as CVD, diabetes, hypertension and smoking in order to increase people’s odds for recovery. The initial focus has been pneumonia and acute respiratory distress syndrome (ARDS), with risk factors including asthma, chr...
Source: The Health Care Blog - April 15, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 CDC chronic disease holistic care Pandemic SDoH Source Type: blogs

HATCH score for progression from paroxysmal to persistent AF
HATCH score for prediction of progression from paroxysmal to persistent atrial fibrillation (AF) checks the following: heart failure, age, previous transient ischemic attack or stroke, chronic obstructive pulmonary disease, and hypertension [1]. For the analysis, the authors used over 1200 patients with paroxysmal AF who participated in Euro Heart Survey on AF. Those who had progression of AF after one year of follow up were noted. The components and weightage given in HATCH score were as follows: Hypertension: 1 Age 75 years or more: 1 Transient ischemic attack or stroke: 2 Chronic obstructive pulmonary disease: 1 Heart ...
Source: Cardiophile MD - April 14, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs

Health coaching is effective. Should you try it?
In the fall of 2019, my hospital put out word that it was looking for physicians who might wish to undergo intensive training to become certified health and wellness coaches. Having worked with patients who have used health coaching, I jumped at the chance. Their experiences were almost universally positive: many of them had attained health goals that had been otherwise elusive, such as the weight loss they invoked annually — and fruitlessly — as a New Year’s resolution. The few physicians I knew who were also coaches seemed to be able to fuse the different skill sets in a way that expanded their ability to connect w...
Source: Harvard Health Blog - April 8, 2020 Category: Consumer Health News Authors: Peter Grinspoon, MD Tags: Behavioral Health Exercise and Fitness Healthy Eating Mind body medicine Nutrition Prevention Stress Source Type: blogs

Fight Aging! Newsletter, April 6th 2020
This study delves into the mechanisms by which a short period of fasting can accelerate wound healing. Fasting triggers many of the same cellular stress responses, such as upregulated autophagy, as occur during the practice of calorie restriction. It isn't exactly the same, however, so it is always worth asking whether any specific biochemistry observed in either case does in fact occur in both situations. In particular, the period of refeeding following fasting appears to have beneficial effects that are distinct from those that occur while food is restricted. Multiple forms of therapeutic fasting have been repor...
Source: Fight Aging! - April 5, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Age-Slowing Interventions in the Context of Lung Aging
Researchers here consider a very conservative set of interventions known to modestly slow the progression of aging in laboratory species, largely by altering metabolism to upregulate beneficial cellular stress responses. The researchers look through the lens of lung aging, specifically, reviewing the evidence for these therapies to slow the deterioration in lung function and onset of lung disease in older individuals, or to be the basis for treating established lung disease. To date, the most reliable, best-researched way to extend life span is through the practice of calorie restriction (CR), which involves reduc...
Source: Fight Aging! - April 1, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Pulsus paradoxus – MCQ – Answer
Pulsus paradoxus – MCQ – Answer Pulsus paradoxus represents – Correct answer: a) Exaggerated inspiratory fall in blood pressure Normally there is an inspiratory fall in blood pressure of less than 10 mm Hg. This fall is exaggerated in pulsus paradoxus and can be noted in cardiac tamponade and severe obstructive pulmonary disease. In cardiac tamponade,  right heart compression prevents inspiratory increase in flow to the right heart and exaggerates the usual drop in venous return to the left heart resulting in fall of blood pressure. In chronic obstructive pulmonary disease, the swings in venous return oc...
Source: Cardiophile MD - March 26, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs

Respirix for Non-Invasive Cardiopulmonary Monitoring: Interview with CEO Eric Kriegstein
For patients with cardiopulmonary illnesses such as chronic obstructive pulmonary disease (COPD or congestive heart failure (CHF), few technologies exist to effectively monitor and manage their conditions in a convenient way. Pulmonary artery catheters and implants, that can help with monitoring, have successfully reduced heart failure hospitalizations, but these implants are highly invasive and costly. Respirix is developing a non-invasive device that aims to detect CHF decompensation and COPD exacerbation before patients experience symptoms. Cardiospire works by mining non-invasive physiological data gathered from wh...
Source: Medgadget - March 17, 2020 Category: Medical Devices Authors: Cici Zhou Tags: Cardiac Surgery Cardiology Exclusive Medicine Telemedicine Source Type: blogs