No more PMRT for cN1 ypN0 breast cancer?
De-escalation of radiotherapy after primary chemotherapy in cT1–2N1 breast cancer (RAPCHEM; BOOG 2010–03): 5-year follow-up results of a Dutch, prospective, registry study
BackgroundPrimary chemotherapy in breast cancer poses a dilemma with regard to adjuvant locoregional radiotherapy, as guidelines for locoregional radiotherapy were originally based on pathology results of primary surgery. We aimed to evaluate the oncological safety of de-escalated locoregional...
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Source: Student Doctor Network - September 3, 2022 Category: Universities & Medical Training Authors: TheWallnerus Tags: Radiation Oncology Source Type: forums
ASCO 2022 abstracts
are out. Here are some interesting radonc picks:
https://meetings.asco.org/abstracts-presentations/206928
SBRT & surgery for oligometastastic breast cancer does not seem to work.
https://meetings.asco.org/abstracts-presentations/207129
Perhaps new s.o.c. for mucositis prevention in H&N cancer
https://meetings.asco.org/abstracts-presentations/211847
PSMA-PET-CT changing management in almost half of the patients receiving salvage RT for biochemical...
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Source: Student Doctor Network - May 27, 2022 Category: Universities & Medical Training Authors: Palex80 Tags: Radiation Oncology Source Type: forums
Breast cancer; prior lymphoma radiation
I have a case of an otherwise health 50 ish year old with a T1 luminal A breast cancer. MRI breast staging confirms T1N0M0.
Prior radiation for Hodgkin's at age 15.
I know the boards answer here, but it's so tempting to consider this for APBI if she desires BCS. I think cosmestically, etc it'll be fine. I guess my biggest worry is just lifetime risk of further breast cancers.
So I'm leaning mastectomy(ies) here.
Thoughts? (Source: Student Doctor Network)
Source: Student Doctor Network - May 12, 2022 Category: Universities & Medical Training Authors: BobbyHeenan Tags: Radiation Oncology Source Type: forums
is PMRT needed for this patient?
54 years old patient, PS0, no medical comorbidities (obese), no family history of breast cancer
underwent a MRM + LND for left Breast invasive Carcinoma
Pathology showed:
- T4cm, 0Ln/18 dissected pT2N0, free margins
- G3, LVI ++,
- ER 50%, PR 10%, Her2 neg
- Ki 30% (Source: Student Doctor Network)
Source: Student Doctor Network - May 10, 2022 Category: Universities & Medical Training Authors: Kroll2013 Tags: Radiation Oncology Source Type: forums
Rad Onc in The Lancet Oncology
Primary radiotherapy and deep inferior epigastric perforator flap reconstruction for patients with breast cancer (PRADA): a multicentre, prospective, non-randomised, feasibility study
There are a number of trials in this space now looking preoperative vs. postoperative radiation. I think this is the foot in the door to definitive radiation for selected pts. If you can treat positive nodes definitively with RT, you probably can do the same for (some) primaries (Source: Student Doctor Network)
Source: Student Doctor Network - April 12, 2022 Category: Universities & Medical Training Authors: radiation Tags: Radiation Oncology Source Type: forums
Breast is the worst: another, another, ANOTHER case!
Hi, I have one. 36 F, triple positive breast cancer with essentially no response to NA-TCHP. T1c up front and out back, node negative. She had a suspicious axillary node on MRI, biopsy negative and 3 nodes removed at the time of surgery, no treatment effect seen. Will be getting TDM-1. Planning whole breast + boost, how many would be a little generous in the axilla given the poor response to chemo? That would be my inclination. (Source: Student Doctor Network)
Source: Student Doctor Network - March 25, 2022 Category: Universities & Medical Training Authors: RO28 Tags: Radiation Oncology Source Type: forums
Re: Evaluation of pathological complete response as surrogate endpoint in neoadjuvant randomised clinical trials of early stage breast cancer: systematic review and meta-analysis
(Source: BMJ Comments)
Source: BMJ Comments - December 29, 2021 Category: General Medicine Source Type: forums
Re: Remote, proactive, telephone based management of toxicity in outpatients during adjuvant or neoadjuvant chemotherapy for early stage breast cancer: pragmatic, cluster randomised trial
(Source: BMJ Comments)
Source: BMJ Comments - December 20, 2021 Category: General Medicine Source Type: forums
Update Letter for Family Illness?
Sadly, my fiance's mother was just diagnosed with metastatic breast cancer. Until this news, my fiance and I were up for moving anywhere in the US for medical school. Now, we are torn about moving too far from her mother in NJ. Thus far I haven't had any luck with NY/NJ/east coast schools. Can anyone advise if it would be appropriate and/or beneficial to send a brief update letter explaining this? I am scared that a letter would come across as a plea for pity, so I am leaning towards not...
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Source: Student Doctor Network - December 14, 2021 Category: Universities & Medical Training Authors: mwbrown3 Tags: Pre-Medical (MD) Source Type: forums
Truly PROSPER after breast cancer surgery in the 21st century with exercise AND technology
(Source: BMJ Comments)
Source: BMJ Comments - December 8, 2021 Category: General Medicine Source Type: forums
Re: Use of artificial intelligence for image analysis in breast cancer screening programmes: systematic review of test accuracy
(Source: BMJ Comments)
Source: BMJ Comments - October 11, 2021 Category: General Medicine Source Type: forums
SABCS boycott due to Texas Abortion Law
Call for a Move or Boycott of Big Texas Cancer Meeting
Oncologists are calling for this year's San Antonio Breast Cancer Symposium to be moved out of Texas in response to the state's new abortion law, and a boycott of in-person attendance if no move happens.
www.medscape.com
The funny thing is that they are not proposing a true boycott, just planning to attend on-line rather than in-person. That type of "protest" won't fly with ASTRO as there is no discount for attending online anyway so they get paid the same regardless. (Source: Student Doctor Network)
Source: Student Doctor Network - September 21, 2021 Category: Universities & Medical Training Authors: Gfunk6 Tags: Radiation Oncology Source Type: forums
Re: Effect of screening by clinical breast examination on breast cancer incidence and mortality after 20 years: prospective, cluster randomised controlled trial in Mumbai
(Source: BMJ Comments)
Source: BMJ Comments - July 5, 2021 Category: General Medicine Source Type: forums
Leptomeningeal Carcinomatosis
Case discussion time. Serious replies only please.
Imagine a hypothetical young woman, 35 years old with known breast cancer on systemic therapy, well controlled and limited systemic disease, comes in to ED with headaches that become controlled on dexamethasone. MRIs of brain and total spine show subtle faint streaks and dots consistent with leptomeningeal carcinomatosis in brain and cauda equina. Lumbar puncture is performed confirming cells in CSF on cytology. You are the rad onc...
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Source: Student Doctor Network - June 18, 2021 Category: Universities & Medical Training Authors: Neuronix Tags: Radiation Oncology Source Type: forums
