BXOS110 Injection in the Treatment of Acute Ischaemic Stroke
Conditions: Acute Ischemic Stroke Interventions: Drug: high-dose BXOS110; Drug: low-dose BXOS110; Drug: Placebo Sponsors: Biocells (Beijing) Biotech Co.,Ltd Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 21, 2024 Category: Research Source Type: clinical trials
Safety and Efficacy Study of CD19-CAR-DNT Cells in Autoimmune Diseases
Conditions: Systemic Lupus Erythematosus; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Idiopathic Inflammatory Myopathies; Systemic Sclerosis Interventions: Biological: CD19-CAR-DNT cells Sponsors: RenJi Hospital; Guangdong Ruishun Biotech Co., Ltd Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 18, 2024 Category: Research Source Type: clinical trials
A Tolerability, Safety and Efficacy Study of RJMty19 in Subjects With Relapsed or Refractory B-NHL
Conditions: B-cell Non-Hodgkin ' s Lymphoma Interventions: Biological: RJMty19 (CD19-CAR-DNT cells) Sponsors: Guangdong Ruishun Biotech Co., Ltd; Ruijin Hospital; Southern Medical University, China; Beijing GoBroad Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 18, 2024 Category: Research Source Type: clinical trials
A Randomized, Double-Blind, Placebo-Controlled, Single-Dose Escalation Phase I Clinical Study to Assess the Safety, Pharmacokinetics, and Immunogenicity of HLX6018 in Healthy Subjects
Conditions: IPF Interventions: Drug: GARP/TGF- β1 monoclonal antibody; Drug: Placebo Sponsors: Shanghai Henlius Biotech Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials
Phase 1 Study to Investigate Safety, Tolerability, PK/PK of J2H-1702 in Healthy Males
Conditions: Non-alcoholic Steatohepatitis Interventions: Drug: Single administration Amg dose Group; Drug: Single administration Bmg dose Group; Drug: Single administration Cmg dose Group; Drug: Single administration Dmg dose Group; Drug: Single administration Emg dose Group; Drug: Single administration Amg dose Group-Placebo; Drug: Single administration Bmg dose Group-Placebo; Drug: Single administration Cmg dose Group-Placebo; Drug: Single administration Dmg dose Group-Placebo; Drug: Single administration Emg dose Group-Placebo; Drug: Multiple administration Amg dose group; Drug: Multiple administration Bmg dose group; D...
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials
Phase 2 Study of WGI-0301 in Combination With Sorafenib for Advanced HCC
Conditions: Advanced Hepatocellular Carcinoma (HCC) Interventions: Drug: WGI-0301 at MTD/RP2D dose IV infusion, QW; Drug: WGI-0301 at MTD/RP2D -1 dose IV infusion, QW; Drug: Sorafenib 400 mg PO, BID continuously; Drug: Sorafenib 400 mg PO, BID Sponsors: Zhejiang Haichang Biotech Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials
A Randomized, Single Intravenous Dose, Parallel Phase I Clinical Study to Compare the Pharmacokinetic Characteristics, Safety, and Immunogenicity of HLX05 Vs. Erbitux ® (Cetuximab) in Healthy Adult Male Chinese Subjects
Conditions: EGFR Overexpression Interventions: Drug: recombinant anti-EGFR human/murine chimeric monoclonal antibody injection Sponsors: Shanghai Henlius Biotech Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials
Phase 1 Study to Investigate Safety, Tolerability, PK/PD of J2H-1702 in Healthy Females
Conditions: Non-alcoholic Steatohepatitis Interventions: Drug: Amg dose administration group; Drug: Amg dose administration group- Placebo; Drug: Bmg dose administration group; Drug: Bmg dose administration group- Placebo Sponsors: J2H Biotech Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials
A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors
Conditions: Locally Advanced or Metastatic Solid Tumors Interventions: Drug: ANS014004 Sponsors: Avistone Biotechnology Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials
Silence Therapeutics Announces Positive Topline 36-Week Data from Ongoing Phase 2 Study of Zerlasiran in Patients with High Lipoprotein(a)
LONDON--(BUSINESS WIRE) March 13, 2024 -- Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the“Company”), an experienced and innovative biotechnology company committed to transforming people’s lives by silencing... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 13, 2024 Category: Pharmaceuticals Source Type: clinical trials
Immunogenicity and Safety of Hecolin ® in HIV Positive/Negative Adults and in Children
Conditions: Hepatitis E Virus Infection Interventions: Biological: Hecolin ® Recombinant Hepatitis E Vaccine; Biological: Isotonic Sodium Chloride injection Sponsors: International Vaccine Institute; Xiamen Innovax Biotech Co., Ltd; Bill and Melinda Gates Foundation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 12, 2024 Category: Research Source Type: clinical trials
Study to evaluate the willingness of healthy volunteers, patients, doctors and pharmaceutical/biotechnology industry to use a platform (web or app) to facilitate recruitment and engagement in early phase clinical trials . a survey study.
Conditions: Willingness of Healthy Volunteers, Patients, Doctors and Pharm/Biotech Industry to Use a Platform to Facilitate Recruitment in Early Phase Clinical Trials Interventions: Other: Questionnaires Sponsors: Instituto de Investigaci ón Hospital Universitario La Paz Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials
Study of ATX-01 in Participants With DM1
Conditions: Myotonic Dystrophy 1 Interventions: Drug: ATX-01; Drug: Placebo Sponsors: ARTHEx Biotech S.L. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials
Phase I Clinical Study of Tumor-associated Lymph Node T Cell Therapy for Advanced Solid Tumors
Conditions: Advanced Solid Tumor; Tumor Associated Lymph Node T Cell; Immunotherapy Interventions: Drug: Tumor Associated Lymph node T cell; Drug: cyclophosphamide; Drug: IL-2; Drug: Serplulimab Injection Sponsors: Guangzhou FineImmune Biotechnology Co., LTD. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials
Phase 2a Study to Evaluate Safety and Explore Efficacy of J2H-1702 for NASH
Conditions: Non-alcoholic Steatohepatitis Interventions: Drug: J2H-1702; Drug: J2H-1702; Drug: J2H-1702; Drug: Placebo Sponsors: J2H Biotech Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
