Bone Marrow Aspiration and Biopsy Blogs This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Doing Well
Still doing pretty well. I ' m currently taking Darzalex monthly, Pomalyst 2 mg daily (28 days of 28), and dexamethasone (Dex) 8 mg weekly. Monthly blood tests don ' t normally show any cause for concern, and I feel pretty good. Except lately calcium has been a bit high, and the doctors and I are paying some attention to that. Maybe a PET scan is due, or even a bone marrow biopsy, since my myeloma seems to have become "nonsecretory " (it may not secrete detectable immunoglobulin fragments). Ugh.I like a beer in the evening, but I skip that on Dex days and on the two days afterward. On infusion day I don ' t exercise a...
Source: Myeloma Hope - October 31, 2021 Category: Cancer & Oncology Tags: daratumumab Darzalex DEX dexamethasone pomalidomide Pomalyst Source Type: blogs

Bmb
I had my bone marrow biopsy yesterday (BMB in English, BOM in Italian). The easiest I’ve ever had. It wasn’t completely pain-free, which would have been, methinks, impossible (after all, the needle has to penetrate your pelvic bone!), and in fact a couple of times I felt what I can describe as painful shockwaves running down my right leg, but no, nothing unbearable. And the BMB was also over quickly, compared to my three others. After it was done, the nurse bandaged and iced me up and then asked me to turn over and lie on my back to apply pressure on the area. That was nice. My previous BMB doctors had simply s...
Source: Margaret's Corner - September 22, 2021 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll biopsia osteo-midollare BMB BOM bone marrow biopsy Source Type: blogs

The fun is over …
Sirmione, Lago di Garda Stefano and I had a lovely relaxing holiday in August. The first leg of our trip consisted of three days in the medieval town of Sirmione on the shores of one of Italy’s largest and prettiest lakes, the Lago di Garda. To be honest, though, I couldn’t wait to leave. It wasn’t the heat that got to me (after Florence, practically anything would have felt cool…), but rather the throngs of unmasked tourists surrounding us as we walked along the town’s narrow streets. I found that quite unsettling. True, you don’t have to wear a mask now when you’re out in the ope...
Source: Margaret's Corner - September 17, 2021 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll hip replacement surgery Lago di Braies Mantova Tre Cime di Lavaredo Source Type: blogs

Another Bone Marrow Biopsy
I had another bone marrow biopsy last month. My nephew took this picture of the samples being prepared for the lab. The dish near the top of the image looks like a tiny little crime scene. The post Another Bone Marrow Biopsy appeared first on Beth Morgan Multiple Myeloma Treatment Blog. (Source: beth's myeloma blog)
Source: beth's myeloma blog - August 31, 2021 Category: Cancer & Oncology Authors: Beth Tags: Bone Marrow Biopsy Myeloma Talquetamab Source Type: blogs

TAB ’ s July 2021 update
TAB wrote his update as a comment to the post I wrote about him back in 2012, but I decided that this update should be turned into a post, as follows… TAB’s Update 7/9/2021 Smoldering 20 years, progression 2 years, Velcade for 4 months = complete remission. My journey with IgA Lambda Multiple Myeloma has been a long one. At age 80 I am finally in complete remission. During the first 20 years I took only over the counter supplements which in my opinion kept the beast at bay. I plotted the results of my blood tests using Excel and relied on the trend lines to keep track of how I was doing. After a few years of supple...
Source: Margaret's Corner - July 19, 2021 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll Source Type: blogs

Fight Aging! Newsletter, June 28th 2021
In conclusion, in our prospective community-based study, aging-related biomarkers were associated with measures of subclinical atherosclerosis cross-sectionally and with all-cause mortality prospectively, supporting the concept that these biomarkers may reflect the aging process in community-dwelling adults. The Role of Aging Macrophages in Skin Inflammation https://www.fightaging.org/archives/2021/06/the-role-of-aging-macrophages-in-skin-inflammation/ The immune system is complex and ages in complex ways, pressed by the lifetime burden of infection and rising levels of molecular damage that trigger man...
Source: Fight Aging! - June 27, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Bone Marrow Biopsy
I had a bone marrow biopsy yesterday. It was supposed to be tomorrow, but it got moved up a few days so they can try to get me admitted on the 25th to start the trial. I hung out for a while afterwards to talk to the lab folks, and they answered all of my … The post Bone Marrow Biopsy first appeared on Beth Morgan Multiple Myeloma Treatment Blog. (Source: beth's myeloma blog)
Source: beth's myeloma blog - May 19, 2021 Category: Cancer & Oncology Authors: Beth Tags: Bone Marrow Biopsy Myeloma Source Type: blogs

