Tropical Travel Trouble 007 Mega Malaria Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 007 When you think tropical medicine, malaria has to be near the top. It can be fairly complex and fortunately treatment has become a lot simpler. This post is designed to walk you through the basic principals with links to more in depth teaching if your niche is travel medicine, laboratory diagnostics or management of severe or cerebral malaria. If you stubbled on this post while drinking a cup of tea or sitting on the throne and want a few basi...
Source: Life in the Fast Lane - April 5, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Clinical Cases Tropical Medicine malaria Plasmodium plasmodium falciparum plasmodium knowles plasmodium malariae plasmodium ovale plasmodium vivax Source Type: blogs

Expert advice on how to quit smoking
Okay, everyone knows smoking is bad for you, the number one cause of preventable death in the US and the world, a direct cause of lung and heart disease and cancer… et cetera. So let’s get right down to the nitty-gritty: quitting smoking is tough. What can people do to quit? To answer this question, I spoke with my colleague Nancy Rigotti, MD. Dr. Rigotti is director of the Massachusetts General Hospital Tobacco Research and Treatment Center. She has extensively researched nicotine and tobacco, evaluated public policies on tobacco, contributed to US Surgeon General’s Reports, and authored clinical guidelines on smoki...
Source: Harvard Health Blog - February 8, 2018 Category: Consumer Health News Authors: Monique Tello, MD, MPH Tags: Health Heart Health Lung disease Prevention Smoking cessation Source Type: blogs

Looking under the hood: How brain science informs addiction treatment
As a neuroscientist I have been trained to think in a certain way, almost like a car mechanic, who “looks under the hood” at the brains of laboratory rats exposed to drugs. If we can figure out exactly which genes, proteins, brain regions, and neural connections go awry in substance use disorders (SUDs), we can fix those “broken” parts in the brain and design better long-term approaches to addiction treatment. While there is great promise in this approach, it’s not so easy to get under the hood of people who desperately need help with a SUD. It’s very different from working with lab rats. And it can take a long...
Source: Harvard Health Blog - November 15, 2017 Category: Consumer Health News Authors: Elena H. Chartoff, PhD Tags: Addiction Behavioral Health Brain and cognitive health substance use disorders (SUDs) Source Type: blogs

Top 25 Psychiatric Medications for 2016
Most people understand that the role of psychiatric medications is to help alleviate the symptoms associated with different types of mental disorders, such as depression, bipolar disorder, ADHD, schizophrenia, anxiety, and more. Psychiatric medications are an important part of a comprehensive treatment plan for effectively treating people who have a mental health concern or mental illness. It’s good to know what drugs are being most-often prescribed for mental disorders in the U.S. These are the top 25 psychiatric medications by number of U.S. prescriptions dispensed in 2016, according to QuintilesIMS, a global infor...
Source: World of Psychology - October 12, 2017 Category: Psychiatry & Psychology Authors: John M. Grohol, Psy.D. Tags: General Medications Psychiatry Treatment medications for mental illness Psychiatric Drugs Psychiatric Medications psychiatric meds top psychiatric medications Source Type: blogs

Hating on Antipsychotics: Are We Going Too Far?
(Source: The Carlat Psychiatry Blog)
Source: The Carlat Psychiatry Blog - September 12, 2017 Category: Psychiatry Tags: antipsychotics aripiprazole bupropion FDA Research Source Type: blogs

Research and Reviews in the Fastlane 183
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Welcome to the  183rd edition of Research and Reviews in the Fastlane. R&R in the Fastlane is a free resource that harnesses the power of social media to allow some of the best and brightest emergency medicine and critical care clinicians from all over the world tell us what they think is worth reading from the published literature. This edition contains  5 recommended reads. The R&R Editorial Team includes Jeremy Fried, Nudrat Rashid, Justin Morgenstern and Ch...
Source: Life in the Fast Lane - May 24, 2017 Category: Emergency Medicine Authors: Jeremy Fried Tags: Airway Emergency Medicine R&R in the FASTLANE Toxicology and Toxinology EBM Education literature recommendations research and reviews Source Type: blogs

Research and Reviews in the Fastlane 180
This article reviews lavage cases called in to a state poison center and finds that while numbers are down, many of the ones performed were inappropriate. Bottom line, better education needs to be done to stress when and where it’s useful. Ingestions within 60 minutes of presentation of enough drug to have a serious toxic effect and where there’s no available antidote should prompt consideration for lavage in conjunction with a toxicologist when possible. Recommended by: Anand Swaminathan Toxicology Nelson CJ et al. Morbidity and mortality associated with medications used in the treatment of depression: an ...
Source: Life in the Fast Lane - May 4, 2017 Category: Emergency Medicine Authors: Nudrat Rashid Tags: Education General Surgery Infectious Disease Intensive Care Microbiology R&R in the FASTLANE Resuscitation Social Media Toxicology Toxicology and Toxinology critical care Emergency Medicine literature recommendations research a Source Type: blogs

