Furofuran lignan glucosides from the leaves of Vitex negundo var. cannabifolia.
Abstract
Two new furofuran lignan glucosides, cannabilignin (1) and isocannabilignin (2), together with four known compounds (3-6), were isolated from the leaves of Vitex negundo var. cannabifolia. The structures of the isolates were elucidated by analysis of spectroscopic data. Compound 3 exhibited weak inhibition of nitric oxide production in lipopolysaccharide-stimulated BV-2 microglial cells with IC50 value of 69.1 ± 5.8 μM.
PMID: 27830592 [PubMed - as supplied by publisher] (Source: Natural Product Research)
Source: Natural Product Research - November 9, 2016 Category: Biochemistry Authors: Li YT, Li MM, Sun J, Zhu ZX, Song YL, Pang DR, Zheng J, Zhao YF, Tu PF, Li J Tags: Nat Prod Res Source Type: research
Biotechnological advances in Vitex species, and future perspectives
Publication date: Available online 5 October 2016 Source:Journal of Genetic Engineering and Biotechnology Author(s): Jaime A. Teixeira da Silva, Mafatlal M. Kher, M. Nataraj Vitex is a large genus consisting of 230 species of trees and shrubs with multiple (ornamental, ethnobotanic and pharmacological) uses. Despite this, micropropagation has only been used to effectively propagate and preserve germplasm a limited number (six) of Vitex species (V. agnus-castus, V. doniana, V. glabrata, V. negundo, V. rotundifolia, V. trifolia). This review on Vitex provides details of published micropropagation protocols and perspecti...
Source: Journal of Genetic Engineering and Biotechnology - October 5, 2016 Category: Biotechnology Source Type: research
Botanicals and Their Bioactive Phytochemicals for Women's Health.
Abstract
Botanical dietary supplements are increasingly popular for women's health, particularly for older women. The specific botanicals women take vary as a function of age. Younger women will use botanicals for urinary tract infections, especially Vaccinium macrocarpon (cranberry), where there is evidence for efficacy. Botanical dietary supplements for premenstrual syndrome (PMS) are less commonly used, and rigorous clinical trials have not been done. Some examples include Vitex agnus-castus (chasteberry), Angelica sinensis (dong quai), Viburnum opulus/prunifolium (cramp bark and black haw), and Zingibe...
Source: Pharmacological Reviews - September 30, 2016 Category: Drugs & Pharmacology Authors: Dietz BM, Hajirahimkhan A, Dunlap TL, Bolton JL Tags: Pharmacol Rev Source Type: research
Preliminary studies on the anti-ulcer potentials of Vitex doniana crude extracts on experimental rat model of ethanol induced gastric ulcer
Conclusions Crude extracts of Vitex doniana possess antiulcer properties against ethanol induced gastric ulcers. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - September 9, 2016 Category: Tropical Medicine Source Type: research
Molecules, Vol. 21, Pages 1179: A Review on the Terpenes from Genus Vitex
The genus Vitex, which belongs to the Verbenaceae family, includes approximately 250 species. Some species of the genus Vitex have traditionally been used for the treatment of headaches, ophthalmodynia, coughs, asthma, premenopausal syndrome, etc. Chemical investigations indicate that the characteristic constituents of the genus Vitex are terpenes, and 210 of these compounds, including monoterpenoids, sesquiterpenoids, diterpenoids and triterpenoids, have been obtained from 12 species. Pharmacological studies had shown that these terpenes possess anti-inflammatory, antitumor, antibacterial, antioxidant activities, and so o...
Source: Molecules - September 5, 2016 Category: Chemistry Authors: Jin-Long Yao Shi-Ming Fang Rui Liu Mahmood Oppong Er-Wei Liu Guan-Wei Fan Han Zhang Tags: Review Source Type: research