Daratumumab, Pomalyst & Talquetamab Trial
I’ve signed consents and started testing for a new trial using daratumumab (dara), pomalyst (pom) & a new drug called talquetamab. The one thing I have left to do is the bone marrow biopsy, which will be done next Thursday. Here’s a link to the info about the trial. https://clinicaltrials.gov/ct2/show/NCT04108195 I’ve had another PET scan … The post Daratumumab, Pomalyst & Talquetamab Trial first appeared on Beth Morgan Multiple Myeloma Treatment Blog. (Source: beth's myeloma blog)
Source: beth's myeloma blog - May 16, 2021 Category: Cancer & Oncology Authors: Beth Tags: daratumumab Darzalex pomalidomide Pomalyst Talquetamab DARZALEX FASPRO® Darzalex® Source Type: blogs

Fight Aging! Newsletter, March 8th 2021
Conclusion Coupled with the animal data, and the existing human trial data for safety, the results here suggests that someone should run a formal, controlled trial of flagellin immunization in older people, 65 and over. The goal would be to see whether (a) this sort of outcome holds up in a larger group of people, and (b) there is a meaningful impact on chronic inflammation and other parameters of health that are known to be affected by the aging of the gut microbiome. The Role of Reactive Oxygen Species in Aging is Complex https://www.fightaging.org/archives/2021/03/the-role-of-reactive-oxygen-species-in-a...
Source: Fight Aging! - March 7, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, March 1st 2021
This study may have important implications for preventing cell senescence and aging-induced tendinopathy, as well as for the selection of novel therapeutic targets of chronic tendon diseases. Our results showed that the treatment of bleomycin, a DNA damaging agent, induced rat patellar TSC (PTSC) cellular senescence. The senescence was characterized by an increase in the senescence-associated β-galactosidase activity, as well as senescence-associated changes in cell morphology. On the other hand, rapamycin could extend lifespan in multiple species, including yeast, fruit flies, and mice, by decelerating DNA damage ...
Source: Fight Aging! - February 28, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

TNB-383B Phase I Trial
I recently enrolled in a clinical trial at Wake Forest Baptist Health. A phase I trial to test TeneoBio’s TNB-383B. Before this, I spent several months on carfilzomib, dex, and cyclophosphamide. Test results and bone marrow biopsy indicated I was relapsing. TNB-383B is a BCMA x CD3 T-cell engaging bispecifc antibody being studied in relapsed … The post TNB-383B Phase I Trial first appeared on Beth Morgan Multiple Myeloma Treatment Blog. (Source: beth's myeloma blog)
Source: beth's myeloma blog - November 24, 2020 Category: Cancer & Oncology Authors: Beth Tags: Myeloma Myeloma Treatment CRS cytoxan release syndrome TNB-383B Phase I Trial Wake Forest Baptist Health Source Type: blogs

Fight Aging! Newsletter, October 26th 2020
In conclusion, all NAFLD histological stages were associated with significantly increased overall mortality, and this risk increased progressively with worsening NAFLD histology. Most of this excess mortality was from extrahepatic cancer and cirrhosis, while in contrast, the contributions of cardiovascular disease and HCC were modest. BMP6 as a Target for Pro-Angiogenic Therapies https://www.fightaging.org/archives/2020/10/bmp6-as-a-target-for-pro-angiogenic-therapies/ Today's research materials are focused on the fine details of angiogenesis, the formation of new blood vessels, and point to BMP6 as a p...
Source: Fight Aging! - October 25, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, January 6th 2020
Conclusion A great deal of progress is being made in the matter of treating aging: in advocacy, in funding, in the research and development. It can never be enough, and it can never be fast enough, given the enormous cost in suffering and lost lives. The longevity industry is really only just getting started in the grand scheme of things: it looks vast to those of us who followed the slow, halting progress in aging research that was the state of things a decade or two ago. But it is still tiny compared to the rest of the medical industry, and it remains the case that there is a great deal of work yet to be done at all...
Source: Fight Aging! - January 5, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Look Back at 2019: Progress Towards the Treatment of Aging as a Medical Condition
Conclusion A great deal of progress is being made in the matter of treating aging: in advocacy, in funding, in the research and development. It can never be enough, and it can never be fast enough, given the enormous cost in suffering and lost lives. The longevity industry is really only just getting started in the grand scheme of things: it looks vast to those of us who followed the slow, halting progress in aging research that was the state of things a decade or two ago. But it is still tiny compared to the rest of the medical industry, and it remains the case that there is a great deal of work yet to be done at all...
Source: Fight Aging! - December 31, 2019 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

“ Chasing My Cure ” : A Book Review
By CHADI NABHAN, MD, MBA, FACP Have you thought about your own mortality? Who hasn’t, given the frequency of seeing death and grief depicted in the media or through real life encounters with friends, relatives, neighbors, or patients? These incidents trigger uncomfortable and sometimes uneasy thoughts of how we might personally deal with potential illness and disease. The same thoughts are soon displaced by the busyness of living. Despite dealing with the death of his mother from a brain tumor, we learn David Fajgenbaum was healthy, living life to its fullest, and a future doctor in the making. He may hav...
Source: The Health Care Blog - December 16, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Patients Physicians Book Review Chadi Nabhan Chasing My Cure Chasing My Cure book review David Fajgenbaum Mortality Outspoken Oncology Source Type: blogs