BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-MH-23-290 from the NIH Guide for Grants and Contracts. This is a reissue of RFA-MH-21-175 to comply with DMSP policy. The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. Plans for validating the utility of the tool/technology will be an essenti...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 8, 2023 Category: Research Source Type: funding

Center without Walls for PET Ligand Development for Alzheimer's disease-related dementias (ADRDs) (U19 - Clinical Trial Optional)
Funding Opportunity RFA-NS-24-011 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) supports the development of PET radioligands that identify proteinopathies or pathological processes associated with the human biology of Alzheimer's disease related dementias (ADRDs). Activities supported under this FOA include, but are not limited to the in vitro screening of existing ligands against human ADRD brain tissue, medicinal chemistry support for development of new compounds and improvement of existing ligand specificity and selectivity, initial screening of ligands in appropriate animal...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 3, 2023 Category: Research Source Type: funding

Limited Competition: Molecular Transducers of Physical Activity Chemical Analysis Sites (U24 Clinical Trial Not Allowed)
Funding Opportunity RFA-RM-23-021 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to invite applications for Chemical Analysis Sites to serve as part of the Molecular Transducers of Physical Activity Consortium (MoTrPAC; http://commonfund.nih.gov/MolecularTransducers). This is a limited competition FOA and open only to the previously funded grantees of MoTrPAC Chemical Analysis sites through RFA-RM-15-010 and RFA-RM-15-011. Awards made through this FOA will support participation of grantees in the MoTrPAC consortium activities and the continuation of the analysis of tissues collected by the MoTrP...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 2, 2023 Category: Research Source Type: funding

Limited Competition: Molecular Transducers of Physical Activity Bioinformatics Center (U24 Clinical Trial Not Allowed)
Funding Opportunity RFA-RM-23-020 from the NIH Guide for Grants and Contracts. This limited competition FOA invites applications for a Bioinformatics Center to serve as part of the Molecular Transducers of Physical Activity Consortium (MoTrPAC; http://commonfund.nih.gov/MolecularTransducers). The overall goals of the Bioinformatics Center are to provide a database and associated tools for storage and integration of clinical physiological and metabolic data along with multiple types of chemical analysis data derived through metabolomics, proteomics, genomics, transcriptomics, or similar technologies. The Bioinformatics C...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 2, 2023 Category: Research Source Type: funding

Update on Improving Fellowship Review: A Request for Information
This blog has been co-authored with Noni Byrnes, Director, Center for Scientific Review, NIH. Originally posted on the Review Matters blog. Mike Lauer, Deputy Director for Extramural Research, NIH Noni Byrnes, Ph.D., Director of NIH Center for Scientific Review NIH is recommending changes to the peer review of Ruth L. Kirschstein National Research Service Award (NRSA) fellowship applications by restructuring the review criteria and modifying some sections of the PHS Fellowship Supplemental Form that are specific to NRSAs. The goal of this effort is to facilitate the mission of NRSA fellowship peer review – to iden...
Source: NIH Extramural Nexus - April 25, 2023 Category: Research Authors: Mike Lauer Tags: blog Open Mike fellowship NRSA request for information Request For Information (RFI) Review Source Type: funding

Notice to Expire RFA-RM-23-009 "Limited Competition: Molecular Transducers of Physical Activity Chemical Analysis Sites (U24 Clinical Trial Not Allowed)"
Notice NOT-RM-23-012 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 21, 2023 Category: Research Source Type: funding

Limited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional)
Funding Opportunity RFA-ES-23-001 from the NIH Guide for Grants and Contracts. The National Institute of Environmental Health Sciences (NIEHS) is announcing the continuation of the Superfund Hazardous Substance Research and Training Program, referred to as Superfund Research Program (SRP) Centers. SRP Center grants will support problem-based, solution-oriented research Centers that consist of multiple, integrated projects representing both the biomedical and environmental science and engineering disciplines; as well as cores tasked with administrative (which includes research translation), data management and analysis, ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 17, 2023 Category: Research Source Type: funding

Assay Development and Screening for Discovery of Validated Chemical Hits for Brain Disorders (R01 Clinical Trial Not Allowed)
The objective of this funding opportunity announcement (FOA) is to stimulate research in 1) discovery and development of novel, small molecules for their potential use in studying disease treatment relevant to psychiatric disorders; and 2) to generate new insight into the biology of relevant diseases and processes that have yet to be validated as important drug targets. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 17, 2023 Category: Research Source Type: funding

