Beyond the First Year: Epidemiology and Management of Late-Onset Opportunistic Infections After Kidney Transplantation
Transpl Int. 2024 Feb 26;37:12065. doi: 10.3389/ti.2024.12065. eCollection 2024.ABSTRACTLate opportunistic infections (OI) occurring beyond the first year after kidney transplantation (KT) are poorly described and not targeted by prophylactic strategies. We performed a ten-year retrospective monocentric cohort study describing epidemiology, risk factors and impact of late OI occurring 1 year after KT. We included clinically symptomatic OI requiring treatment besides BK virus nephropathy. Control groups included early OI occurring in the first year after KT, and KT recipients without OI since KT and alive with a functional ...
Source: Herpes - March 12, 2024 Category: Infectious Diseases Authors: V Esnault L Hoisnard B Peiffer V Fihman S Fourati C Angebault C Champy S Gallien P Attias A Morel P Grimbert G Melica M Matignon Source Type: research

Beyond the First Year: Epidemiology and Management of Late-Onset Opportunistic Infections After Kidney Transplantation
Transpl Int. 2024 Feb 26;37:12065. doi: 10.3389/ti.2024.12065. eCollection 2024.ABSTRACTLate opportunistic infections (OI) occurring beyond the first year after kidney transplantation (KT) are poorly described and not targeted by prophylactic strategies. We performed a ten-year retrospective monocentric cohort study describing epidemiology, risk factors and impact of late OI occurring 1 year after KT. We included clinically symptomatic OI requiring treatment besides BK virus nephropathy. Control groups included early OI occurring in the first year after KT, and KT recipients without OI since KT and alive with a functional ...
Source: Herpes - March 12, 2024 Category: Infectious Diseases Authors: V Esnault L Hoisnard B Peiffer V Fihman S Fourati C Angebault C Champy S Gallien P Attias A Morel P Grimbert G Melica M Matignon Source Type: research

Etiology of Meningoencephalitis in children aged less than 5 years
CONCLUSION: We identified the etiological agents in 50/130 (38.5%) suspected ME cases in children less than 5 years of age, using molecular and ELISA-based diagnostic methods. The four most common pathogens detected were JEV, adenovirus, influenza virus, and dengue virus.PMID:38394398 | DOI:10.4103/ijpm.ijpm_60_23 (Source: Herpes)
Source: Herpes - February 23, 2024 Category: Infectious Diseases Authors: Vivek K Mishra Tanzeela Khan Amar Jeet Om Prakash None Chandrakanta Ashish K Srivastava Sangram Singh Neelam Pathak Amita Jain Source Type: research

Etiology of Meningoencephalitis in children aged less than 5 years
CONCLUSION: We identified the etiological agents in 50/130 (38.5%) suspected ME cases in children less than 5 years of age, using molecular and ELISA-based diagnostic methods. The four most common pathogens detected were JEV, adenovirus, influenza virus, and dengue virus.PMID:38394398 | DOI:10.4103/ijpm.ijpm_60_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Vivek K Mishra Tanzeela Khan Amar Jeet Om Prakash None Chandrakanta Ashish K Srivastava Sangram Singh Neelam Pathak Amita Jain Source Type: research

Etiology of Meningoencephalitis in children aged less than 5 years
CONCLUSION: We identified the etiological agents in 50/130 (38.5%) suspected ME cases in children less than 5 years of age, using molecular and ELISA-based diagnostic methods. The four most common pathogens detected were JEV, adenovirus, influenza virus, and dengue virus.PMID:38394398 | DOI:10.4103/ijpm.ijpm_60_23 (Source: Herpes)
Source: Herpes - February 23, 2024 Category: Infectious Diseases Authors: Vivek K Mishra Tanzeela Khan Amar Jeet Om Prakash None Chandrakanta Ashish K Srivastava Sangram Singh Neelam Pathak Amita Jain Source Type: research

Etiology of Meningoencephalitis in children aged less than 5 years
CONCLUSION: We identified the etiological agents in 50/130 (38.5%) suspected ME cases in children less than 5 years of age, using molecular and ELISA-based diagnostic methods. The four most common pathogens detected were JEV, adenovirus, influenza virus, and dengue virus.PMID:38394398 | DOI:10.4103/ijpm.ijpm_60_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Vivek K Mishra Tanzeela Khan Amar Jeet Om Prakash None Chandrakanta Ashish K Srivastava Sangram Singh Neelam Pathak Amita Jain Source Type: research

Etiology of Meningoencephalitis in children aged less than 5 years
CONCLUSION: We identified the etiological agents in 50/130 (38.5%) suspected ME cases in children less than 5 years of age, using molecular and ELISA-based diagnostic methods. The four most common pathogens detected were JEV, adenovirus, influenza virus, and dengue virus.PMID:38394398 | DOI:10.4103/ijpm.ijpm_60_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Vivek K Mishra Tanzeela Khan Amar Jeet Om Prakash None Chandrakanta Ashish K Srivastava Sangram Singh Neelam Pathak Amita Jain Source Type: research

