High-Sensitivity Troponin is not a Myth, and “Myth-busting” is often another Myth to be Busted
Conclusion: Early rule out protocol is effective and safe.We refer interested readers to the following excellent reviews of high-sensitivity troponin implementation:Twerenbold, R. et al.JACC70 (8): 996 –1012.https://doi.org/10.1016/j.jacc.2017.07.718.Yader S. et al. 2016. Am J Med 129 (4): 354 –65.https://doi.org/10.1016/j.amjmed.2015.12.005.Response to the 2nd “Myth-busting” articleInterestingly, on Nov 5, Dr. Spiegel publishedanother “Myths in EM” piece in EM News: “Is hs-cTnT Worth the Downstream Testing?. The piece assesses a new randomized trial of the Roche hs -cTnT (not the Abbott Troponin I,...
Source: Dr. Smith's ECG Blog - November 9, 2019 Category: Cardiology Authors: Steve Smith Source Type: blogs

Health Insurer Plans To Optimize Drug Treatment Using Data Analytics
New Jersey’s largest health insurer has partnered with a biopharma vendor to optimize drug treatment using medical and pharmacy claims data.  Horizon Healthcare Services will work with vendor Aetion to support case management strategies and develop value-based agreements with pharmas targeting specific patient populations. Aetion is in the business of providing payers and biopharma companies […] (Source: EMR and HIPAA)
Source: EMR and HIPAA - June 17, 2019 Category: Information Technology Authors: Anne Zieger Tags: Ambulatory Analytics/Big Data Clinical Healthcare IT Hospital - Health System Aetion AstraZeneca Boehringer Ingelheim Eli Lilly and Company Geisinger Horizon Healthcare Services Type 2 Diabetes UPMC Health Plan Value-Based Contra Source Type: blogs

You Can ’ t Suppress the Data
As we are all learning, if you try and suppress research data, you’re ultimately going to fail. Especially if you’ve previously made such data available to the U.S. Food and Drug Administration, or even discuss the data in an email. Companies need to be ready to come clean with even negative data about their products, because only the complete picture will be considered by the people prescribed your product. A company has to make a decision — forfeit some profit in the short-term and acknowledge their drug isn’t the best thing since sliced bread, or forfeit lots of reputation, trust and brand value ...
Source: World of Psychology - May 24, 2019 Category: Psychiatry & Psychology Authors: John M. Grohol, Psy.D. Tags: General 1980s 1990s 31 Million Antipsychotic Drug Astrazeneca Atypical Antipsychotic Best Thing Since Sliced Bread Brand Strategy Food And Drug Food And Drug Administration Johnson Johnson Mcneil Mental Health Trust Parent Comp Source Type: blogs

The Transparency International 2018 Corporate Political Engagement Index- Pharma Appears All Too Comfortable with the Revolving Door and Making Opaque Political Contributions
(Source: Health Care Renewal)
Source: Health Care Renewal - March 21, 2019 Category: Health Management Tags: AstraZeneca conflicts of interest dark money deception GlaxoSmithKline Johnson and Johnson Novartis Pfizer revolving doors Roche Shire Source Type: blogs

The Revolving Door Spins Again: the Now Constant Coziness Between the Health Care Industry and US Government
Just because Washington DC is now crazy town does not mean the revolving door has stopped spinning.  We have been dutifully accumulating cases, so it is time to present our latest update.I will divide this into two sections 1) the incoming revolving door, through which come people from the health care industry to enter US government positions in which they may influence health care regulation or policy relevant to their former positions; and 2) the outgoing revolving door, through which go people from US government positions in which they influenced health care regulation or policy to industry positions which were rel...
Source: Health Care Renewal - February 22, 2019 Category: Health Management Tags: DHHS Donald Trump FDA revolving doors Source Type: blogs

How to become a diabetic
It’s so easy, anyone can do it! Becoming a type 2 diabetic and proudly having to finger stick your way to blood sugar control is patriotic, as it builds revenues for Big Pharma and the healthcare industry. What better way to support your country than to help successful industries grow larger, increase shareholder value, and increase the salary and perks for hard working executives? So if you want to join the growing ranks of people who are becoming diabetic, now the largest epidemic of chronic disease ever witnessed in the history of the world, here’s what you do: Cut your fat intake — Because it leaves you ...
Source: Wheat Belly Blog - October 23, 2018 Category: Cardiology Authors: Dr. Davis Tags: News & Updates diabetes gluten gluten-free grain-free grains wheat belly Source Type: blogs

How Could Genomics Bring Precision Medicine To Healthcare?
By 2025, between 100 million and 2 billion human genomes will have been sequenced, researchers said. What do medical research, companies or governments do with such an incredible amount of data? How could genomics bring DNA-based targeted treatments, personalized drugs, and individualized clinical methods, in other words, precision medicine to healthcare? Does disease categorize people? In the previous centuries, healthcare systems focused mainly on working out generalized solutions for treating ill people in as high numbers as possible. If cough syrup was good for the majority of the coughing masses and only two people ha...
Source: The Medical Futurist - October 20, 2018 Category: Information Technology Authors: nora Tags: Biotechnology Business Genomics Healthcare Policy Medical Professionals Policy Makers Researchers future Gene genes Genetic testing genetics Genome genome sequencing Innovation personal genomics precision medicine predict Source Type: blogs

