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Maternal Viral Infection in Early Pregnancy and Risk of Congenital Heart Disease in Offspring: A Prospective Cohort Study in Central China
CONCLUSION: Our study proposed evidence that maternal virus infection in early pregnancy, including HBV, coxsackievirus-B, HCMV, and rubella virus, was implicated in CHD, although more studies remain needed to verify the results, especially associations in specific CHD phenotypes.PMID:35082532 | PMC:PMC8784951 | DOI:10.2147/CLEP.S338870 (Source: Herpes)
Source: Herpes - January 27, 2022 Category: Infectious Diseases Authors: Tingting Wang Qiongxuan Li Lizhang Chen Bin Ni Xiaoqi Sheng Peng Huang Senmao Zhang Jiabi Qin Source Type: research

Heart Rate Recovery Following Exercise Testing in Pediatric Patients with Acyanotic Repaired Congenital Heart Disease
AbstractAttenuated heart rate recovery (HRR) following peak exercise has been shown to be a predictor of mortality in populations of adults with Fontan palliation, coronary artery disease, heart failure, and heart transplantation. However, few have studied HRR in children and adolescents with congenital heart disease (CHD). This case-control  study compared HRR patterns from exercise stress testing in children and adolescents with and without repaired acyanotic CHD (raCHD). Retrospective analysis included patients aged 10–18 years who had exercise testing between 2007 and 2017. The raCHD cohort included patients with ...
Source: Pediatric Cardiology - January 4, 2022 Category: Cardiology Source Type: research

Maternal use of cough medications during early pregnancy and selected birth defects: a US multisite, case-control study
Conclusions Maternal use of medications containing DM alone, GG alone or DM +GG showed positive associations with a small number of birth defects. These observations, which should be interpreted with caution due to small proportions of exposed mothers, may represent true signals or chance findings and warrant evaluation in future studies. (Source: BMJ Open)
Source: BMJ Open - December 30, 2021 Category: General Medicine Authors: Cao, Y., Rhoads, A., Burns, T., Carnahan, R. M., Conway, K. M., Werler, M. M., Mitchell, A., Romitti, P. Tags: Open access, Epidemiology, COVID-19 Source Type: research

Long-Term Outcome Up To 40 Years after Single Patch Repair of Complete Atrioventricular Septal Defect in Infancy or Childhood
CONCLUSION: Up to 40 years after single-patch repair of CAVSD, clinical status and functional results are promising, particularly, in terms of atrioventricular valve function. Permanent pacemaker therapy results in a life-long need for surgical reinterventions.PMID:34953470 | DOI:10.1055/s-0041-1740070 (Source: The Thoracic and Cardiovascular Surgeon)
Source: The Thoracic and Cardiovascular Surgeon - December 25, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Stefanie Reynen Hedwig H H övels-Gürich Jaime F Vazquez-Jimenez Bruno J Messmer Joerg S Sachweh Source Type: research

Long-Term Outcome Up To 40 Years after Single Patch Repair of Complete Atrioventricular Septal Defect in Infancy or Childhood
CONCLUSION: Up to 40 years after single-patch repair of CAVSD, clinical status and functional results are promising, particularly, in terms of atrioventricular valve function. Permanent pacemaker therapy results in a life-long need for surgical reinterventions.PMID:34953470 | DOI:10.1055/s-0041-1740070 (Source: The Thoracic and Cardiovascular Surgeon)
Source: The Thoracic and Cardiovascular Surgeon - December 25, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Stefanie Reynen Hedwig H H övels-Gürich Jaime F Vazquez-Jimenez Bruno J Messmer Joerg S Sachweh Source Type: research

Long-Term Outcome Up To 40 Years after Single Patch Repair of Complete Atrioventricular Septal Defect in Infancy or Childhood
CONCLUSION: Up to 40 years after single-patch repair of CAVSD, clinical status and functional results are promising, particularly, in terms of atrioventricular valve function. Permanent pacemaker therapy results in a life-long need for surgical reinterventions.PMID:34953470 | DOI:10.1055/s-0041-1740070 (Source: The Thoracic and Cardiovascular Surgeon)
Source: The Thoracic and Cardiovascular Surgeon - December 25, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Stefanie Reynen Hedwig H H övels-Gürich Jaime F Vazquez-Jimenez Bruno J Messmer Joerg S Sachweh Source Type: research

Incidentally detected atrioventricular septal defect in an adult
We should know that adult congenital heart diseases with no symptoms are incidentally detected. AbstractA 34-year-old woman, a liver transplantation donor for her son, was referred to our hospital for preoperative evaluation. She was diagnosed with an incomplete atrioventricular septal defect (AVSD). She underwent double valve repair and patch closure of the defect. Incidental discovery of an asymptomatic AVSD in an adult is rare. (Source: Clinical Case Reports)
Source: Clinical Case Reports - December 22, 2021 Category: General Medicine Authors: Risa Shimbori, Jun Takaki, Yasuhito Hosoda, Ken Okamoto, Koji Fukae, Toshihiro Fukui Tags: CASE REPORT Source Type: research

Prevalence of congenital heart disease among patients with down syndrome in Southwestern Saudi Arabia
Conclusion: The prevalence of CHD in the study group was consistent with reports from other regions of Saudi Arabia and globally. Participants' sex was not associated with the occurrence of CHD in DS patients in this study. (Source: Annals of African Medicine)
Source: Annals of African Medicine - December 3, 2021 Category: African Health Authors: Magaji Garba Taura Abdullah Mohammed Alshahrani Dhafer Obeid Alqahtani Source Type: research