Centers for Chemical Innovation (CCI) Phase I Awards and New Phase II Centers
Available Formats: HTML: https://www.nsf.gov/pubs/2023/nsf23575/nsf23575.htm?WT.mc_id=USNSF_25&WT.mc_ev=clickPDF: https://www.nsf.gov/pubs/2023/nsf23575/nsf23575.pdf?WT.mc_id=USNSF_25&WT.mc_ev=clickDocument Number: nsf23575Public Comment: This is an NSF Program Announcements and Information item. (Source: NSF Program Announcements and Information)
Source: NSF Program Announcements and Information - April 7, 2023 Category: Science Source Type: funding

Notice of Intent to Publish a Funding Opportunity Announcement for Next Generation Chemistry Centers for Fusion Oncoproteins (UM1 Clinical Trial Not Allowed)
Notice NOT-CA-23-058 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 4, 2023 Category: Research Source Type: funding

Dear Colleague: Planning Proposals for Partnerships for Research and Education in Chemistry (PREC) Program
Available Formats: HTML: https://www.nsf.gov/pubs/2023/nsf23084/nsf23084.jsp?WT.mc_id=USNSF_25&WT.mc_ev=clickPDF: https://www.nsf.gov/pubs/2023/nsf23084/nsf23084.pdf?WT.mc_id=USNSF_25&WT.mc_ev=clickDocument Number: nsf23084Public Comment: This is an NSF Program Announcements and Information item. (Source: NSF Program Announcements and Information)
Source: NSF Program Announcements and Information - April 3, 2023 Category: Science Source Type: funding

CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Translational Exploratory/Developmental Research Projects (R21 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-139 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) supports translational exploratory/developmental research that directly advances the discovery of novel treatment strategies, i.e., medical countermeasures (MCMs), that address serious morbidity and mortality after acute exposure to highly toxic chemical threats. Chemical threats are toxic compounds that could be used in a terrorist attack or accidentally released from industrial production, storage, or shipping. They include traditional chemical warfare agents, toxic industrial chemicals, pesticides, ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 22, 2023 Category: Research Source Type: funding

Limited Competition: Molecular Transducers of Physical Activity Bioinformatics Center (U24 Clinical Trial Not Allowed)
Funding Opportunity RFA-RM-23-008 from the NIH Guide for Grants and Contracts. This limited competition FOA invites applications for a Bioinformatics Center to serve as part of the Molecular Transducers of Physical Activity Consortium (MoTrPAC; http://commonfund.nih.gov/MolecularTransducers). The overall goals of the Bioinformatics Center are to provide a database and associated tools for storage and integration of clinical physiological and metabolic data along with multiple types of chemical analysis data derived through metabolomics, proteomics, genomics, transcriptomics, or similar technologies. The Bioinformatics C...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 22, 2023 Category: Research Source Type: funding

Limited Competition: Molecular Transducers of Physical Activity Chemical Analysis Sites (U24 Clinical Trial Not Allowed)
Funding Opportunity RFA-RM-23-009 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to invite applications for Chemical Analysis Sites to serve as part of the Molecular Transducers of Physical Activity Consortium (MoTrPAC; http://commonfund.nih.gov/MolecularTransducers). This is a limited competition FOA and open only to the previously funded grantees of MoTrPAC Chemical Analysis sites through RFA-RM-15-010 and RFA-RM-15-011. Awards made through this FOA will support participation of grantees in the MoTrPAC consortium activities and the continuation of the analysis of tissues collected by the MoTrP...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 22, 2023 Category: Research Source Type: funding

Novel Approaches for Developmental Neurotoxicity Testing (R43/R44 Clinical Trial Not Allowed)
Funding Opportunity RFA-ES-23-008 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) supports Phase I (R43), Phase II (R44), Direct to Phase II (R44), and Fast Track (R44) Small Business Innovative Research (SBIR) grant applications from small businesses concerns (SBCs) to develop resources, new methods, and approaches that can be applied in testing strategies to help understand the role of environmental chemicals in the etiology of the neurodevelopmental disorders. There is a need for novel and innovative approaches including New Approach Methodologies (NAMs) that can provide effecti...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 21, 2023 Category: Research Source Type: funding