Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins
Chem Phys Lipids. 2024 Feb 5;260:105377. doi: 10.1016/j.chemphyslip.2024.105377. Online ahead of print.ABSTRACTAtorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited drug solubility while the PAC drug is unstable upon exposure to the atmospheric oxygen. Herein, the lyotropic liquid crystalline nanoparticles (LLCNPs) constructed by a binary mixture of soy phosphatidylcholine (SPC) and citric acid ester of monoglyceride (citrem) at different wei...
Source: Chemistry and Physics of Lipids - February 7, 2024 Category: Lipidology Authors: Mardhiah Maslizan Muhammad Salahuddin Haris Mokrish Ajat Siti Nurul Ain Md Jamil Shah Christirani Azhar N Idayu Zahid Intan Diana Mat Azmi Source Type: research
