Integrated analyses delineate distinctive immunological pathways and diagnostic signatures for Behcet ’s disease by leveraging gene microarray data
AbstractBehcet ’s disease (BD) is a chronic inflammatory vasculitis and clinically heterogeneous disorder caused by immunocyte aberrations. Comprehensive research on gene expression patterns in BD illuminating its aetiology is lacking. E-MTAB-2713 downloaded from ArrayExpress was analysed to screen differentiall y expressed genes (DEGs) using limma. Random forest (RF) and neural network (NN) classification models composed of gene signatures were established using the E-MTAB-2713 training set and subsequently verified using GSE17114. Single sample gene set enrichment analysis was used to assess immunocyte in filtration. A...
Source: Immunologic Research - June 21, 2023 Category: Allergy & Immunology Source Type: research

Hiding in plain sight: how the COVID-19 pandemic unmasked the autoinflammatory PFAPA syndrome lurking in our midst
Periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome is the most common autoinflammatory syndrome of childhood, particularly among non-Mediterranean populations.1 The condition is characterised by recurrent and periodic episodes of unprovoked systemic inflammation (fevers and raised acute phase reactants) lasting 3–7 days that are often accompanied by localised inflammation (stomatitis, pharyngitis and adenitis). The underlying aetiopathogenesis of PFAPA syndrome remains a mystery, but various patterns of dysregulated innate and T-cell immune responses have been described.1 Approximately one...
Source: Archives of Disease in Childhood - June 19, 2023 Category: Pediatrics Authors: Sinnappurajar, P., Ramanan, A. V., Goenka, A. Tags: COVID-19 Viewpoint Source Type: research

Management of Central Diabetes Insipidus in Disabled Children with Diluted Oral Desmopressin Lyophilisate Formulation Administered Through Nasogastric Tube: A Retrospective Case Series
CONCLUSIONS: Nasogastric administration of oral DDAVP lyophilised formulation was safe and effective in the treatment of CDI in disabled children in this small retrospective series.PMID:37326929 | DOI:10.1007/s40272-023-00578-7 (Source: Paediatric Drugs)
Source: Paediatric Drugs - June 16, 2023 Category: Pediatrics Authors: H üseyin Anıl Korkmaz Ved Bhushan Arya Ahmet G önüllü Fulya Co şkunol Behzat Ozkan Source Type: research

Management of Central Diabetes Insipidus in Disabled Children with Diluted Oral Desmopressin Lyophilisate Formulation Administered Through Nasogastric Tube: A Retrospective Case Series
CONCLUSIONS: Nasogastric administration of oral DDAVP lyophilised formulation was safe and effective in the treatment of CDI in disabled children in this small retrospective series.PMID:37326929 | DOI:10.1007/s40272-023-00578-7 (Source: Paediatric Drugs)
Source: Paediatric Drugs - June 16, 2023 Category: Pediatrics Authors: H üseyin Anıl Korkmaz Ved Bhushan Arya Ahmet G önüllü Fulya Co şkunol Behzat Ozkan Source Type: research

Management of Central Diabetes Insipidus in Disabled Children with Diluted Oral Desmopressin Lyophilisate Formulation Administered Through Nasogastric Tube: A Retrospective Case Series
CONCLUSIONS: Nasogastric administration of oral DDAVP lyophilised formulation was safe and effective in the treatment of CDI in disabled children in this small retrospective series.PMID:37326929 | DOI:10.1007/s40272-023-00578-7 (Source: Paediatric Drugs)
Source: Paediatric Drugs - June 16, 2023 Category: Pediatrics Authors: H üseyin Anıl Korkmaz Ved Bhushan Arya Ahmet G önüllü Fulya Co şkunol Behzat Ozkan Source Type: research

Management of Central Diabetes Insipidus in Disabled Children with Diluted Oral Desmopressin Lyophilisate Formulation Administered Through Nasogastric Tube: A Retrospective Case Series
CONCLUSIONS: Nasogastric administration of oral DDAVP lyophilised formulation was safe and effective in the treatment of CDI in disabled children in this small retrospective series.PMID:37326929 | DOI:10.1007/s40272-023-00578-7 (Source: Paediatric Drugs)
Source: Paediatric Drugs - June 16, 2023 Category: Pediatrics Authors: H üseyin Anıl Korkmaz Ved Bhushan Arya Ahmet G önüllü Fulya Co şkunol Behzat Ozkan Source Type: research