Medications that Increase the Risks of Falling
Falls are the leading cause of both fatal and non-fatal injuries for adults 65 and older, and research suggests that those taking four or more medications are at an even greater risk than those who don ’t.ByAlzheimer's Reading RoomWhat ’s the Difference Between Alzheimer’s and DementiaHow to Test Your Memory for Alzheimer's and DementiaHow to Get Answers To Your Questions About Alzheimer's and Dementia“Falls are the leading cause of both fatal and non-fatal injuries for adults 65 and older, and research suggests that those taking four or more medications are at an even greater risk than those who don’t – perhap...
Source: Alzheimer's Reading Room, The - February 1, 2017 Category: Neurology Tags: alzheimer's care care of dementia patients dementia care health help alzheimer's help with dementia care medications falls Prescription Medications Risks risk of falling senior care Source Type: blogs

Dementia Care, Which Drugs Increase the Risk of Falling
Medications can increase the risk of falls and falling; and, are a major cause of injuries and death in older adults.By Bob DeMarcoAlzheimer's Reading RoomDuring the entire 8 and a half years, 3,112 days, that I was taking care of my mother, I worried about her falling.Falls can result in hip injuries, head injuries, or something worse.If you loved one is falling, or complaining of "dizziness" check out the list of medications below; and then, consult with your personal care doctor.Problems with Balance, Walking, Falling an Early Sign of DementiaThe drugs older people take can make them more susceptible to falling.Research...
Source: Alzheimer's Reading Room, The - September 7, 2016 Category: Neurology Tags: alzheimer's care Alzheimer's Dementia dementia care dementia falls dementia help for caregivers family caregiving help alzheimer's help with dementia care memory care searches related to falling Source Type: blogs

Orexigen Terminates Another Cardiovascular Outcomes Trial
Updated–In a further sign of the chaos surrounding its weight loss drug Contrave, Orexigen has again terminated an FDA-mandated cardiovascular outcomes trial with the drug. Following a year of controversy (see below) Orexigen last month assumed sole control of Contrave (the combination of naltrexone and bupropion) from its former partner, Takeda. The company has now terminated enrollment...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - April 13, 2016 Category: Cardiology Authors: Larry Husten Tags: Uncategorized Source Type: blogs

Controversial, Ill-Fated Obesity Drug Trial Published In JAMA
The final– but now largely useless– results of the cardiovascular safety trial of the obesity drug Contrave have now been published in JAMA, one year after the trial’s dramatic and scandalous crash and burn. By way of background: Contrave is a combination of naltrexone and bupropion marketed as a weight loss drug by Orexigen and...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - March 8, 2016 Category: Cardiology Authors: Larry Husten Tags: People, Places & Events Policy & Ethics Prevention, Epidemiology & Outcomes Contrave CVOT LIGHT Study Nissen obesity Orexigen patent application Source Type: blogs

LITFL Review 219
Welcome to the 218th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chuck of FOAM. The Most Fair Dinkum Ripper Beauts of the Week Is enhanced cardiopulmonary resuscitation (ECPR) a step too far? Listen to this great debate between two heavyweights from SMACC Chicago. [SO]   The Best of #FOAMed Emergency Medicine Anna Pickens puts together a great 5 minute video on th...
Source: Life in the Fast Lane - February 15, 2016 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review Source Type: blogs

DM / DNB Cardiology Entrance Mock Test 13
In this study, cangrelor was discontinued 1-6 hours prior to surgery, while aspirin was continued throughout the perioperative period. Bridging with cangrelor did not increase major bleeds prior to surgery, though minor bleeds, mostly ecchymosis at venipuncture site, was higher. P2Y12 assay documented sufficient platelet inhibition corresponding to levels required for anti thrombotic effect [1]. Cangrelor is awaiting approval and more large scale trials regarding the use of bridging are needed. Reference 1. Angiolillo DJ et al; BRIDGE Investigators. Bridging antiplatelet therapy with cangrelor in patients undergoing ...
Source: Cardiophile MD - February 7, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs

DM / DNB Cardiology Entrance Mock Test 5
Please wait while the activity loads. If this activity does not load, try refreshing your browser. Also, this page requires javascript. Please visit using a browser with javascript enabled. If loading fails, click here to try again Click on the 'Start' button to begin the mock test. After answering all questions, click on the 'Get Results' button to display your score and the explanations. There is no time limit for this mock test. Start Congratulations - you have completed DM / DNB Cardiology Entrance Mock Test 5. You scored %%SCORE%% out of %%TOTAL%%. Your performance...
Source: Cardiophile MD - January 20, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Featured Source Type: blogs