An anti-CRISPR system that helps save viruses from destruction
In this episode:00:47 An RNA-based viral system that mimics bacterial immune defencesTo protect themselves against viral infection, bacteria often use CRISPR-Cas systems to identify and destroy an invading virus’s genetic material. But viruses aren’t helpless and can deploy countermeasures, known as anti-CRISPRs, to neutralise host defences. This week, a team describe a new kind of anti-CRISPR system, based on RNA, which protects viruses by mimicking part of the CRISPR-Cas system. The researchers hope that this discovery could have future biotechnology applications, including making CRISPR-Cas genome editing more preci...
Source: Nature Podcast - October 18, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Legal Risks of Abortion Miscoding
Intentional miscoding of abortion services may put clinicians and hospital systems at legal risk. JAMA Senior Editor Linda Brubaker, MD, MS, and Carmel Shachar, JD, MPH, from the Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics, Harvard Law School, discuss the risks of intentional miscoding practices and possible penalties. Related Content: Abortion Miscoding—Legal Risks for Clinicians and Hospital Systems (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - June 13, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 939: From lizards to Lassa with Tom Monath
Tom Monath joins TWiV to discuss his wide-ranging career that includes medicine, field work and vaccine development while working for the US government, the US military, and multiple biotechnology companies. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit Guest: Tom Monath Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t-shirt (Vaccinated.us) Fever by John Fuller (Amazon) Crozet BioPharma Timestamps by Jolene. Thanks! Weekly Picks Dickson – Jazz – Small...
Source: This Week in Virology - MP3 Edition - September 25, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

How humans adapted to digest lactose — after thousands of years of milk drinking
We present its grim findingsNature News: Supercharged biotech rice yields 40% more grainSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. See acast.com/privacy for privacy and opt-out information. (Source: Nature Podcast)
Source: Nature Podcast - July 27, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronapod: How African scientists are copying Moderna's COVID vaccine
Vaccine inequity continues to be one of the greatest challenges in the pandemic - with only 10% of those in low- and middle-income countries fully vaccinated. One of the biggest hold-ups is a lack of vaccine manufacturing capacity in poorer nations. But now, researchers at the WHO technology-transfer hub have completed the first step in a project aimed at building vaccine manufacturing capacity in the Global South, by successfully replicating Moderna's COVID vaccine without assistance from the US-based biotech company. In this episode of Coronapod, we ask how they did it? What happens next? What the legal ramification...
Source: Nature Podcast - February 11, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronapod: How African scientists are copying Moderna's COVID vaccine
Vaccine inequity continues to be one of the greatest challenges in the pandemic - with only 10% of those in low- and middle-income countries fully vaccinated. One of the biggest hold-ups is a lack of vaccine manufacturing capacity in poorer nations. But now, researchers at the WHO technology-transfer hub have completed the first step in a project aimed at building vaccine manufacturing capacity in the Global South, by successfully replicating Moderna's COVID vaccine without assistance from the US-based biotech company. In this episode of Coronapod, we ask how they did it? What happens next? What the legal ramification...
Source: Nature Podcast - February 11, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

What ’s the best diet for people and the planet?
Designing a nutritious and planet-friendly diet, and an AI that guides mathematicians.In this episode:00:46 Designing a healthy diet for the planetResearchers are trying to develop diets that help to reduce greenhouse gas emissions while at the same time providing nutrition. Some of these sustainable diets are now being tested to see if they work in local contexts without damaging livelihoods.Feature: What humanity should eat to stay healthy and save the planet08:24 Research HighlightsHow jellyfish get by without a centralised brain, and reading the runes within a medieval lead amulet.Research Highlight: How jellyfish cont...
Source: Nature Podcast - December 1, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts

What ’s the best diet for people and the planet?
Designing a nutritious and planet-friendly diet, and an AI that guides mathematicians.In this episode:00:46 Designing a healthy diet for the planetResearchers are trying to develop diets that help to reduce greenhouse gas emissions while at the same time providing nutrition. Some of these sustainable diets are now being tested to see if they work in local contexts without damaging livelihoods.Feature: What humanity should eat to stay healthy and save the planet08:24 Research HighlightsHow jellyfish get by without a centralised brain, and reading the runes within a medieval lead amulet.Research Highlight: How jellyfish cont...
Source: Nature Podcast - December 1, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 813: COVID-19 at the European Society for Clinical Virology
From the 2021 online meeting of the European Society for Clinical Virology, Vincent speaks with meeting speakers on COVID-19 vaccines, immunity, how countries responded to the pandemic, and how to prepare for the next one. Host: Vincent Racaniello Guests: Sarah Gilbert, Florian Krammer, Fausto Baldanti, Thea Fischer, Ron Fouchier, and Catherine Moore Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Correlate of protection needed for COVID-19 vaccines (Nat Med) Simian adenoviruses as vaccine vectors (Future Viral) Early SARS-CoV-2 spread in Lombardy (Nat Comm) SA...
Source: This Week in Virology - MP3 Edition - October 7, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 732: Citizen science with Forest Rohwer and Maria-Isabel Rojas
Forest and Maria-Isabel join TWiV to discuss their their project to engage thousands of citizens to swab inanimate surfaces in the San Diego area, then send the samples to the Rohwer Lab for nucleic acid analysis. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Forest on TWiV 391 Swabbing surfaces in San Diego (10News) Nido21 meeting Molnupiravir in phase 2a (Fierce Biotech) Letters read on TWiV 732 Timestamps by Jolene. Thanks! Weekly Picks Dickson – 10 amazing scie...
Source: This Week in Virology - MP3 Edition - March 18, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 708: Alpaca llama full of nanobodies
The TWiVy team deconstructs CoronaVac, the inactivated SARS-CoV-2 vaccine produced by Sinovac Biotech, and production of multivalent camelid nanobodies that block infection with the virus and suppress selection of neturalization-resistant variants. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode David Kessler to head Operation Warp Speed (NY Times) Phase 1/2 results of Sinovac inactivated vaccine (Lancet) beta-propiolactone (Wikipedia) Multivalent anti-SARS-CoV-2 nanobodie...
Source: This Week in Virology - MP3 Edition - January 17, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Fish farming ’s future, and how microbes compete for space on our face
These days about half of the protein the world’s population eats is from seafood. Staff Writer Erik Stokstad joins host Sarah Crespi to talk about how brand-new biotech and old-fashion breeding programs are helping keep up with demand, by expanding where we can farm fish and how fast we can grow them. Sarah also spoke with Jan Claesen, an assistant professor at the Cleveland Clinic’s Lerner Research Institute, about skin microbes that use their own antibiotic to fight off harmful bacteria. Understanding the microbes native to our skin and the molecules they produce could lead to treatments for skin disorders such as a...
Source: Science Magazine Podcast - November 19, 2020 Category: Science Authors: Science Magazine Source Type: podcasts

Fish farming ’s future, and how microbes compete for space on our face
These days about half of the protein the world’s population eats is from seafood. Staff Writer Erik Stokstad joins host Sarah Crespi to talk about how brand-new biotech and old-fashion breeding programs are helping keep up with demand, by expanding where we can farm fish and how fast we can grow them. Sarah also spoke with Jan Claesen, an assistant professor at the Cleveland Clinic’s Lerner Research Institute, about skin microbes that use their own antibiotic to fight off harmful bacteria. Understanding the microbes native to our skin and the molecules they produce could lead to treatments for skin disorders s...
Source: Science Magazine Podcast - November 19, 2020 Category: Science Authors: Science Magazine Source Type: podcasts