Trial By Error: Psych Issues Do Not Predict ME/CFS, New Chicago Study Shows
By David Tuller, DrPH For decades, investigators have argued over the causes of the illness or cluster of illnesses variously called myalgic encephalomyelitis (ME), chronic fatigue syndrome (CFS), ME/CFS, CFS/ME and other names. In the absence of an adequate explanation for the debilitating symptoms, a flawed approach to intervention based on the perceived need for […] (Source: virology blog)
Source: virology blog - December 30, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs
Trial By Error: Thoughts on The Observer, The Guardian, and Paradigm Shift
By David Tuller, DrPH Earlier this week, I blogged about a story in The Observer that provided an inaccurate description of what it called chronic fatigue syndrome. For much of the piece, the writer, Eleanor Morgan, offered a sympathetic portrait of people, including herself, experiencing prolonged symptoms after an acute bout of Covid-19. A lot […] (Source: virology blog)
Source: virology blog - December 2, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized Guardian observer shepherd Weir Source Type: blogs
Trial By Error: My Letter to BMJ Paediatrics Open about the CBT-Music Therapy Study
This study was published in April by BMJ […] (Source: virology blog)
Source: virology blog - November 25, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized BMJ music therapy norway Pediatrics Source Type: blogs
Trial By Error: Update on BMJ ’ s CBT-Music Therapy Study (h/t Steinkopf and Tack)
By David Tuller, DrPH I have written multiple posts this year about a Norwegian study of cognitive behavior therapy plus music therapy as a treatment for chronic fatigue after acute EBV infection (aka mononucleosis and glandular fever). The study, published in April by BMJ Paediatrics Open, was rife with methodological and ethical flaws. It should not have […] (Source: virology blog)
Source: virology blog - November 24, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized BMJ CBT music therapy Nina Steinkopf norway Tack Source Type: blogs
Long COVID: 8 Ways Digital Health Can Address The Symptoms
Yes, the COVID-19 pandemic is long. Since the WHO characterised the virus’ spread as a pandemic in March, cases have been climbing; countries are facing a second wave and are entering lockdown 2.0; and many aspects of our current lifestyle will continue through 2021. But this isn’t what we mean by “long COVID.” This newly-minted term refers to patients experiencing long-term sequelae of a COVID infection.
It’s not an exact medical term as it is a patient-made one apparently first used by Elisa Perego in a tweet to describe her own experience. Additionally, two patients can have different #longcovid experiences...
Source: The Medical Futurist - November 17, 2020 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Artificial Intelligence in Medicine E-Patients Health Sensors & Trackers Healthcare Design Healthcare Policy Portable Medical Diagnostics Telemedicine & Smartphones AI diabetes lumosity wearables sleep tracking Fitbit mental heal Source Type: blogs
Our Top 8 Digital Health Solutions Addressing Long COVID
Yes, the COVID-19 pandemic is long. Since the WHO characterised the virus’ spread as a pandemic in March, cases have been climbing; countries are facing a second wave and are entering lockdown 2.0; and many aspects of our current lifestyle will continue through 2021. But this isn’t what we mean by “long COVID.” This newly-minted term refers to patients experiencing long-term sequelae of a COVID infection.
It’s not an exact medical term as it is a patient-made one apparently first used by Elisa Perego in a tweet to describe her own experience. Additionally, two patients can have different #longcovid experiences...
Source: The Medical Futurist - November 17, 2020 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Artificial Intelligence in Medicine E-Patients Health Sensors & Trackers Healthcare Design Healthcare Policy Portable Medical Diagnostics Telemedicine & Smartphones AI diabetes lumosity wearables sleep tracking Fitbit mental heal Source Type: blogs
Illness-related fatigue: More than just feeling tired
A common refrain during the COVID-19 pandemic is, “I’m so tired.” After months of adjusted living and anxiety, people are understandably weary. Parents who haven’t had a break from their kids are worn out. Those trying to juggle working from home with homeschooling are stretched thin. Between concerns about health, finances, and isolation, everyone is feeling some level of additional stress during this unusual time, and that’s tiring. We all could use a good, long nap — or better yet, a vacation.
But while a break would be nice, most people — except those who are actually sick with COVID-19 or other illnesses...
Source: Harvard Health Blog - October 21, 2020 Category: Consumer Health News Authors: Jennifer Crystal, MFA Tags: Autoimmune diseases Fatigue Source Type: blogs
The tragedy of the post-COVID “ long haulers ”
Suppose you are suddenly are stricken with COVID-19. You become very ill for several weeks. On awakening every morning, you wonder if this day might be your last.