Etiology of Meningoencephalitis in children aged less than 5 years
CONCLUSION: We identified the etiological agents in 50/130 (38.5%) suspected ME cases in children less than 5 years of age, using molecular and ELISA-based diagnostic methods. The four most common pathogens detected were JEV, adenovirus, influenza virus, and dengue virus.PMID:38394398 | DOI:10.4103/ijpm.ijpm_60_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Vivek K Mishra Tanzeela Khan Amar Jeet Om Prakash None Chandrakanta Ashish K Srivastava Sangram Singh Neelam Pathak Amita Jain Source Type: research

Etiology of Meningoencephalitis in children aged less than 5 years
CONCLUSION: We identified the etiological agents in 50/130 (38.5%) suspected ME cases in children less than 5 years of age, using molecular and ELISA-based diagnostic methods. The four most common pathogens detected were JEV, adenovirus, influenza virus, and dengue virus.PMID:38394398 | DOI:10.4103/ijpm.ijpm_60_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Vivek K Mishra Tanzeela Khan Amar Jeet Om Prakash None Chandrakanta Ashish K Srivastava Sangram Singh Neelam Pathak Amita Jain Source Type: research

Efficacy of mTOR Inhibitors and Intravenous Immunoglobulin for Treatment of Polyoma BK Nephropathy in Kidney Transplant Recipients: A Biopsy-Proven Study
CONCLUSIONS: In patients with polyoma BK virus nephropathy, clearance of viremia and SV40 should not be the sole outcomes to obtain. Aggressive reductions in maintenance immunosuppression and switching to double-drug therapy combined with high-dose intravenous immunoglobulin leads to high rates of graft loss/rejection and sequalae of chronic histological changes.PMID:38385385 | DOI:10.6002/ect.MESOT2023.O29 (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Murat Karatas Erhan Tatar Gokalp Okut Ali Murat Yildirim Emre Kocabas Funda Tasli Alkan Cenk Simsek Sait Murat Dogan Adam Uslu Source Type: research

Efficacy of mTOR Inhibitors and Intravenous Immunoglobulin for Treatment of Polyoma BK Nephropathy in Kidney Transplant Recipients: A Biopsy-Proven Study
CONCLUSIONS: In patients with polyoma BK virus nephropathy, clearance of viremia and SV40 should not be the sole outcomes to obtain. Aggressive reductions in maintenance immunosuppression and switching to double-drug therapy combined with high-dose intravenous immunoglobulin leads to high rates of graft loss/rejection and sequalae of chronic histological changes.PMID:38385385 | DOI:10.6002/ect.MESOT2023.O29 (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Murat Karatas Erhan Tatar Gokalp Okut Ali Murat Yildirim Emre Kocabas Funda Tasli Alkan Cenk Simsek Sait Murat Dogan Adam Uslu Source Type: research

Efficacy of mTOR Inhibitors and Intravenous Immunoglobulin for Treatment of Polyoma BK Nephropathy in Kidney Transplant Recipients: A Biopsy-Proven Study
CONCLUSIONS: In patients with polyoma BK virus nephropathy, clearance of viremia and SV40 should not be the sole outcomes to obtain. Aggressive reductions in maintenance immunosuppression and switching to double-drug therapy combined with high-dose intravenous immunoglobulin leads to high rates of graft loss/rejection and sequalae of chronic histological changes.PMID:38385385 | DOI:10.6002/ect.MESOT2023.O29 (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Murat Karatas Erhan Tatar Gokalp Okut Ali Murat Yildirim Emre Kocabas Funda Tasli Alkan Cenk Simsek Sait Murat Dogan Adam Uslu Source Type: research

Efficacy of mTOR Inhibitors and Intravenous Immunoglobulin for Treatment of Polyoma BK Nephropathy in Kidney Transplant Recipients: A Biopsy-Proven Study
CONCLUSIONS: In patients with polyoma BK virus nephropathy, clearance of viremia and SV40 should not be the sole outcomes to obtain. Aggressive reductions in maintenance immunosuppression and switching to double-drug therapy combined with high-dose intravenous immunoglobulin leads to high rates of graft loss/rejection and sequalae of chronic histological changes.PMID:38385385 | DOI:10.6002/ect.MESOT2023.O29 (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Murat Karatas Erhan Tatar Gokalp Okut Ali Murat Yildirim Emre Kocabas Funda Tasli Alkan Cenk Simsek Sait Murat Dogan Adam Uslu Source Type: research

Efficacy of mTOR Inhibitors and Intravenous Immunoglobulin for Treatment of Polyoma BK Nephropathy in Kidney Transplant Recipients: A Biopsy-Proven Study
CONCLUSIONS: In patients with polyoma BK virus nephropathy, clearance of viremia and SV40 should not be the sole outcomes to obtain. Aggressive reductions in maintenance immunosuppression and switching to double-drug therapy combined with high-dose intravenous immunoglobulin leads to high rates of graft loss/rejection and sequalae of chronic histological changes.PMID:38385385 | DOI:10.6002/ect.MESOT2023.O29 (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Murat Karatas Erhan Tatar Gokalp Okut Ali Murat Yildirim Emre Kocabas Funda Tasli Alkan Cenk Simsek Sait Murat Dogan Adam Uslu Source Type: research