An Unusual Cause of Abdominal Bruit
A 67-year-old male with a history of stage 5 chronic kidney disease and pre-emptive living unrelated kidney transplant eight years prior presented to the clinic with a loud abdominal bruit, 2+ bilateral lower extremity edema, and hypertension. Laboratory evaluation revealed a serum creatinine at baseline levels of 2.5 mg/dL and microscopic hematuria on urinalysis. His post-transplant history was notable for BK virus nephropathy and persistent proteinuria, prompting four transplant biopsies, which ultimately demonstrated recurrent immunotactoid glomerulonephritis. (Source: Urology)
Source: Urology - April 17, 2023 Category: Urology & Nephrology Authors: Ava Mousavi, Justin P. McWilliams, Gabriel M. Danovitch, Nima Nassiri Source Type: research

Current Status, Prevention and Treatment of BK Virus Nephropathy
Acta Medica (Hradec Kralove). 2022;65(4):119-124. doi: 10.14712/18059694.2023.1.ABSTRACTAll renal transplant recipients should undergo a regular screening for BK viral (BKV) viremia. Gradual reduction of immunosuppression is recommended in patients with persistent plasma BKV viremia for 3 weeks after the first detection, reflecting the presence of probable or suspected BKV-associated nephropathy. Reduction of immunosuppression is also a primary intervention in biopsy proven nephropathy associated with BKV (BKVN). Thus, allograft biopsy is not required to treat patients with BKV viremia with stabilized graft function. There...
Source: Acta Medica: Hradec Kralove - March 21, 2023 Category: General Medicine Authors: Ester Kura šová Jakub Štěpán Karel Krej čí Franti šek Mrázek Pavel Sauer Jana Jane čková Tom áš Tichý Source Type: research