And then you begin to turn the corner. Every day your worst symptoms — the fever, the terrible cough, the breathlessness — get a little better. You are winning, beating a life-threatening disease, and you no longer wonder if each day might be your last. In another week or two, you’ll be your old self.
But weeks pass, and while the worst symptoms are gone, you’re not your old self — not even close. You can’t meet your responsibilities at home or at wor...
Source: Harvard Health Blog - October 15, 2020 Category: Consumer Health News Authors: Anthony Komaroff, MD Tags: Brain and cognitive health Coronavirus and COVID-19 Fatigue Source Type: blogs
Trial By Error: How Professor Lubet ’ s Nightmare Began …
By David Tuller, DrPH A few years ago, my friend and colleague Steven Lubet, a law professor and scholar at Northwestern University, wrote the following account of the start of his struggle with what was then largely called chronic fatigue syndrome. While his story does not directly relate to current events, Steve’s frustrations in his […] (Source: virology blog)
Source: virology blog - October 14, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized lubet Source Type: blogs
Fight Aging! Newsletter, September 28th 2020
In conclusion, it remains unclear if brain-specific regional and temporal changes occur in the expression of the different APP variants during AD progression. Since APP is also found in blood cells, assessing the changes in APP mRNA expression in peripheral blood cells from AD patients has been considering an alternative. However, again the quantification of APP mRNA in peripheral blood cells has generated controversial results.
Brain APP protein has been analyzed in only a few studies, probably as it is difficult to interpret the complex pattern of APP variants and fragments. We previously characterized the soluabl...
Source: Fight Aging! - September 27, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Reviewing the Clinical Evidence for NAD+ Upregulation
I recently collaborated on a review paper covering the history of clinical work on upregulation of nicotinamide adenine dinucleotide (NAD) as an approach to therapy. This is of interest to the aging research community because NAD is important to mitochondrial function. NAD levels diminish with age, alongside a loss of mitochondrial function that is known to contribute to the onset and progression of many age-related conditions. Animal studies and a few clinical trials have indicated that increased NAD levels may improve, for example, cardiovascular function in older individuals, as a result of improved mitochondrial functi...
Source: Fight Aging! - September 22, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Trial By Error: More CBT Research from Sir Simon and Professor Chalder
By David Tuller, DrPH (*Thanks to the the very informed discussion–and discussants–on the Science For ME forum for alerting me to this study and its many problems!) In 2011, Professor Trudie Chalder declared at a press conference for the high-profile PACE trial that twice as many chronic fatigue syndrome patients who received cognitive behavior therapy […] (Source: virology blog)
Source: virology blog - August 12, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized CBT chalder PACE Wessely Source Type: blogs
What is ME – Myalgic Encephalomyelitis?
Myalgic Encephalomyelitis, also known as Chronic Fatigue Syndrome, is a little-understood, female-biased [1] illness. It is estimated that up to 90% of people with the condition go diagnosed [2] and about 25% of sufferers are severely ill [3]. In recognition of the profound physical and psychological impact this disease has on its victims, August 8th has been designated as a Severe ME Awareness Day.
What is Myalgic Encephalomyelitis (ME)?
The disease is best known for a state of extreme and unremitting fatigue. A range of additional symptoms may suggest the presence of an infectious disease: myalgia, nausea, cogniti...
Source: GIDEON blog - August 8, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Identify News Source Type: blogs
Trial By Error: Columbia Experts Urge BMJ to Retract Not-Fully-Reviewed Study
By David Tuller, DrPH On Thursday, Professors Vincent Racaniello and Mady Hornig, both from Columbia University, wrote to BMJ’s research integrity coordinator. I have been corresponding with BMJ, and specifically the research integrity coordinator, about the Norwegian study of cognitive behavior therapy combined with music therapy as a treatment for chronic fatigue in adolescents after […] (Source: virology blog)
Source: virology blog - July 25, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized BMJ CBT mononucleosis music therapy norway Source Type: blogs
Trial By Error: Columbia Experts Urge BMJ to Retract Problem-Plagued Study
By David Tuller, DrPH On Thursday, Professors Vincent Racaniello and Mady Hornig, both from Columbia University, wrote to BMJ’s research integrity coordinator. I have been corresponding with BMJ, and specifically the research integrity coordinator, about the Norwegian study of cognitive behavior therapy combined with music therapy as a treatment for chronic fatigue in adolescents after […] (Source: virology blog)
Source: virology blog - July 25, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized BMJ CBT mononucleosis music therapy norway Source Type: blogs
