Stimulant/Naltrexone for Weight
I've had some patients that benefitted from bupropion/naltrexone for weight loss. I got to wondering about my ADHD patients that are on methylphenidate or amphetamine (but not bupropion) if adding naltrexone to their regimen would be helpful for weight loss. Does anyone have experience with, or thoughts about, this? (Source: Student Doctor Network)
Source: Student Doctor Network - December 18, 2023 Category: Universities & Medical Training Authors: aim-agm Tags: Psychiatry Source Type: forums

Weird case. Treatment Resistant Depression but after a snake bite
Got a patient that was already seen by a great clinician and she couldn't get this patient better. Was tried on all the conventional meds. A few SSRIs, SNRIs, Lamotrigine, Lithium, atypical antipsychotics (and yes the better ones for depression such as Aripiprazole, Cariprazine) , Bupropion, augmentation agents such as Buspirone, Auvelity, Esketamine, TMS (not ECT...yet). After several meetings she finally said something that hit me like a ton of bricks. She told me she never had mental... Read more (Source: Student Doctor Network)
Source: Student Doctor Network - October 11, 2023 Category: Universities & Medical Training Authors: whopper Tags: Psychiatry Source Type: forums

Bupropion and adult ADHD
I have a few adult patients in my practice with ADHD: I try to be very thougthful when giving this diagnosis, often interviewing other family members, more than 1 visit, standarized tests and such. These patients often have comorbid anxiety or depression, and when that is the case, I usually choose bupropion to try and treat more than 1 condition with just 1 drug. I've read the literature (Comparative efficacy and tolerability of medications for attention-deficit hyperactivity disorder in... Read more (Source: Student Doctor Network)
Source: Student Doctor Network - August 11, 2023 Category: Universities & Medical Training Authors: thelastpsych Tags: Psychiatry Source Type: forums

Long term use of antidepressants/bupropion
I am about to enter psychiatry residency so I still don't know much about the practice of psychiatry. I was wondering if there is any disadvantages of long term (more than 5+ years) administration of antidepressants such as bupropion. Should we seek to taper off the antidepressants if the psychosocial factors have been signifcantly improved in the last few years (and the patient has been feeling and functioning well) -- or should we choose to continue if the patient is doing well without... Read more (Source: Student Doctor Network)
Source: Student Doctor Network - April 7, 2023 Category: Universities & Medical Training Authors: phosphorylation414 Tags: Psychiatry Source Type: forums

What's the deal with "Auvelity"? (new NMDA receptor antagonist)
Got a notification that some biotech stock shot up about 35% today. Turns out that company just got FDA approval for "auvelity" and is marketing it as the greatest thing to come out for depression treatment since SSRIs. Looking into it the chemical formulation seems to be "dextromethorphan HBr -bupropion HCl", and it has been challenging finding peer reviewed articles about how well it really works. Perhaps I'm just too dumb to understand the pharmacology behind it, but isn't this... Read more (Source: Student Doctor Network)
Source: Student Doctor Network - August 23, 2022 Category: Universities & Medical Training Authors: Monocles Tags: Psychiatry Source Type: forums

Anorgasmia Treatments?
Looking for some input from the hive mind here. 33yo with schizophrenia. Had him on inpt for about 4 months before he was finally stabilised on Abilify Maintena 400mg and olanzapine 10mg. But he’s had Anorgasmia since being on the meds. Not sure which one did it as he came to me on both. No erectile difficulties, he just can’t finish. I tried bupropion and mirtazapine, no effect. Right now I’ve left him on trazodone 50mg qhs and amantadine 100mg BID (amantadine to counteract D2 blockade... Read more (Source: Student Doctor Network)
Source: Student Doctor Network - April 11, 2022 Category: Universities & Medical Training Authors: vanfanal Tags: Psychiatry Source Type: forums

Bupropion contraindications
Hello all, I am wondering, how strict are you with the FDA contraindications of bupropion and how would you handle the following situation? I tend to draw the line at not prescribing to people with an active restrictive or purging type eating disorder, as well as known seizure history. Now, what if you had a patient on bupropion with active anorexia and a history of seizure, whom you inherited from a colleague. You took them off bupropion and they are doing poorly. There are other options... Read more (Source: Student Doctor Network)
Source: Student Doctor Network - December 30, 2021 Category: Universities & Medical Training Authors: throwaway2222 Tags: Psychiatry Source Type: forums

aplenzin (bupropion hydrobromide) vs bupropion hcl
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Source: Student Doctor Network - January 18, 2017 Category: Universities & Medical Training Authors: ronkoshy Source Type: forums

sexual dysfunction
How do you guys typically handle the common complaint of sexual dysfunction with antidepressants? I just wanted to see what other ideas are out there. I know antidepressants less prone to causing this are mirtazapine and bupropion. I've heard of adding bupropion to the regimen and cyproheptadine. I've also heard of just adding some prn Viagra for the men who specifically complain of erectile dysfunction. Any other thoughts? Also, how would you guys typically rank how notorious certain... sexual dysfunction (Source: Student Doctor Network)
Source: Student Doctor Network - November 9, 2016 Category: Universities & Medical Training Authors: randomdoc1 Source Type: forums