Molecular Origami: The Delicate Art of Protein Folding and Misfolding and Its Relevance to Health and Disease
NIH Director ’ s Wednesday Afternoon Lecture Series
Judith Frydman is a biochemist and the Donald Kennedy Chair in the School of Humanities& Sciences and Professor of Genetics at Stanford University. Her research focuses on protein folding. Her laboratory discovered the molecular chaperone TRiC/CCT and determined its mechanism and function for protein folding. She was elected as a Fellow of the American Academy of Arts& Sciences in 2018 and as a Fellow of the Biophysical Society in 2019. In 2017, she was given the American Society for Biochemistry and Molecular Biology – Merck Award. She is an editor of the Journal of ...
Source: Videocast - All Events - August 29, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
Protein Design Using Deep Learning
David Baker is head of the Institute for Protein Design and the Henrietta and Aubrey Davis Endowed Professor in Biochemistry at University of Washington, Seattle.For more information go tohttps://oir.nih.gov/walsAir date: 12/14/2022 2:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - August 16, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
Single-Molecule Studies of Homologous Recombination
Speaker Eric Greene uses single-molecule optical microscopy to study fundamental interactions between proteins and nucleic acids. " Our overall goal is to reveal the molecular mechanisms that cells use to repair, maintain, and decode their genetic information. This research combines aspects of biochemistry, physics, and nanoscale technology to answer questions about complex biological problems that cannot be easily addressed through traditional biochemical approaches. As part of our work, we have established robust experimental platforms that enable single molecule imaging of biochemical reaction mechanisms in a “ high t...
Source: Videocast - All Events - November 22, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
COVID-19 Scientific Interest Group: Human Antibody Response to SARS-CoV-2 Infection and Vaccination
COVID-19 Scientific Interest Group
Michel C. Nussenzweig is the Zanvil A. Cohn and Ralph M. Steinman Professor and Investigator, Howard Hughes Medical Institute. The Nussenzweig ’ s laboratory studies the molecular aspects of the immune system ’ s innate and adaptive responses using a combination of biochemistry, molecular biology, and genetics. For work on adaptive immunity, he focuses on B lymphocytes and antibodies to HIV-1, while his studies of innate immunity focus on dendritic cells. His work is leading to new antibody-based therapies for infections by HIV and the novel SARS-CoV-2 coronavirus, among other viruses...
Source: Videocast - All Events - September 23, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
The Neurosciences: Degenerative Disorders, Neuroplasticity, & Intersection with Glycoscience Symposium [Day 1]
The NIH Common Fund Glycoscience Program (CF-GSP) in conjunction with NIA and NIDA have organized this " Neurosciences: Degenerative Disorders, Neuroplasticity,& Intersection with Glycoscience " symposium, which will be held virtually on September 8& 9, 2021 from 10:00 a.m. to 4:30 p.m. EDT daily. This symposium is being Co-chaired by Dr. Catherine Leimkuhler Grimes, Chair, CF-GSP Tools Group& Professor, Department of Chemistry& Biochemistry, University of Delaware; Dr. Ronald Schnaar, John Jacob Abel Professor of Pharmacology, Department of Pharmacology and Molecular Sciences& Department of Neuroscience, Johns Hopkins Sch...
Source: Videocast - All Events - August 5, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Researchers have taken a key step toward developing new drugs and vaccines to combat COVID-19.
Researchers at the Oregon State University Biochemistry Department have taken a key step toward developing new drugs and vaccines to combat COVID-19.This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - May 12, 2021 Category: Science Source Type: video
Demystifying Medicine: Reporting Science to Public/How “ Science ” Adapts to the Pandemic
Demystifying Medicine Lecture Series
Washington Post Health and Science editor Stephen Smith will describe the newspaper's decisions in reporting science to the general public; and Science editor Valda Vinson, Ph.D., will discuss how science … and Science … adapted to the pandemic.
Smith became the Post's Health and Science editor during an emerging pandemic, in July 2020. Pressed into service, he and his colleagues needed to present a mix of breaking news, accurate health information, and fair criticism of the often-confused U.S. response to the pandemic. One challenge that Smith faced was to not politicize pandemic r...
Source: Videocast - All Events - April 30, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Quasi-species Suppression of Viral Drug Resistance
NIH Director ’ s Wednesday Afternoon Lecture Series
This is the annual George Khoury Lecture, which honors the memory of Dr. George Khoury (1943 – 1987), a highly regarded NIH virologist and caring mentor of the postdoctoral fellows in his laboratory.