Management of Central Diabetes Insipidus in Disabled Children with Diluted Oral Desmopressin Lyophilisate Formulation Administered Through Nasogastric Tube: A Retrospective Case Series
CONCLUSIONS: Nasogastric administration of oral DDAVP lyophilised formulation was safe and effective in the treatment of CDI in disabled children in this small retrospective series.PMID:37326929 | DOI:10.1007/s40272-023-00578-7 (Source: Paediatric Drugs)
Source: Paediatric Drugs - June 16, 2023 Category: Pediatrics Authors: H üseyin Anıl Korkmaz Ved Bhushan Arya Ahmet G önüllü Fulya Co şkunol Behzat Ozkan Source Type: research

Management of Central Diabetes Insipidus in Disabled Children with Diluted Oral Desmopressin Lyophilisate Formulation Administered Through Nasogastric Tube: A Retrospective Case Series
CONCLUSIONS: Nasogastric administration of oral DDAVP lyophilised formulation was safe and effective in the treatment of CDI in disabled children in this small retrospective series.PMID:37326929 | DOI:10.1007/s40272-023-00578-7 (Source: Paediatric Drugs)
Source: Paediatric Drugs - June 16, 2023 Category: Pediatrics Authors: H üseyin Anıl Korkmaz Ved Bhushan Arya Ahmet G önüllü Fulya Co şkunol Behzat Ozkan Source Type: research

Management of Central Diabetes Insipidus in Disabled Children with Diluted Oral Desmopressin Lyophilisate Formulation Administered Through Nasogastric Tube: A Retrospective Case Series
CONCLUSIONS: Nasogastric administration of oral DDAVP lyophilised formulation was safe and effective in the treatment of CDI in disabled children in this small retrospective series.PMID:37326929 | DOI:10.1007/s40272-023-00578-7 (Source: Paediatric Drugs)
Source: Paediatric Drugs - June 16, 2023 Category: Pediatrics Authors: H üseyin Anıl Korkmaz Ved Bhushan Arya Ahmet G önüllü Fulya Co şkunol Behzat Ozkan Source Type: research

Management of Central Diabetes Insipidus in Disabled Children with Diluted Oral Desmopressin Lyophilisate Formulation Administered Through Nasogastric Tube: A Retrospective Case Series
CONCLUSIONS: Nasogastric administration of oral DDAVP lyophilised formulation was safe and effective in the treatment of CDI in disabled children in this small retrospective series.PMID:37326929 | DOI:10.1007/s40272-023-00578-7 (Source: Paediatric Drugs)
Source: Paediatric Drugs - June 16, 2023 Category: Pediatrics Authors: H üseyin Anıl Korkmaz Ved Bhushan Arya Ahmet G önüllü Fulya Co şkunol Behzat Ozkan Source Type: research

Management of Central Diabetes Insipidus in Disabled Children with Diluted Oral Desmopressin Lyophilisate Formulation Administered Through Nasogastric Tube: A Retrospective Case Series
CONCLUSIONS: Nasogastric administration of oral DDAVP lyophilised formulation was safe and effective in the treatment of CDI in disabled children in this small retrospective series.PMID:37326929 | DOI:10.1007/s40272-023-00578-7 (Source: Paediatric Drugs)
Source: Paediatric Drugs - June 16, 2023 Category: Pediatrics Authors: H üseyin Anıl Korkmaz Ved Bhushan Arya Ahmet G önüllü Fulya Co şkunol Behzat Ozkan Source Type: research

Management of Central Diabetes Insipidus in Disabled Children with Diluted Oral Desmopressin Lyophilisate Formulation Administered Through Nasogastric Tube: A Retrospective Case Series
CONCLUSIONS: Nasogastric administration of oral DDAVP lyophilised formulation was safe and effective in the treatment of CDI in disabled children in this small retrospective series.PMID:37326929 | DOI:10.1007/s40272-023-00578-7 (Source: Paediatric Drugs)
Source: Paediatric Drugs - June 16, 2023 Category: Pediatrics Authors: H üseyin Anıl Korkmaz Ved Bhushan Arya Ahmet G önüllü Fulya Co şkunol Behzat Ozkan Source Type: research