Big Pharma Wants Your DNA (But What Will They Do With It?)
It's never been a secret that the consumer DNA labs like23andMe have always intended to sell their anonymized data to other parties such as pharmaceutical companies (see: Helix Makes DNA Sequencing Available to Consumers;Where Do We Go From Here?,23andMe Customers: Suckers or Empowered Consumers?).This has always been the rationale for offering DNA testing to consumers at very low prices. After a few years, the details of such deals are beginning to emerge. A recent article spelled out some of them (see:Big Pharma Would Like Your DNA). Below is an excerpt from it:...[T]his week ’s announcement that GlaxoSmithKl...
Source: Lab Soft News - July 31, 2018 Category: Laboratory Medicine Authors: Bruce Friedman Tags: Clinical Lab Industry News Clinical Lab Testing Electronic Health Record (EHR) Genomic Testing Healthcare Innovations Lab Industry Trends Medical Consumerism Medical Research Pharmaceutical Industry Source Type: blogs

New drugs for hyperkalemia
FDA Approves Lokelma for Hyperkalemia The US Food and Drug Administration (FDA) has approved sodium zirconium cyclosilicate (Lokelma, AstraZeneca) — a medication that rapidly restores normal potassium levels — for adults with hyperkalemia. Formerly known as ZS-9, the drug is a “highly-selective, oral potassium-removing agent,” the company explains in a company news release. Hyperkalemia has become a significant problem.  With more type 2 Diabetes Mellitus, we are seeing an explosion of chronic kidney disease.  In patients with CKD 3b and 4, patients often develop hyporenin, hypoaldosterone and thus type I...
Source: DB's Medical Rants - May 21, 2018 Category: Internal Medicine Authors: rcentor Tags: Medical Rants Source Type: blogs

The debate on indication-based pricing in the U.S. and five Major European countries
This report, funded by AstraZeneca, provides an overview of the literature on IBP and how it has been implemented in the US, France, Germany, Italy, Spain and the UK. ReportSummary (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - May 14, 2018 Category: UK Health Authors: The King ' s Fund Information & Knowledge Service Tags: NHS finances and productivity Source Type: blogs

Seroquel, Atypical Antipsychotics for Insomnia, Dementia?
I’m a little dumb-founded whenever I run across a prescribing trend that goes against all of the available empirical evidence for common sense use of a medication. Nowhere is this more evident than with the prescription of atypical antipsychotic medications. It wouldn’t be too far a stretch to suggest that such prescriptions have become like Prozac prescriptions in the 1990s, the latest medication fad. But atypical antipsychotics, like Seroquel (quetiapine fumarate), are far more complex with far more problematic side effects than drugs like Prozac, and should only be prescribed for on-label use. The Washingto...
Source: World of Psychology - April 7, 2018 Category: Psychiatry & Psychology Authors: John M. Grohol, Psy.D. Tags: Antipsychotic General Medications Policy and Advocacy Adverse Effects Atypical Antipsychotic Bipolar Disorder Insomnia movement disorder Seroquel side effects Weight Gain Source Type: blogs

2018 Forecast: Another Theranos, Hospital Hiring Slows & Successful HIT Exits
By BOB KOCHER, MD and BRYAN ROBERTS For what is now an annual tradition, we are once again attempting to be healthcare soothsayers. We are proud to share with you our 10 healthcare predictions for 2018. In 2017, amaz-ingly, eight of our predictions came true. For 2018, we are betting on the following: 1. Another Theranos We think at least one healthcare information technology company with an enterprise value of more than $1 billion (not including Outcome Health, which we could not have predicted tanking so spectacularly quickly) will be exposed as not having product results to support their hype. It will also expose embar...
Source: The Health Care Blog - February 13, 2018 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Bob Kocher Bryan Roberts Venrock Capital Source Type: blogs

Join the Undoctored Revolution
Let’s take back control over personal health. Share this to expose healthcare for the corrupt enterprise it is. Imagine that you receive a letter in the mail stating “In order to retain your right to freedom of speech, you will be billed $10,000 per year every year for the rest of your life.” You would be—-understandably-—outraged. Freedom of speech in America is precious, something Americans have waged wars to defend, something we now view as a basic right, no financial price required to maintain it. It should be free and available to everyone regardless of religion, color, political leanings, or income. ...
Source: Wheat Belly Blog - February 9, 2018 Category: Cardiology Authors: Dr. Davis Tags: Undoctored Wheat Belly Lifestyle diy health Dr. Davis grain-free healthcare Source Type: blogs

The 1000th Thread!
Discussion Blog)
Source: Bioethics Discussion Blog - December 24, 2017 Category: Medical Ethics Source Type: blogs

The 1000th Thread!
This is the 1000th presentation to my bioethics blog since starting on Google Blogspot.com in 2004.There has been many topics covered. Though comments by the visitors has always been encouraged and, since as a "discussion blog", comments leading to discussions I have felt was the definitive function here. Virtually none of the thread topics have gone unread and most have had some commentary, some with mainly particularly strong and emphatic opinions http://bioethicsdiscussion.blogspot.com/2013/01/should-pathologists-be-physicians.html, some with extensive up to 12 years long continued discussion http://bioethicsdiscussion....
Source: blog.bioethics.net - December 24, 2017 Category: Medical Ethics Authors: Maurice Bernstein, M.D. Tags: Health Care syndicated Source Type: blogs