Dr. Karla Kirkegaard, Ph.D., is the Violetta L. Horton Research Professor of Genetics at the Stanford University School of Medicine. Her laboratory focuses on identification of dominant drug targets for antiviral design, such as small molecules that stabilize oligomeric assemblages. A past recipient of the NIH Director's Pioneer Award, Dr. Kirkegaard combines her interest...
Source: Videocast - All Events - March 1, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
David Derse Memorial Lecture: Silencing of Retroviral DNA's
HIV DRP Presents the 9th Annual David Derse Memorial Lecture " Silencing of Retroviral DNA's "
This annual event honors the outstanding research accomplishments of David Derse, Ph.D., a Principal Investigator in the Center for Cancer Research's HIV Dynamics and Replication Program (HIV DRP).
Dr. Derse was Head of the Retrovirus Gene Expression Section in the HIV DRP. During his 25 years at the National Cancer Institute, he investigated the molecular mechanisms of retrovirus infection and replication, concentrating most recently on the human viruses HIV-1 and HTLV-1. In 2007, Dr. Derse and his research team discovered how H...
Source: Videocast - All Events - November 5, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
NLM Ada Lovelace Computational Health Lecture Series Dynamic Genome Rearrangements in the Ciliate Oxytricha presented by Laura Landweber, Ph.D. Professor of Biochemistry & Molecular Biophysics and of Biological Sciences, Columbia University
The ciliate Oxytricha trifallax possesses a complex pair of genomes, and massive DNA rearrangements produce a highly fragmented but functional somatic macronucleus from a complex germline micronucleus. This process eliminates nearly all noncoding DNA, including transposons, and rearranges over 225,000 short DNA segments to produce a second genome containing thousands of gene-sized " nanochromosomes ” . The mature, somatic genome contains over 17,000 nanochromosomes. Noncoding RNAs regulate the entire process of genome rearrangement. Millions of parental 27nt small RNAs provide the critical information to mark and protect...
Source: Videocast - All Events - October 13, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Human antibody responses to SARS-CoViD-2
NIH Director's Wednesday Afternoon Lecture Series
Annual William E. Paul Lecture – – Dr. Nussenzweig ’ s laboratory studies the molecular aspects of the immune system ’ s innate and adaptive responses using a combination of biochemistry, molecular biology, and genetics. For work on adaptive immunity, he focuses on B lymphocytes and antibodies to HIV-1, while his studies of innate immunity focus on dendritic cells. His work is leading to new antibody-based therapies for infections by HIV and the novel SARS-CoV-2 coronavirus, among other viruses.For more information go tohttps://oir.nih.gov/wals/about-walsAir date: 1...
Source: Videocast - All Events - September 14, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
New Tools to Explore the Biology of Bacterial Polysaccharides
NIH Common Fund Glycoscience Program (CF-GSP) workshop " New Tools to Explore the Biology of Bacterial Polysaccharides "
This workshop is being Co-chaired by Dr. Catherine Leimkuhler Grimes, Chair, CF-GSP Tools Group& Professor, Department of Chemistry& Biochemistry, University of Delaware& Dr. Danielle Dube, ACS CARB Division Secretary& Professor of Chemistry& Biochemistry, Bowdoin College. Presentations will highlight the latest findings of NIH supported researchers who are developing new methods and tools for the study of microbes and applying these tools to understand bacterial metabolism, interaction(s) with the immun...
Source: Videocast - All Events - July 30, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
DNA's helix may have arisen with startling ease (Image 4)
A model of an RNA helix. A new study led by Nicholas Hud, a Regents Professor in Georgia TechÂs School of Chemistry and Biochemistry, suggests the rotation in DNA and RNA may have occurred with ease billions of years ago when RNAÂs chemical ancestors casually spun into spiraled strands. [Image 4 ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - August 19, 2019 Category: Science Source Type: video
DNA's helix may have arisen with startling ease (Image 3)
A new study led by Nicholas Hud, a Regents Professor in Georgia TechÂs School of Chemistry and Biochemistry, suggests the rotation in DNA and RNA may have occurred with ease billions of years ago when RNAÂs chemical ancestors casually spun into spiraled strands. This artwork, produced for the ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - August 19, 2019 Category: Science Source Type: video
Brilliant glow of paint-on semiconductors (Image 1)
Carlos Silva (left), a professor at Georgia TechÂs School of Chemistry and Biochemistry, and graduate research assistant Félix Thouin examine a setup to process laser light in the visible range for the testing of quantum properties in a halide organic-inorganic perovskite. Silva was co-lead ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - June 20, 2019 Category: Science Source Type: video
