Hydrogels Loaded with Atorvastatin-Metal Organic Framework Have a Preventive Effect on Coronary Heart Disease
Chem Biodivers. 2023 Dec 8:e202301511. doi: 10.1002/cbdv.202301511. Online ahead of print.ABSTRACTIn the research, a new three-dimensional coordination polymer was synthesized by solvothermal method based on the metal ligand LCu =[Cu(2,4-pydca)2 ]2- (2,4-pydca=pyridine-2,4-dicarboxylate) and alkaline-earth ion CaII with chemical composition {[Ca(H2 O)2 ][LCu ]⋅DMSO ⋅ 2H2 O}n (1) (DMSO=dimethyl sulfoxide). The complex 1 was characterized soundly by Fourier transform infrared (FT-IR) spectroscopy, elemental analysis (EA), single-crystal X-ray diffraction (SCXRD) and thermogravimetric analysis (TGA). Using atorvastatin as...
Source: Chemistry and Biodiversity - December 8, 2023 Category: Biochemistry Authors: Xinghua Bai Jun Jiang Sijia Tu Weizong Zhang Source Type: research

Hydrogels Loaded with Atorvastatin-Metal Organic Framework Have a Preventive Effect on Coronary Heart Disease
Chem Biodivers. 2023 Dec 8:e202301511. doi: 10.1002/cbdv.202301511. Online ahead of print.ABSTRACTIn the research, a new three-dimensional coordination polymer was synthesized by solvothermal method based on the metal ligand LCu =[Cu(2,4-pydca)2 ]2- (2,4-pydca=pyridine-2,4-dicarboxylate) and alkaline-earth ion CaII with chemical composition {[Ca(H2 O)2 ][LCu ]⋅DMSO ⋅ 2H2 O}n (1) (DMSO=dimethyl sulfoxide). The complex 1 was characterized soundly by Fourier transform infrared (FT-IR) spectroscopy, elemental analysis (EA), single-crystal X-ray diffraction (SCXRD) and thermogravimetric analysis (TGA). Using atorvastatin as...
Source: Chemistry and Biodiversity - December 8, 2023 Category: Biochemistry Authors: Xinghua Bai Jun Jiang Sijia Tu Weizong Zhang Source Type: research

An update on combination therapies for multiple sclerosis: where are we now?
Expert Rev Neurother. 2023 Dec 6:1-15. doi: 10.1080/14737175.2023.2289572. Online ahead of print.ABSTRACTINTRODUCTION: In theory, combination of two agents, which are suboptimal when given individually, may result in a significant increase in therapeutic effect. Combination therapies have proven particularly effective against infections such as HIV, cancer, and also chronic autoimmune diseases such as rheumatoid arthritis.AREAS COVERED: The authors review the literature, searching for randomized placebo-controlled or comparative, double-blind or investigator-blinded clinical trials, not including open label clinical trials...
Source: Expert Review of Neurotherapeutics - December 7, 2023 Category: Neurology Authors: Per Soelberg Sorensen Melinda Magyari Finn Sellebjerg Source Type: research